{"title":"FACE PRODUCTS","description":"\u003cp\u003ePiel Eterna’s complete facial catalogue in one category: fillers such as Revolax Deep, biostimulators such as Sculptra, skinboosters such as Profhilo H+L, and mesotherapy products such as Fillmed NCTF 135HA, enabling clinics to create any facial harmonisation or skin-quality protocol without looking elsewhere.\u003c\/p\u003e\u003cp\u003eAll references are original products from official manufacturers and distributors, with CE marking, batch numbers, and expiry dates verifiable on every delivery note in accordance with MDR Regulation (EU) 2017\/745. For sale exclusively to healthcare professionals.\u003c\/p\u003e","products":[{"product_id":"profhilo","title":"Profhilo H+L 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eProfhilo® H+L from IBSA Derma is not a dermal filler: it is a bio-remodelling product based on \u003cb\u003enon-cross-linked\u003c\/b\u003e hyaluronic acid. Each 2 ml syringe delivers 64 mg of ultrapure hyaluronic acid — 32 mg of high molecular weight and 32 mg of low molecular weight — stabilised by NAHYCO® thermal technology, without any chemical cross-linking agent. It is applied with the fixed BAP protocol: 5 defined points per hemiface, 10 in total, in two sessions one month apart.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 64 mg \/ 2 ml (3.2 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eH-HA + L-HA\u003c\/b\u003e 32 mg + 32 mg\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 29G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e BAP, 10 points, 2 sessions\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eHigh molecular weight hyaluronic acid (H-HA):\u003c\/b\u003e 32 mg per 2 ml syringe, with a molecular weight of 1,100–1,400 kDa.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLow molecular weight hyaluronic acid (L-HA):\u003c\/b\u003e 32 mg per 2 ml syringe, with a molecular weight of 80–100 kDa.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTotal concentration:\u003c\/b\u003e 64 mg \/ 2 ml, equivalent to 32 mg\/ml (3.2 %). Sodium salt of hyaluronic acid of microbial origin, obtained by biofermentation and without chemical modification.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eExcipients:\u003c\/b\u003e physiological solution buffered with sodium chloride, sodium phosphate and water for injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNAHYCO® technology:\u003c\/b\u003e patented thermal process of controlled heating and cooling that breaks the hydrogen bonds of the mixture and allows the formation of new bonds between the high and low molecular weight chains. The result is stable Hybrid Cooperative Complexes (\u003ci\u003eHybrid Cooperative Complexes\u003c\/i\u003e, HCC). \u003cb\u003eNeither BDDE nor any other chemical cross-linker is used\u003c\/b\u003e, unlike conventional hyaluronic acid fillers.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eFunctional difference:\u003c\/b\u003e as it is not cross-linked, the product provides neither projection nor volume support. Its behaviour is that of a low-viscosity, highly diffusing gel, which distributes within the tissue plane instead of remaining localised like an implant.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Profhilo variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo H+L\u003c\/th\u003e\u003ctd\u003e64 mg \/ 2 ml (32 mg H-HA + 32 mg L-HA) — laxity and remodelling of the facial contour, dermal\/subcutaneous plane, BAP technique with a 29G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Structura\u003c\/th\u003e\u003ctd\u003e90 mg \/ 2 ml (45 mg H-HA + 45 mg L-HA) — volume loss due to atrophy of facial adipose tissue, superficial fat compartment, application with a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Body\u003c\/th\u003e\u003ctd\u003e96 mg \/ 3 ml per syringe, 2 syringes — body skin laxity (abdomen, inner surface of the arms, knees), body BAP technique at 10 points\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll three variants share NAHYCO® technology and the absence of a chemical cross-linker. They differ in concentration, application plane and pattern of points.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable medical device indicated, according to the manufacturer's instructions for use, for the \u003cb\u003etreatment of the malar-zygomatic and submalar areas of the face, for the redefinition of the contour and the remodelling of skin laxity\u003c\/b\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMalar and zygomatic region\u003c\/li\u003e\n\u003cli\u003eSubmalar region\u003c\/li\u003e\n\u003cli\u003eMandibular angle and chin, within the BAP point scheme\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eProfhilo H+L is not indicated for the correction of individual wrinkles or for volumetric restoration; cross-linked fillers are used for that purpose or, in the case of adipose atrophy, Profhilo Structura.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol — BAP points\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe \u003cb\u003eBAP\u003c\/b\u003e protocol (\u003ci\u003eBio Aesthetic Points\u003c\/i\u003e) defines five anatomically fixed injection points per hemiface, selected for their low vascular risk and their diffusion capacity. \u003cb\u003e0.2 ml per point\u003c\/b\u003e is injected as a bolus, in the dermal\/subcutaneous plane, with gentle massage afterwards.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003e1 — Zygomatic prominence:\u003c\/b\u003e highest point of the zygomatic arch, approximately 2 cm from the lateral canthus of the eye.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e2 — Nasal base:\u003c\/b\u003e intersection between the horizontal line running from the nasal ala towards the tragus and the perpendicular descending from the pupil.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e3 — Tragus:\u003c\/b\u003e approximately 1 cm in front of the lower margin of the tragus.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e4 — Mandibular angle:\u003c\/b\u003e around 1 cm above the angle of the mandible.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e5 — Chin:\u003c\/b\u003e approximately 1.5 cm towards the oral commissure from the mental reference point.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e 1 ml per hemiface, maximum 2 ml (10 points) per session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 29G ½\" (0.33 × 12 mm), 2 units included.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInitial cycle:\u003c\/b\u003e two sessions with an interval of 30 days, with the same dose and the same points in both.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMaintenance:\u003c\/b\u003e the manufacturer provides for maintenance sessions from 2 months onwards, with a maximum of seven treatments over a 12-month period.\u003c\/li\u003e\n\u003cli\u003eAfter injection, it is recommended to avoid exposure to ultraviolet radiation for 3–5 days and to use SPF 50 sun protection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eIBSA Derma — IBSA Farmaceutici Italia \/ IBSA Institut Biochimique SA, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eSodium salt of non-cross-linked hyaluronic acid, 64 mg \/ 2 ml (32 mg\/ml)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eFractions\u003c\/th\u003e\u003ctd\u003e32 mg H-HA (1,100–1,400 kDa) + 32 mg L-HA (80–100 kDa)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin\u003c\/th\u003e\u003ctd\u003eMicrobial biofermentation, without chemical modification\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eNone — NAHYCO® thermal stabilisation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 29G ½\" (0.33 × 12 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eDermal \/ subcutaneous (intradermal use)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device for intradermal use\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 0 °C and 25 °C, away from heat sources. \u003cb\u003eDo not freeze.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise. Sterile and pyrogen-free contents.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2.0 ml, 2 needles 29G ½\", instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eManufacturer's warnings:\u003c\/b\u003e for intradermal use only. Do not inject intravenously, intramuscularly or into tendons. Do not mix with other products in the same syringe. It must not be used concomitantly with laser \u003ci\u003eresurfacing\u003c\/i\u003e treatments or with medium-to-deep peels.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to any of the components; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; patients under 18 years of age. Individual assessment in patients with autoimmune disease, coagulation disorders or anticoagulant therapy.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the instructions for use and the official documentation of IBSA Derma. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"IBSA","offers":[{"title":"Default Title","offer_id":51007627788628,"sku":"PRO002","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/profhio_hl.jpg?v=1746786717"},{"product_id":"ejal40","title":"EJAL40 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eEJAL40 is a biorevitalisation gel based on non-cross-linked hyaluronic acid, presented in a single-dose 2 ml vial, intended to improve skin quality, hydration and elasticity. This data sheet has been drafted restrictively: it has not been possible to verify the manufacturer's technical documentation for this reference, so concentrations and numerical protocols are deliberately omitted.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eActive substance\u003c\/b\u003e non-cross-linked HA\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 vial × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eUse\u003c\/b\u003e biorevitalisation\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRoute\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eEJAL40 is a solution of non-cross-linked hyaluronic acid for skin biorevitalisation. As it is not cross-linked, the product does not provide structural volume: it acts by improving dermal hydration and skin quality.