Aliaxin GP Global Performance 2x1ml
Important Notice
Medical device regulated by the European Medical Device Regulation (MDR), intended exclusively for authorized healthcare professionals. By purchasing, the customer declares to be authorized for their professional activity; false information may entail legal responsibilities.
ALIAXIN® GP Global Performance from IBSA Derma is the versatile reference of the Aliaxin range: 25 mg/ml of cross-linked hyaluronic acid and 2.5 mg/ml of free hyaluronic acid, with chains of 1,000 and 2,000 kDa. With an elasticity value of 95 Pa and intermediate flow behaviour, it covers the range from the correction of folds and deep wrinkles to moderate volumising, in the deep dermis and the subcutaneous plane.
- Cross-linked HA 25 mg/ml
- Free HA 2.5 mg/ml
- Contents 2 syringes × 1 ml
- Needles 2 × 27G 13 mm + 2 × 27G 19 mm
- Plane deep dermis / subcutaneous
Composition and technology
- Cross-linked hyaluronic acid: 25 mg/ml, of non-animal origin, obtained by bacterial fermentation.
- Free (non-cross-linked) hyaluronic acid: 2.5 mg/ml, providing lubrication during injection and immediate hydration of the tissue.
- Molecular weights: combination of 1,000 kDa and 2,000 kDa chains.
- Cross-linking with BDDE at a low percentage: degree of cross-linking below 10 %, with a BDDE residue below 0.1 ppm. The result is a gel with smooth extrusion and good tissue integration.
- SHYALT technology: IBSA's proprietary method for obtaining ultrapure hyaluronic acid, common to the entire Aliaxin range.
- Rheological profile: elasticity (lift) 95 Pa; flow 0.23; sculpt 0.16. This is the balance that justifies the name "Global Performance": enough elasticity to support a deep fold, enough fluidity to work in the dermis.
- The formulation does not include a local anaesthetic.
Differences between the references in the Aliaxin range
| Aliaxin FL — Fine Lines | 25 mg/ml; 500 + 1,000 kDa; lift 45 Pa — mid/deep dermis: fine lines, lip contour, perioral wrinkles |
|---|---|
| Aliaxin GP — Global Performance | 25 mg/ml; 1,000 + 2,000 kDa; lift 95 Pa — deep dermis/subcutaneous: nasolabial fold, glabella, marionette lines, malar and chin volume |
| Aliaxin EV — Essential Volume | 25 mg/ml; 1,000 + 2,000 kDa; lift 162 Pa — deep subcutaneous: zygomatic region, jawline, temples |
| Aliaxin SV — Superior Volume | 25 mg/ml; 2,300 kDa; lift 295 Pa — deep/supraperiosteal plane: cheekbones, mandibular angle, chin |
| Aliaxin LV — Lips Volume | 25 mg/ml; 1,000 + 2,000 kDa — labial submucosa: lip volumising |
The five references share the same hyaluronic acid concentration (25 mg/ml cross-linked + 2.5 mg/ml free). What differentiates them is the combination of molecular weights and the resulting rheological behaviour, which determines the injection plane and the indication.
Indications and treatment areas
Injectable implant indicated for the redefinition of the facial contour and the correction of the most frequent facial imperfections, of medium to deep depth.
- Nasolabial fold
- Marionette lines and oral commissures
- Glabellar and forehead wrinkles
- Perioral wrinkles
- Tear trough
- Moderate malar and chin volumising
- Acne scars and depressed facial scars
Technique and treatment protocol
- Injection plane: deep dermis and subcutaneous plane, according to the area and the correction sought.
- Needles included: 2 × 27G × 13 mm and 2 × 27G × 19 mm.
- Technique: linear, fanning or cross-hatching retrograde injection for folds; microdeposits for superficial wrinkles; bolus in the deep plane for volumising.
- Aspiration and retrograde injection in accordance with the usual clinical protocol. In the tear trough, a deep, preperiosteal plane and conservative volumes are recommended.
- Never inject intravascularly. Do not apply in areas with permanent implants.
- Do not combine in the same session with laser, deep peeling or dermabrasion.
- The amount and the number of sessions are determined according to the degree of correction sought and the individual response.
Technical data
| Manufacturer | IBSA Derma — IBSA Institut Biochimique SA, Switzerland |
|---|---|
| Active substance | Cross-linked hyaluronic acid 25 mg/ml + free hyaluronic acid 2.5 mg/ml |
| Molecular weights | 1,000 kDa and 2,000 kDa |
| Cross-linker | BDDE — degree of cross-linking < 10 %, residue < 0.1 ppm |
| Technology | SHYALT (ultrapure hyaluronic acid); Hydrolift® Action |
| Rheological profile | Lift 95 Pa; flow 0.23; sculpt 0.16 |
| Anaesthetic | Not contained |
| Presentation | 2 pre-filled syringes of 1.0 ml |
| Needles | 2 × 27G × 13 mm + 2 × 27G × 19 mm |
| Application plane | Deep dermis / subcutaneous |
| Classification | Medical device with CE marking |
| Use | Qualified healthcare professionals only |
Storage and pack contents
- Storage: between 2 °C and 25 °C, in a dry place protected from direct sunlight. Do not freeze.
- Do not use after the expiry date shown on the packaging.
- Single-use product. Do not reuse or resterilise.
- The pack contains: 2 pre-filled syringes of 1.0 ml in a sterile blister, 4 sterile needles (2 × 27G × 13 mm and 2 × 27G × 19 mm), package leaflet and adhesive traceability labels for the patient record.
Contraindications and warnings
Contraindications: known hypersensitivity to hyaluronic acid or to any of the components; active skin infection or inflammation in the treatment area, including active herpes simplex or acne in the inflammatory phase; tendency to hypertrophic or keloid scarring; autoimmune diseases; coagulation disorders or anticoagulant or antiplatelet therapy; pregnancy and breastfeeding; under 18 years of age.
Warnings: do not inject intravascularly, intramuscularly or into tendons. Do not mix with other products in the same syringe. Do not apply over areas previously treated with permanent implants. Individual assessment in immunocompromised patients or in those with a history of multiple allergies.
Always consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.
Medical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of IBSA Derma. This data sheet does not replace the instructions for use accompanying the product.