Croma PolyPhil Eye 1x2ml
Important Notice
Medical device regulated by the European Medical Device Regulation (MDR), intended exclusively for authorized healthcare professionals. By purchasing, the customer declares to be authorized for their professional activity; false information may entail legal responsibilities.
Croma PolyPhil™ Eye is the variant of the Croma-Pharma polynucleotide range formulated for the eye contour: 15 mg of PN-HPT® in a 2 ml syringe, the lowest concentration in the range. The lower polynucleotide load reflects the reduced thickness of the periocular skin, where the aim is to biostimulate without overloading the tissue.
- PN-HPT® 15 mg / 2 ml
- Hyaluronic acid not contained
- Contents 1 syringe × 2 ml
- Needles 2 × 30G ½"
- Plane intradermal
Composition and technology
- PN-HPT® polynucleotides: 15 mg per 2 ml syringe (7.5 mg/ml), obtained from freshwater trout from controlled European aquaculture, with full traceability of the production chain.
- Adapted concentration: it is the formulation with the lowest PN content in the range, together with PolyPhil Hair, designed for thin skin and delicate areas.
- PN-HPT® (Polynucleotide High Purification Technology): Croma's proprietary purification process that guarantees a high degree of purity of the polynucleotide chain.
- Mechanism of action: the polynucleotides stimulate fibroblast proliferation and the neosynthesis of collagen and elastin, retain water and act as free-radical scavengers, creating an optimal environment for fibroblast activity.
Position within the PolyPhil range
| PolyPhil | PN-HPT® 40 mg / 2 ml, without HA — face, neck, décolletage, hands, scars |
|---|---|
| PolyPhil Next | PN-HPT® 20 mg + HA 20 mg / 2 ml — mature and dehydrated skin, midface, scars and acne scars |
| PolyPhil Eye | PN-HPT® 15 mg / 2 ml — eye contour, eyelids, superficial lines |
| PolyPhil Hair | PN-HPT® 15 mg / 2 ml — scalp and eyebrows |
Note: the PhilArt line was renamed PolyPhil™ in 2024/2025. It is the same product and the same formulation.
Indications and treatment areas
- Eye contour and periorbital region
- Eyelids and brow arch
- Superficial lines of the area
- Thin, sensitive skin and delicate areas in general
A biostimulating product, not a volumiser: it acts on the quality and firmness of the skin, it does not fill the tear trough or correct palpebral fat pads.
Technique and treatment protocol
- Injection plane: intradermal.
- Technique: microdeposits (multi-puncture) with a spacing of 0.5 to 1 cm, or linear retrograde.
- Recommended needle: 30G ½" (13 mm), 2 units included.
- Dose: 1–2 ml per session.
- Protocol: 3–4 sessions with an interval of 14 to 21 days.
- Take particular care in the periorbital region: superficial injection, small volumes per point and knowledge of the vascular anatomy of the area.
Technical data
| Manufacturer | Croma-Pharma GmbH, Austria |
|---|---|
| Active substance | PN-HPT® polynucleotides 15 mg per 2 ml syringe (7.5 mg/ml) |
| Origin of the polynucleotides | Freshwater trout, controlled European aquaculture |
| Presentation | 1 pre-filled syringe of 2.0 ml |
| Needles | 2 × 30G ½" (13 mm) |
| Application plane | Intradermal |
| Classification | Medical device with CE marking 0373 |
| Use | Qualified healthcare professionals only |
Storage and pack contents
- Storage: between 2 °C and 25 °C, in a dry place protected from sunlight. Do not freeze.
- Do not use after the expiry date shown on the packaging.
- Single-use product. Do not reuse or resterilise.
- The pack contains: 1 pre-filled syringe of 2 ml, 2 needles 30G ½", information for use and traceability labels.
Contraindications and warnings
Known hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases or a history thereof; active skin infection or inflammation in the treatment area, including active herpes simplex; coagulation disorders; epilepsy; circulatory disorders; ongoing antibiotic or oncological treatment; under 18 years of age.
Always consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.
Medical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma. This data sheet does not replace the instructions for use accompanying the product.