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNote on the figures:\u003c\/b\u003e the hyaluronic acid concentration and the molecular weight could not be verified in the manufacturer's official documentation and, as an editorial policy, are not reproduced here. For the binding detail, consult the package leaflet accompanying the product or request the manufacturer's technical data sheet from us.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eUsual indications for this product category:\u003c\/b\u003e skin dehydration, loss of elasticity and firmness, dull skin, fine lines and early signs of photoageing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace\u003c\/li\u003e\n\u003cli\u003eNeck and décolletage\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable product for intradermal administration by microinjections (mesotherapy, microdeposits or linear retrograde threading, according to medical assessment), on healthy and rigorously disinfected skin, under aseptic conditions.\u003c\/p\u003e\n\u003cp\u003eWe have no manufacturer's documentation establishing the needle gauge, the dose per session, the number of sessions or the interval between them. The binding protocol is the one set out in the instructions for use included in the pack.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eBrand\u003c\/th\u003e\u003ctd\u003eEJAL40\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid (concentration not verified)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 vial of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eNot verified in the manufacturer's documentation; consult the packaging labelling\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e1 sterile vial of 2 ml.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003eStore as indicated on the packaging, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eGeneral precautions applicable to intradermal injectables: known hypersensitivity to any of the components; active skin infection, inflammation or lesion in the treatment area; coagulation disorders; autoimmune diseases; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eThe binding contraindications are exclusively those set out in the official documentation accompanying the product. Always consult it before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eProduct intended exclusively for qualified healthcare professionals. For this reference no public technical documentation from the manufacturer has been found; the data sheet has been drafted restrictively and deliberately omits values that cannot be verified. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Medixa","offers":[{"title":"Default Title","offer_id":51007628018004,"sku":"EJA001","price":36.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/ejal40_d059a522-a1cf-47e3-a2a1-5d9bfd4af251.jpg?v=1747749687"},{"product_id":"profhilo-body-kit","title":"Profhilo Body Kit","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eProfhilo® Body Kit from IBSA Derma is the complete body protocol of the Profhilo range: two pre-filled 3 ml syringes with 96 mg of \u003cb\u003enon-cross-linked\u003c\/b\u003e hyaluronic acid per syringe, plus the Profhilo Figura patch and cream as complementary treatment. It is applied with the body BAP technique, at 10 defined injection points, on areas of skin laxity of the body.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 96 mg \/ 3 ml per syringe\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 3 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eKit\u003c\/b\u003e injectable + patch + cream\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique\u003c\/b\u003e body BAP, 10 points\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 2 sessions \/ 1 month\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 96 mg per 3 ml syringe, equivalent to 32 mg\/ml (3.2 %), in the form of a stabilised hybrid complex of high and low molecular weight.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNAHYCO® technology:\u003c\/b\u003e patented thermal stabilisation process that combines the high and low molecular weight fractions without resorting to chemical agents. The manufacturer describes the result as a stabilised hyaluronic acid molecule \u003cb\u003e100 % free of chemical stabilisers\u003c\/b\u003e. No BDDE is used.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G' of 39 Pa and tan δ of 1.36. Values characteristic of a fluid, highly diffusing gel, not of a volumetric implant.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eComplementary components of the kit:\u003c\/b\u003e Profhilo Figura body patch, applied immediately after the session, and Profhilo Figura body cream for home use between sessions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Profhilo variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo H+L\u003c\/th\u003e\u003ctd\u003e64 mg \/ 2 ml (32 mg H-HA + 32 mg L-HA) — laxity and remodelling of the facial contour, dermal\/subcutaneous plane, facial BAP technique at 10 points\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Structura\u003c\/th\u003e\u003ctd\u003e90 mg \/ 2 ml (45 mg H-HA + 45 mg L-HA) — atrophy of facial adipose tissue, superficial fat compartment, application with a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Body Kit\u003c\/th\u003e\u003ctd\u003e96 mg \/ 3 ml per syringe, 2 syringes + patch + cream — body skin laxity, body BAP technique at 10 points\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll three variants share NAHYCO® technology and the absence of a chemical cross-linker. The body reference differs in syringe volume (3 ml versus 2 ml), in the pattern of points and in the topical products included in the kit.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eIndicated for the treatment of body skin laxity in areas with loss of elasticity and firmness.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAbdomen\u003c\/li\u003e\n\u003cli\u003eInner surface of the arms\u003c\/li\u003e\n\u003cli\u003eKnees\u003c\/li\u003e\n\u003cli\u003eDécolletage\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is not a product for the treatment of localised adiposity nor a substitute for body remodelling procedures: it acts on the quality and firmness of the skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e dermal \/ subcutaneous.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBody BAP technique:\u003c\/b\u003e 10 injection points defined per treatment area, with \u003cb\u003e0.3 ml of product per point\u003c\/b\u003e, following the same principle of fixed anatomical points as the facial protocol. IBSA provides a dedicated BAP marking tool for locating the points.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e one 3 ml syringe per treatment area and session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eKit protocol, in three steps:\u003c\/b\u003e\n\u003col\u003e\n\u003cli\u003eInjection session with the body BAP technique.\u003c\/li\u003e\n\u003cli\u003eApplication of the Profhilo Figura patch for 2–3 hours after the session.\u003c\/li\u003e\n\u003cli\u003eHome use of the Profhilo Figura body cream between sessions.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCycle:\u003c\/b\u003e two injection sessions with an interval of one month.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eIBSA Derma — IBSA Institut Biochimique SA, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid, 96 mg \/ 3 ml (32 mg\/ml)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eStructure\u003c\/th\u003e\u003ctd\u003eStabilised hybrid complex of high and low molecular weight\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eNone — NAHYCO® thermal stabilisation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheological profile\u003c\/th\u003e\u003ctd\u003eG' 39 Pa; tan δ 1.36\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 3.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eKit accessories\u003c\/th\u003e\u003ctd\u003eProfhilo Figura body patch and body cream\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eDermal \/ subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 0 °C and 25 °C, away from heat sources. \u003cb\u003eDo not freeze.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eThe syringes are single-use. Do not reuse or re-sterilise. Sterile and pyrogen-free contents.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe kit contains:\u003c\/b\u003e 2 pre-filled syringes of 3.0 ml of Profhilo Body, Profhilo Figura body patch, Profhilo Figura body cream, instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eManufacturer's warnings:\u003c\/b\u003e do not inject intravenously, intramuscularly or into tendons. Do not mix with other products in the same syringe. It must not be used concomitantly with laser \u003ci\u003eresurfacing\u003c\/i\u003e treatments or with medium-to-deep peels. After injection it is recommended to avoid exposure to ultraviolet radiation for 3–5 days and to use SPF 50 sun protection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to any of the components; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; patients under 18 years of age. Individual assessment in patients with autoimmune disease, coagulation disorders or anticoagulant therapy.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of IBSA Derma. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"IBSA","offers":[{"title":"Default Title","offer_id":51007628247380,"sku":"PRO001","price":235.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/profhilo_bodykit_1.jpg?v=1747772712"},{"product_id":"11939","title":"Belotero Revive 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eBELOTERO® Revive is not a volumetric filler but the injectable revitaliser of the Merz Aesthetics range: cross-linked sodium hyaluronate at 20 mg\/ml combined with glycerol at 17.5 mg\/ml. The glycerol acts as a humectant for the cutaneous tissue and is what distinguishes Revive from the rest of the range. Its Instructions for Use indication is the revitalisation of early-onset photodamaged facial skin on the cheeks.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycerol\u003c\/b\u003e 17.5 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e up to 9 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked sodium hyaluronate:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, high molecular weight (2.7–3.3 m³\/kg).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycerol:\u003c\/b\u003e 17.5 mg\/ml. Acts as a humectant for the cutaneous tissue to preserve hydration.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e BDDE, degree of modification \u0026lt; 5 %. Residual BDDE ≤ 2 ppm.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhysiological phosphate buffer pH 7\u003c\/b\u003e q.s. to 1.0 ml, with sodium dihydrogen phosphate dihydrate 1.5 mg\/ml and disodium phosphate 5.5 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout lidocaine.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCPM® technology:\u003c\/b\u003e gel with variable cross-linking densities. Revive is characterised by a lower gel density that allows the product to diffuse into the fine spaces of the pericellular tissue; its viscoelastic properties establish a condensed network within the extracellular matrix to improve skin turgor and hydration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the BELOTERO® range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSoft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml · modification \u0026lt; 5 % · superficial to mid dermis · fine perioral lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBalance Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 22.5 mg\/ml · modification \u0026lt; 8 % · superficial to mid dermis and infraorbital supraperiosteal plane · moderate wrinkles and folds, lips, infraorbital hollow\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25.5 mg\/ml · modification \u0026lt; 8 % · deep dermis · deep folds, marionette lines, lip enhancement\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eLips Shape\u003c\/th\u003e\u003ctd\u003eHA 25.5 mg\/ml · deep dermis and labial mucosa · volume and vermilion border\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVolume Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 26 mg\/ml · modification \u0026lt; 10 % · deep subcutaneous or supraperiosteal · cheeks, temples, chin, severe NLFs\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRevive\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml + glycerol 17.5 mg\/ml · without lidocaine · mid and deep dermis · skin revitalisation, not volumetric filling\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eRevive is the only reference in the range that incorporates glycerol and the only one whose purpose is not to fill a fold or provide volume, but to improve skin hydration, elasticity and firmness.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eResorbable injectable implant intended to revitalise the skin of the face by rehydrating dry and very dry skin, improving elasticity and firmness and smoothing fine superficial wrinkles, reducing skin roughness.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInstructions for Use indication:\u003c\/b\u003e revitalisation of early-onset photodamaged facial skin \u003cb\u003eon the cheeks\u003c\/b\u003e, characterised by dehydration, loss of elasticity and firmness and the presence of fine superficial wrinkles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eMust not be injected\u003c\/b\u003e into the glabellar or nasal region, into blood vessels, into skin with active inflammation or infection, or into areas previously treated with a permanent filler.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e up to 9 months according to the manufacturer's clinical data.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid and deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 × 30G ½\".\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique recommended by the manufacturer:\u003c\/b\u003e serial micropuncture — several injections of very small amounts distributed evenly, approximately \u003cb\u003e50 µl per point, with 20–30 points spaced 1–2 cm\u003c\/b\u003e apart.\u003c\/li\u003e\n\u003cli\u003eOther accepted techniques: linear or serial threading, fanning and cross-hatching.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDosing guidance:\u003c\/b\u003e up to 3 ml in the cheeks in a single session, or three sessions with a maximum of 2 ml per session separated by at least 4 weeks. The regimen may be repeated at the earliest after 6 months, with a maximum annual dose of 12 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e prior aspiration, low volumes and serial injections in high-risk areas, treating one side at a time and manual occlusion of the origin of the supratrochlear vessels. Blunt cannulas reduce the risk but do not eliminate it.\u003c\/li\u003e\n\u003cli\u003eDo not overcorrect. Gently massage the treated area if necessary.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAftercare:\u003c\/b\u003e observation of up to 30 minutes after injection; avoid alcohol 24 h before and after; no make-up for at least 12 h; avoid sauna, peels, steam baths, prolonged sun exposure, UV and extreme temperatures for 2 weeks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAnteis SA, Chemin des Aulx 18, 1228 Plan-les-Ouates, Switzerland (Merz Aesthetics)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEU representative\u003c\/th\u003e\u003ctd\u003eMerz Aesthetics GmbH, Frankfurt am Main, Germany\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked sodium hyaluronate 20 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSecond component\u003c\/th\u003e\u003ctd\u003eGlycerol 17.5 mg\/ml (humectant)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE, degree of modification \u0026lt; 5 %; residual ≤ 2 ppm\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eCPM® (Cohesive Polydensified Matrix)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7 (physiological phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled glass syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\"\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ sterile CE-marked needles\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking in accordance with Regulation (EU) 2017\/745; product without an intended medical purpose (Implementing Regulation (EU) 2022\/2346)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C. Protect from light. Do not freeze. Store in a dry place and avoid mechanical impact.\u003c\/li\u003e\n\u003cli\u003eVisually inspect the integrity of the packaging and of the sterile barrier system before use. Do not use after the expiry date.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not resterilise or reuse.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled glass syringe of 1.0 ml, 2 sterile 30G ½\" needles, traceability labels, implant card, instructions for use and patient information leaflet.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to any of the components, in particular to sodium hyaluronate, to glycerol or to BDDE; pregnancy and breastfeeding; under 18 years of age; general infection; active autoimmune disease.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDo not inject\u003c\/b\u003e into blood vessels, into the glabellar or nasal region, into skin with active inflammation or infection, or into areas treated with a permanent dermal filler.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e rare but serious events associated with intravascular injection of facial fillers have been reported — vascular occlusion, visual impairment, blindness, cerebral ischaemia or haemorrhage, skin necrosis. Stop the injection immediately in the event of changes in vision, signs of stroke, skin blanching or unusual pain, and refer for urgent medical care. Sodium hyaluronate precipitates in the presence of quaternary ammonium salts (e.g. benzalkonium chloride).\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions:\u003c\/b\u003e individual assessment in cases of a history of multiple severe allergies or anaphylactic shock; not recommended in cases of a history of streptococcal disease or a tendency to hypertrophic or keloid scarring; anticoagulants, antiplatelet agents and NSAIDs increase the risk of haematoma; do not combine with peeling, dermabrasion or laser before complete healing and, in any case, not before 2 weeks. The implant card must be presented to the radiologist before magnetic resonance imaging.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of BELOTERO® Revive (Anteis SA \/ Merz Aesthetics, Spanish version V04, 23-02-2026). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Merz Aesthetics","offers":[{"title":"Default Title","offer_id":51007629164884,"sku":"BEL004","price":80.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/belotero_revive_fd34ebd1-1997-4103-9b2d-d17d35c5d5ab.jpg?v=1747766759"},{"product_id":"11943","title":"Belotero Volume Lidocaine 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eBELOTERO® Volume Lidocaine is the volumetric gel of the Merz Aesthetics range: cross-linked sodium hyaluronate at 26 mg\/ml, the highest concentration in the line, with the highest degree of BDDE modification (\u0026lt; 10 %) and CPM® technology. It is injected into the deep subcutaneous or supraperiosteal plane to restore facial volumes. Presented as 2 syringes of 1 ml.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 26 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 27G ½\" and 30G ½\" per syringe\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e up to 18 months (NLF)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked sodium hyaluronate:\u003c\/b\u003e 26 mg\/ml, of non-animal origin, high molecular weight (3.0–3.3 m³\/kg).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml (0.3 %).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e BDDE, degree of modification \u0026lt; 10 % — the highest in the range, the basis of its projection capacity. Residual BDDE ≤ 10 ppm.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhysiological phosphate buffer pH 7\u003c\/b\u003e q.s. to 1 ml, with sodium chloride 8 mg\/ml, sodium dihydrogen phosphate dihydrate 0.5 mg\/ml and disodium phosphate dodecahydrate 2.4 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCPM® technology:\u003c\/b\u003e polydensified monophasic matrix. The denser gel fractions mechanically lift the area and provide structural support to the soft tissue; the lower-density fractions diffuse into the pericellular spaces, which maintains tissue integration even in a projecting gel.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the BELOTERO® range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSoft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml · modification \u0026lt; 5 % · superficial to mid dermis · fine perioral lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBalance Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 22.5 mg\/ml · modification \u0026lt; 8 % · superficial to mid dermis and infraorbital supraperiosteal plane · moderate wrinkles and folds, lips, infraorbital hollow\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25.5 mg\/ml · modification \u0026lt; 8 % · deep dermis · deep folds, marionette lines, lip enhancement\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eLips Shape\u003c\/th\u003e\u003ctd\u003eHA 25.5 mg\/ml · deep dermis and labial mucosa · volume and vermilion border\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVolume Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 26 mg\/ml · modification \u0026lt; 10 % · deep subcutaneous or supraperiosteal · cheeks, temples, chin, severe NLFs\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRevive\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml + glycerol 17.5 mg\/ml · mid and deep dermis · skin revitalisation, not volumetric filling\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eVolume is the only gel in the range intended for the deep subcutaneous and supraperiosteal plane, and the only one with an Instructions for Use indication for the temples and chin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBiodegradable injectable implant intended for the restoration of facial volumes in adults.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCheek enhancement\u003c\/li\u003e\n\u003cli\u003eTemples\u003c\/li\u003e\n\u003cli\u003eChin\u003c\/li\u003e\n\u003cli\u003eSevere nasolabial folds\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eMust not be injected\u003c\/b\u003e into the glabellar or nasal region, into blood vessels, into skin with active inflammation or infection, or into areas previously treated with a permanent filler.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e up to 18 months in nasolabial folds and up to 12 months in cheeks, temples and chin, according to the manufacturer's clinical data.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep subcutaneous layers or above the periosteum.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e each syringe is supplied with 2 sterile needles (27G ½\" and 30G ½\"); 4 needles per pack. The 30G ½\" needle requires greater injection force.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended techniques:\u003c\/b\u003e linear or serial threading, fanning, cross-hatching and serial (micro)puncture.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMaximum volumes per indication:\u003c\/b\u003e 8 ml in the cheeks, 6 ml in the temples, 5 ml in the chin and 4 ml in the nasolabial folds. Maximum 8 ml per session (equivalent to 24 mg of lidocaine). Treatments in the same anatomical region must be separated by at least 2 weeks.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e injection in the area of the nasolabial folds or in the temples may cause vascular occlusion. Reduce the risk by prior aspiration, low volumes, serial injections, treating one side at a time and manual occlusion of the origin of the supratrochlear vessels.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCombination:\u003c\/b\u003e must not be combined with peeling, dermabrasion or laser before complete healing and, in any case, not before 2 weeks. It may be used with other BELOTERO products in the same session, but in different facial areas.\u003c\/li\u003e\n\u003cli\u003eDo not overcorrect. Gently massage the treated area if necessary.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAnteis SA, Chemin des Aulx 18, 1228 Plan-les-Ouates, Switzerland (Merz Aesthetics)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEU representative\u003c\/th\u003e\u003ctd\u003eMerz Aesthetics GmbH, Frankfurt am Main, Germany\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked sodium hyaluronate 26 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE, degree of modification \u0026lt; 10 %; residual ≤ 10 ppm\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eCPM® (Cohesive Polydensified Matrix)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7 (physiological phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled glass syringes of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 in total: 2 × 27G ½\" and 2 × 30G ½\"\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ sterile CE-marked needles\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking in accordance with Regulation (EU) 2017\/745; product without an intended medical purpose (Implementing Regulation (EU) 2022\/2346)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C. Protect from light. Do not freeze. Store in a dry place and avoid mechanical impact.\u003c\/li\u003e\n\u003cli\u003eVisually inspect the integrity of the packaging and of the sterile barrier system before use. Do not use after the expiry date.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not resterilise or reuse.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled glass syringes of 1.0 ml, 4 sterile needles (2 × 27G ½\" and 2 × 30G ½\"), traceability labels, implant card, instructions for use and patient information leaflet.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to any of the components, in particular to sodium hyaluronate, to BDDE, to lidocaine hydrochloride or to other amide-type local anaesthetics; pregnancy and breastfeeding; under 18 years of age; general infection; active autoimmune disease.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDo not inject\u003c\/b\u003e into blood vessels, into the glabellar or nasal region, into skin with active inflammation or infection, or into areas treated with a permanent dermal filler.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e rare but serious events associated with intravascular injection of facial fillers have been reported — vascular occlusion, visual impairment, blindness, cerebral ischaemia or haemorrhage, skin necrosis. Stop the injection immediately in the event of changes in vision, signs of stroke, skin blanching or unusual pain, and refer for urgent medical care. Sodium hyaluronate precipitates in the presence of quaternary ammonium salts (e.g. benzalkonium chloride).\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions:\u003c\/b\u003e individual assessment in cases of a history of multiple severe allergies or anaphylactic shock, epilepsy, cardiac disease, severe hepatic or renal impairment and porphyria; not recommended in cases of a history of streptococcal disease or a tendency to hypertrophic or keloid scarring; anticoagulants, antiplatelet agents and NSAIDs increase the risk of haematoma; lidocaine may give a positive result in anti-doping tests. The risk of granuloma, ischaemia, necrosis and vascular occlusion is greater with deep injections and high volumes.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of BELOTERO® Volume Lidocaine (Anteis SA \/ Merz Aesthetics, Spanish version V04, 23-02-2026). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Merz Aesthetics","offers":[{"title":"Default Title","offer_id":51007629623636,"sku":"BEL006","price":180.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/belotero_volume.jpg?v=1747766684"},{"product_id":"juveder-volift","title":"Juvederm Volift 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJuvéderm® VOLIFT® with lidocaine is the VYCROSS® gel from Allergan Aesthetics for the deep dermis: cross-linked hyaluronic acid at 17.5 mg\/ml with lidocaine and a 30G needle. Its instructions for use indicate it for deep cutaneous depressions, for facial contouring and for volume restoration in the lips, cheeks, chin and lower third. It is the reference in the range with the longest documented duration in the nasolabial fold.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 17.5 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 59.4 % responders at 18 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid gel:\u003c\/b\u003e 17.5 mg per ml, of non-animal origin.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg per ml (0.3 %), included to reduce patient pain during treatment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.2 q.s. to 1 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking agent:\u003c\/b\u003e butanediol diglycidyl ether (BDDE) in trace amounts (\u0026lt; 2 ppm).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVYCROSS® technology:\u003c\/b\u003e a combination of high- and low-molecular-weight hyaluronic acid with high cross-linking efficiency. It produces a gel of homogeneous texture and lower water uptake at a moderate total HA concentration — in VOLIFT® this balance translates into a gel with supporting capacity in the deep dermis yet flexible in highly mobile areas such as the lower facial third.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eVOLIFT® is the transition point of the VYCROSS® range between dermal filling and volumising: it works in the deep dermis and labial mucosa, not in the supraperiosteal plane, which corresponds to VOLUMA® and VOLUX™.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 2\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid dermis · medium-sized depressions and lip definition\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 3\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · mid and\/or deep dermis · medium and deep depressions, lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 4\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · deep dermis · deep depressions, lip augmentation and cheekbone augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA SMILE\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid and\/or deep dermis · lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSKINVIVE™ by Juvéderm® (formerly VOLITE™)\u003c\/th\u003e\u003ctd\u003eHA 12 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · intradermal · skin quality: hydration, elasticity, fine lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLBELLA®\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · superficial\/mid dermis and labial mucosa · fine lines, lips and infraorbital region\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003e\u003cb\u003eJuvéderm® VOLIFT® — this product\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA 17.5 mg\/ml · VYCROSS® · 2 × 1 ml · 30G½\" · deep dermis or labial mucosa · deep depressions, facial contouring, lips\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUMA®\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous, supraperiosteal or deep dermis · facial volume restoration\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUX™\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous and supraperiosteal · restoring and creating volume (chin and jawline)\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003eWhen to choose VOLIFT® over its neighbours:\u003c\/b\u003e compared with VOLBELLA® (15 mg\/ml), when the depression is deep rather than a fine line, and when structural support is required for facial contouring. Compared with VOLUMA® (20 mg\/ml), when injecting into the deep dermis rather than the subcutaneous or supraperiosteal plane, and when the lip forms part of the treatment plan — the instructions for use of VOLUMA® contraindicate the lip, whereas those of VOLIFT® explicitly include it. Compared with ULTRA 3 and ULTRA 4 (24 mg\/ml, HYLACROSS™), when documented duration and lower post-treatment water uptake are the priority.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable implant indicated for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDeep cutaneous depressions associated with premature ageing (nasolabial fold, marionette lines)\u003c\/li\u003e\n\u003cli\u003eFacial contouring and volume restoration to correct structural defects of the face such as asymmetries, contour deformities or volume loss\u003c\/li\u003e\n\u003cli\u003eLips, cheeks, chin and lower facial third\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis or labial mucosa.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindicated areas:\u003c\/b\u003e periorbital region (eyelids, tear trough area, crow's feet) and glabellar region. It is not indicated for breast augmentation or reconstruction.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eRoute of administration:\u003c\/b\u003e intradermal injections and injections into the labial mucosa only.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 4 units of 30G ½\", sterilised by irradiation, for exclusive use with this product.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCannulas accepted by the manufacturer:\u003c\/b\u003e sterile Easyflow System-20 cannulas of 30G × 19 mm (ref. 94323), 30G × 25 mm (ref. 94324), 27G × 25 mm (ref. 94325), 27G × 38 mm (ref. 94326) and 25G × 38 mm (ref. 94327). The 25G cannula is not recommended for the lip indication. The choice of length is for the practitioner according to their technique.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAspiration beforehand:\u003c\/b\u003e after inserting the needle and before injecting, it is recommended to withdraw the plunger slightly to verify that the needle is not intravascular.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eImmediate blanching:\u003c\/b\u003e stop the injection and massage the area until normal colour returns.\u003c\/li\u003e\n\u003cli\u003eInject slowly and with the minimum pressure necessary. If the needle becomes blocked, do not increase pressure on the plunger: stop the injection and replace the needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's annual limit:\u003c\/b\u003e no safety data are available for the injection of more than 20 ml of Allergan dermal fillers per 60 kg of body weight per year.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInterval between sessions:\u003c\/b\u003e wait for side effects to resolve, with a minimum interval of 2 weeks between two injections.\u003c\/li\u003e\n\u003cli\u003eDo not overcorrect: injecting an excessive volume may cause tissue necrosis and oedema.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e in the pivotal study registered with the FDA for this same 17.5 mg\/ml formulation with 0.3 % lidocaine (Juvéderm® VOLLURE™ XC, VYC-17.5L) in the nasolabial fold, with 123 subjects: 93.2 % responders at month 6 and 59.4 % at month 18 (improvement ≥ 1 point on the nasolabial fold severity scale). Usual total volume for optimal correction: 1.7 ml per treatment area; touch-ups require approximately one third of that volume.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAftercare:\u003c\/b\u003e no make-up for the following 12 hours; avoid prolonged exposure to the sun and to UV rays, temperatures below 0 °C, sauna and hammam for the following two weeks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAllergan Aesthetics \/ AbbVie — Route de Promery, Zone Artisanale de Pré-Mairy, Pringy, 74370 Annecy (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles manufactured by\u003c\/th\u003e\u003ctd\u003eTSK Laboratory, Tochigi (Japan)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid of non-animal origin, 17.5 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking agent\u003c\/th\u003e\u003ctd\u003eBDDE in trace amounts (\u0026lt; 2 ppm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBuffer\u003c\/th\u003e\u003ctd\u003ePhosphate, pH 7.2\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eVYCROSS®\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 graduated pre-filled syringes of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 × 30G ½\" (accepted cannulas of 25G, 27G and 30G)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute \/ plane\u003c\/th\u003e\u003ctd\u003eDeep dermis or labial mucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III implantable medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals with specific training in injection techniques only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C. Fragile product. Do not use after the expiry date stated on the label.\u003c\/li\u003e\n\u003cli\u003eDo not use the syringe if the contents show signs of separation or a cloudy appearance.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise: sterility cannot be guaranteed after reuse.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterilisation:\u003c\/b\u003e syringe contents by moist heat; needles by irradiation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 2 pre-filled syringes of 1.0 ml, 4 sterile needles of 30G ½\", instruction leaflet and a set of traceability labels.\u003c\/li\u003e\n\u003cli\u003eUsed needles must be disposed of in appropriate containers; never straighten a bent needle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e untreated epilepsy; tendency to hypertrophic scarring; known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins (the HA is obtained from bacteria of the genus \u003ci\u003eStreptococcus\u003c\/i\u003e); hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; pregnancy and breastfeeding; minors. Do not inject into areas with inflammatory or infectious skin processes (acne, herpes). Do not inject intravascularly. Do not overcorrect.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIncompatibilities:\u003c\/b\u003e hyaluronic acid is incompatible with quaternary ammonium salts such as benzalkonium chloride; avoid all contact with these substances or with instruments treated with them. No interactions with other local anaesthetics are known.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e there are no clinical data on efficacy and tolerance in patients with autoimmune disease, immunodeficiency or immunosuppressive therapy, nor in patients with a history of severe or multiple allergies — the indication is assessed case by case and a prior skin test is recommended; in case of a history of anaphylactic shock, it is recommended not to inject. Patients with a history of streptococcal disease (recurrent pharyngitis, acute rheumatic fever) should undergo a prior skin test. Warn patients on anticoagulant or antiplatelet therapy of the increased risk of bleeding and bruising. Because of the presence of lidocaine, combination with drugs that reduce or inhibit hepatic metabolism (cimetidine, beta blockers) is not recommended, and caution is advised in patients with cardiac conduction disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDo not use simultaneously\u003c\/b\u003e with laser, deep chemical peels or dermabrasion. With superficial peels, do not inject if the inflammatory reaction generated is significant.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e serious adverse events have been reported in association with intravascular injection of facial dermal fillers — temporary or permanent visual impairment, blindness, cerebral ischaemia or haemorrhage with stroke, skin necrosis and injury to underlying structures. Stop the injection immediately in the event of any visual change, sign of stroke, skin pallor or unusual pain.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Juvéderm® VOLIFT® with lidocaine (Allergan Aesthetics \/ AbbVie) and, where indicated, on FDA approval dossiers and peer-reviewed scientific literature. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Allergan","offers":[{"title":"Default Title","offer_id":51007631032660,"sku":"JUV007","price":198.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/juvederm-volift-lidocaine_600x_a1c48735-5ef7-48cb-95d9-e72f6dd629dc.webp?v=1735927928"},{"product_id":"juvederm-volite","title":"Juvederm Volite 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJuvéderm® VOLITE™ with lidocaine is the skin quality treatment from Allergan Aesthetics: cross-linked hyaluronic acid with VYCROSS® technology at 12 mg\/ml, the lowest concentration in the Juvéderm® range, formulated for intradermal injection with a 32G needle. It is not a volumiser: its documented purpose is the filling of superficial cutaneous depressions and the improvement of skin quality attributes such as hydration and elasticity. Allergan markets this same formulation under the designation SKINVIVE™ by Juvéderm®.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 12 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 × 32G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eHydration\u003c\/b\u003e maintained up to 9 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid gel:\u003c\/b\u003e 12.0 mg per ml, of non-animal origin. The lowest concentration in the entire Juvéderm® range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3.0 mg per ml (0.3 %), included to reduce patient pain during treatment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.2 q.s. to 1 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking agent:\u003c\/b\u003e butanediol diglycidyl ether (BDDE) in trace amounts (\u0026lt; 2 ppm).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVYCROSS® technology:\u003c\/b\u003e VOLITE™ corresponds to the VYC-12 gel of the VYCROSS® platform, which combines high- and low-molecular-weight hyaluronic acid. The low concentration and high cross-linking efficiency produce a very fluid gel with low water uptake, designed to be placed in intradermal microdeposits without a volumising effect.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eVOLITE™ is the only product in the Juvéderm® range that does not aim at volumetric correction. Its place in the clinic is before or alongside the fillers, not instead of them.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 2\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid dermis · medium-sized depressions and lip definition\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 3\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · mid and\/or deep dermis · medium and deep depressions, lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 4\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · deep dermis · deep depressions, lip augmentation and cheekbone augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA SMILE\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid and\/or deep dermis · lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003e\u003cb\u003eSKINVIVE™ by Juvéderm® (formerly VOLITE™) — this product\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA 12 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · intradermal · skin quality: hydration, elasticity, fine lines\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLBELLA®\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · superficial\/mid dermis and labial mucosa · fine lines, lips and infraorbital region\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLIFT®\u003c\/th\u003e\u003ctd\u003eHA 17.5 mg\/ml · VYCROSS® · 2 × 1 ml · 30G½\" · deep dermis or labial mucosa · deep depressions, facial contouring, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUMA®\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous, supraperiosteal or deep dermis · facial volume restoration\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUX™\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous and supraperiosteal · restoring and creating volume (chin and jawline)\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003eNote on the designation:\u003c\/b\u003e Allergan Aesthetics markets this same formulation — VYCROSS® hyaluronic acid 12 mg\/ml with 3 mg\/ml lidocaine, 2 syringes of 1 ml and 4 needles of 32G ½\" — under the name SKINVIVE™ by Juvéderm®, the designation with which the company has unified the brand globally since 2023-2025. VOLITE™ and SKINVIVE™ are not two different products: they are the same reference at two stages of nomenclature.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWhen to choose VOLITE™ over its neighbours:\u003c\/b\u003e compared with VOLBELLA® (15 mg\/ml), when there is no depression to be filled but rather a deficit in hydration, elasticity and texture, and when treatment is planned over a broad surface using microdeposits rather than at specific points. Compared with the ULTRA gels (24 mg\/ml), the difference is one of category: VOLITE™ provides neither projection nor structural support.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable implant indicated for the treatment, by filling, of superficial cutaneous depressions such as fine lines, and for the additional improvement of skin quality attributes such as hydration and elasticity.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFine lines and superficial cutaneous depressions\u003c\/li\u003e\n\u003cli\u003eSkin hydration and elasticity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eAreas studied:\u003c\/b\u003e according to the manufacturer, the efficacy and safety of VOLITE™ have been clinically studied only in the face and neck.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindicated areas:\u003c\/b\u003e do not inject into the eyelids. It is not indicated for breast augmentation or reconstruction.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eRoute of administration:\u003c\/b\u003e intradermal injection only.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 4 units of 32G ½\", sterilised by irradiation. The manufacturer accepts the TSK 32G 3\/16\" needle (ref. PRE-32004) as an alternative.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e separate intradermal microdeposits, distributed evenly over the area to be treated. The area must be disinfected in its entirety before treatment; in treatments over a broad surface, the complete area should be considered (for example, the whole face).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLimit per session:\u003c\/b\u003e the manufacturer states that the injection of a volume greater than 8.0 ml of VOLITE™ per treatment session has not been studied.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAspiration beforehand:\u003c\/b\u003e after inserting the needle and before injecting, it is recommended to withdraw the plunger slightly to verify that the needle is not intravascular.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eImmediate blanching:\u003c\/b\u003e stop the injection and massage the area until normal colour returns.\u003c\/li\u003e\n\u003cli\u003eInject slowly and with the minimum pressure necessary. If the needle becomes blocked, do not increase pressure on the plunger: stop the injection and replace the needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's annual limit:\u003c\/b\u003e no safety data are available for the injection of more than 20 ml of Allergan dermal fillers per 60 kg of body weight per year.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInterval between sessions:\u003c\/b\u003e wait for side effects to resolve, with a minimum interval of 2 weeks between two injections.\u003c\/li\u003e\n\u003cli\u003eDo not overcorrect: injecting an excessive volume may cause tissue necrosis and oedema.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e prospective study of the VYC-12 gel with 131 subjects treated by intradermal microdeposits with a 32G needle (median total volume 3.9 ml): 96.2 % responders in skin roughness (ASRS scale) at month 1 and 76.3 % at month 4; significant improvement in skin hydration maintained up to month 9 (Niforos F. et al., \u003ci\u003eClin Cosmet Investig Dermatol\u003c\/i\u003e 2019;12:791–798).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAftercare:\u003c\/b\u003e no make-up for the following 12 hours; avoid prolonged exposure to the sun and to UV rays, temperatures below 0 °C, sauna and hammam for the following two weeks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAllergan Aesthetics \/ AbbVie — Route de Promery, Zone Artisanale de Pré-Mairy, Pringy, 74370 Annecy (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles manufactured by\u003c\/th\u003e\u003ctd\u003eTSK Laboratory, Tochigi (Japan)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid of non-animal origin, 12.0 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3.0 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking agent\u003c\/th\u003e\u003ctd\u003eBDDE in trace amounts (\u0026lt; 2 ppm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBuffer\u003c\/th\u003e\u003ctd\u003ePhosphate, pH 7.2\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eVYCROSS® (VYC-12 gel)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 graduated pre-filled syringes of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 × 32G ½\" (alternative: TSK 32G 3\/16\")\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute \/ plane\u003c\/th\u003e\u003ctd\u003eIntradermal — microdeposits\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEquivalent designation\u003c\/th\u003e\u003ctd\u003eSKINVIVE™ by Juvéderm® (same formulation)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III implantable medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals with specific training in injection techniques only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C. Fragile product. Do not use after the expiry date stated on the label.\u003c\/li\u003e\n\u003cli\u003eDo not use the syringe if the contents show signs of separation or a cloudy appearance.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise: sterility cannot be guaranteed after reuse.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterilisation:\u003c\/b\u003e syringe contents by moist heat; needles by irradiation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 2 pre-filled syringes of 1.0 ml, 4 sterile needles of 32G ½\", instruction leaflet and a set of traceability labels.\u003c\/li\u003e\n\u003cli\u003eUsed needles must be disposed of in appropriate containers; never straighten a bent needle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e untreated epilepsy; tendency to hypertrophic scarring; known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins (the HA is obtained from bacteria of the genus \u003ci\u003eStreptococcus\u003c\/i\u003e); hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; pregnancy and breastfeeding; minors. Do not inject into areas with inflammatory or infectious skin processes (acne, herpes). Do not inject intravascularly. Do not overcorrect.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIncompatibilities:\u003c\/b\u003e hyaluronic acid is incompatible with quaternary ammonium salts such as benzalkonium chloride; avoid all contact with these substances or with instruments treated with them. No interactions with other local anaesthetics are known.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e there are no clinical data on efficacy and tolerance in patients with autoimmune disease, immunodeficiency or immunosuppressive therapy, nor in patients with a history of severe or multiple allergies — the indication is assessed case by case and a prior skin test is recommended; in case of a history of anaphylactic shock, it is recommended not to inject. Patients with a history of streptococcal disease (recurrent pharyngitis, acute rheumatic fever) should undergo a prior skin test. Warn patients on anticoagulant or antiplatelet therapy of the increased risk of bleeding and bruising. Because of the presence of lidocaine, combination with drugs that reduce or inhibit hepatic metabolism (cimetidine, beta blockers) is not recommended, and caution is advised in patients with cardiac conduction disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDo not use simultaneously\u003c\/b\u003e with laser, deep chemical peels or dermabrasion. With superficial peels, do not inject if the inflammatory reaction generated is significant.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e serious adverse events have been reported in association with intravascular injection of facial dermal fillers — temporary or permanent visual impairment, blindness, cerebral ischaemia or haemorrhage with stroke, skin necrosis and injury to underlying structures. Stop the injection immediately in the event of any visual change, sign of stroke, skin pallor or unusual pain.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Juvéderm® VOLITE™ \/ SKINVIVE™ by Juvéderm® (Allergan Aesthetics \/ AbbVie) and, where indicated, on FDA approval dossiers and peer-reviewed scientific literature. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Allergan","offers":[{"title":"Default Title","offer_id":51007631393108,"sku":"JUV008","price":212.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/juvederm_volite.jpg?v=1747758173"},{"product_id":"juvederm-voluma","title":"Juvederm Voluma 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJuvéderm® VOLUMA® with lidocaine is the reference filler from Allergan Aesthetics for volumetric restoration of the middle facial third. Its cross-linked hyaluronic acid gel with VYCROSS™ technology combines high projection capacity with predictable tissue integration and a documented duration of up to 24 months in clinical study.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 × 27G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e up to 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, cross-linking agent BDDE.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride monohydrate:\u003c\/b\u003e 3 mg\/ml, to reduce discomfort during injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.2 q.s. to 1 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVYCROSS™ technology:\u003c\/b\u003e a combination of low- and high-molecular-weight hyaluronic acid. The greater cross-linking efficiency allows a lower total HA concentration while maintaining duration, with a gel of homogeneous texture and lower water uptake, which translates into reduced post-treatment swelling.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G' of approximately 260–380 Pa depending on methodology (data from independent literature; Allergan does not publish official rheological values). High projection capacity with relatively low cohesivity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable implant indicated for the restoration of facial volume in patients aged 18 years and over.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCheekbones and malar region\u003c\/li\u003e\n\u003cli\u003eZygomatic region and projection of the middle third\u003c\/li\u003e\n\u003cli\u003eChin and definition of the facial contour\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eIt must not be injected\u003c\/b\u003e into the periorbital region (eyelid, tear trough, crow's feet), the glabella or the lips.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eManufacturer's dose limits:\u003c\/b\u003e maximum 2 ml per treatment area and session; maximum 20 ml of Allergan fillers per 60 kg of body weight per year.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis, subcutaneous tissue or supraperiosteal plane, depending on the area treated.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 4 units of 27G ½\", sterilised by irradiation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAspiration and retrograde injection\u003c\/b\u003e in accordance with standard clinical protocol to minimise vascular risk.\u003c\/li\u003e\n\u003cli\u003eNever inject intravascularly. Do not apply in areas with permanent implants.\u003c\/li\u003e\n\u003cli\u003eDo not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e 96 % responders at 8 weeks and 81.7 % at 78 weeks (Callan P. et al., \u003ci\u003eClin Cosmet Investig Dermatol\u003c\/i\u003e 2013;6:81–9). FDA pivotal study: 67.1 % responders at 24 months.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAllergan Aesthetics \/ AbbVie — Annecy, France\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 20 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking agent\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eVYCROSS™\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.2 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 × 27G ½\"\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the packaging.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 2 pre-filled syringes of 1.0 ml, 4 needles 27G ½\", instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e pregnancy and breastfeeding; uncontrolled epilepsy; tendency to hypertrophic or keloid scarring; known allergy to hyaluronic acid or to Gram-positive bacterial proteins; allergy to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area (acne, herpes); minors.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e autoimmune disease or immunosuppression; history of rheumatic fever or streptococcal infection; heart disease; severe or multiple allergies (previous anaphylaxis contraindicates treatment); anticoagulant or antiplatelet therapy; treatment with cimetidine or beta blockers because of the lidocaine.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (Juvéderm VOLUMA instructions for use, Allergan Aesthetics\/AbbVie) and on peer-reviewed scientific literature. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Allergan","offers":[{"title":"Default Title","offer_id":51007631851860,"sku":"JUV009","price":208.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/juvederm_voluma.jpg?v=1747764980"},{"product_id":"juvederm-volux","title":"Juvederm Volux 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJuvéderm® VOLUX™ is the most highly concentrated gel in the whole Allergan Aesthetics range: cross-linked hyaluronic acid with VYCROSS® technology at 25 mg\/ml with lidocaine, indicated for restoring and creating facial volume by subcutaneous and supraperiosteal injection. It is the only product in the line whose indication includes the creation of volume — not only its restoration — and its clinical development focuses on the chin and the mandibular angle.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 25 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 × 27G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eJawline\u003c\/b\u003e 61.3 % responders at 12 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid gel:\u003c\/b\u003e 25 mg per ml, of non-animal origin. The highest concentration in the Juvéderm® range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg per ml (0.3 %), included to reduce patient pain during treatment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.2 q.s. to 1 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking agent:\u003c\/b\u003e butanediol diglycidyl ether (BDDE) in trace amounts (\u0026lt; 2 ppm).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVYCROSS® technology:\u003c\/b\u003e a combination of high- and low-molecular-weight hyaluronic acid. In VOLUX™ the platform is taken to its maximum concentration to obtain a gel of high firmness, capable of supporting projected bony structures in the supraperiosteal plane while maintaining the low water uptake characteristic of VYCROSS®.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eVOLUX™ is the structural extreme of the range: maximum HA concentration and an exclusively deep injection plane. It is not a dermal product and its package insert allows no superficial intradermal indication.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 2\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid dermis · medium-sized depressions and lip definition\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 3\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · mid and\/or deep dermis · medium and deep depressions, lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 4\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · deep dermis · deep depressions, lip augmentation and cheekbone augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA SMILE\u003c\/th\u003e\u003ctd\u003eHA 24 mg\/ml · HYLACROSS™ · 2 × 0.55 ml · 30G½\" · mid and\/or deep dermis · lip definition and augmentation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSKINVIVE™ by Juvéderm® (formerly VOLITE™)\u003c\/th\u003e\u003ctd\u003eHA 12 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · intradermal · skin quality: hydration, elasticity, fine lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLBELLA®\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml · VYCROSS® · 2 × 1 ml · 32G½\" · superficial\/mid dermis and labial mucosa · fine lines, lips and infraorbital region\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLIFT®\u003c\/th\u003e\u003ctd\u003eHA 17.5 mg\/ml · VYCROSS® · 2 × 1 ml · 30G½\" · deep dermis or labial mucosa · deep depressions, facial contouring, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUMA®\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous, supraperiosteal or deep dermis · facial volume restoration\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003e\u003cb\u003eJuvéderm® VOLUX™ — this product\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA 25 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous and supraperiosteal · restoring and creating volume (chin and jawline)\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003eWhen to choose VOLUX™ over its neighbours:\u003c\/b\u003e compared with VOLUMA® (20 mg\/ml), when the aim is to define and project the mandibular border or the chin rather than to restore volume in the middle third: the indication of VOLUMA® is to restore facial volume, that of VOLUX™ is to restore \u003ci\u003eand create\u003c\/i\u003e volume, and its clinical development has been carried out in the chin and jawline. Compared with ULTRA 4 (24 mg\/ml, HYLACROSS™), when the work is supraperiosteal and not intradermal. Both products share the 27G ½\" needle and the 2 ml limit per area and session.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable implant indicated for restoring and creating facial volume.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eChin and chin projection\u003c\/li\u003e\n\u003cli\u003eJawline and mandibular angle\u003c\/li\u003e\n\u003cli\u003eDefinition of the facial contour in the deep plane\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eScope of the clinical data:\u003c\/b\u003e the manufacturer states that clinical trials with VOLUX™ have been carried out in the chin and jawline; there are no controlled clinical data for other anatomical regions.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindicated areas:\u003c\/b\u003e periorbital region (eyelid, tear trough area, crow's feet), glabellar region and lips. Intramuscular injection is not recommended. It is not indicated for breast augmentation or reconstruction.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e subcutaneous and supraperiosteal only. Technique and depth vary according to the area to be treated.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 4 units of 27G ½\", sterilised by irradiation, for exclusive use with this product.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCannula accepted by the manufacturer:\u003c\/b\u003e 25G × 38 mm cannula (ref. PRC-25038ISG-020S, STERiGLIDE \/ STERiJECT). The contraindications, method of use, precautions and warnings defined for the needle also apply to this cannula.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's dose limit:\u003c\/b\u003e do not inject more than 2 ml per treatment area in each session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAspiration beforehand:\u003c\/b\u003e after inserting the needle and before injecting, it is recommended to withdraw the plunger slightly to verify that the needle is not intravascular.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eImmediate blanching:\u003c\/b\u003e stop the injection and massage the area until normal colour returns.\u003c\/li\u003e\n\u003cli\u003eInject slowly and with the minimum pressure necessary. If the needle becomes blocked, do not increase pressure on the plunger: stop the injection and replace the needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's annual limit:\u003c\/b\u003e no safety data are available for the injection of more than 20 ml of Allergan dermal fillers per 60 kg of body weight per year.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInterval between sessions:\u003c\/b\u003e wait for side effects to resolve, with a minimum interval of 2 weeks between two injections.\u003c\/li\u003e\n\u003cli\u003eDo not overcorrect: injecting an excessive volume may cause tissue necrosis and oedema.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e in the pivotal study registered with the FDA for this same 25 mg\/ml formulation with 0.3 % lidocaine (Juvéderm® VOLUX™ XC) in loss of jawline definition: 69.9 % responders at month 6 and 61.3 % at month 12 (improvement ≥ 1 point on the Allergan jawline definition loss scale). Median total volume injected in initial treatment plus touch-up: 6.8 ml; maintenance: 3.0 ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAftercare:\u003c\/b\u003e no make-up for the following 12 hours; avoid prolonged exposure to the sun and to UV rays, temperatures below 0 °C, sauna and hammam for the following two weeks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eAllergan Aesthetics \/ AbbVie — Route de Promery, Zone Artisanale de Pré-Mairy, Pringy, 74370 Annecy (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles manufactured by\u003c\/th\u003e\u003ctd\u003eTSK Laboratory, Tochigi (Japan)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid of non-animal origin, 25 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking agent\u003c\/th\u003e\u003ctd\u003eBDDE in trace amounts (\u0026lt; 2 ppm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBuffer\u003c\/th\u003e\u003ctd\u003ePhosphate, pH 7.2\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eVYCROSS®\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 graduated pre-filled syringes of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 × 27G ½\" (accepted cannula: 25G × 38 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute \/ plane\u003c\/th\u003e\u003ctd\u003eSubcutaneous and supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eMaximum dose per area\u003c\/th\u003e\u003ctd\u003e2 ml per treatment area and session\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III implantable medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals with specific training in injection techniques only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C. Fragile product. Do not use after the expiry date stated on the label.\u003c\/li\u003e\n\u003cli\u003eDo not use the syringe if the contents show signs of separation or a cloudy appearance.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise: sterility cannot be guaranteed after reuse.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterilisation:\u003c\/b\u003e syringe contents by moist heat; needles by irradiation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 2 pre-filled syringes of 1.0 ml, 4 sterile needles of 27G ½\", instruction leaflet and a set of traceability labels.\u003c\/li\u003e\n\u003cli\u003eUsed needles must be disposed of in appropriate containers; never straighten a bent needle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e untreated epilepsy; tendency to hypertrophic scarring; known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins (the HA is obtained from bacteria of the genus \u003ci\u003eStreptococcus\u003c\/i\u003e); hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; pregnancy and breastfeeding; minors. Do not inject into areas with inflammatory or infectious skin processes (acne, herpes). Do not inject intravascularly. Do not overcorrect.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIncompatibilities:\u003c\/b\u003e hyaluronic acid is incompatible with quaternary ammonium salts such as benzalkonium chloride; avoid all contact with these substances or with instruments treated with them. No interactions with other local anaesthetics are known.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e there are no clinical data on efficacy and tolerance in patients with autoimmune disease, immunodeficiency or immunosuppressive therapy, nor in patients with a history of severe or multiple allergies — the indication is assessed case by case and a prior skin test is recommended; in case of a history of anaphylactic shock, it is recommended not to inject. Patients with a history of streptococcal disease (recurrent pharyngitis, acute rheumatic fever) should undergo a prior skin test. Warn patients on anticoagulant or antiplatelet therapy of the increased risk of bleeding and bruising. Because of the presence of lidocaine, combination with drugs that reduce or inhibit hepatic metabolism (cimetidine, beta blockers) is not recommended, and caution is advised in patients with cardiac conduction disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDo not use simultaneously\u003c\/b\u003e with laser, deep chemical peels or dermabrasion. With superficial peels, do not inject if the inflammatory reaction generated is significant.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e serious adverse events have been reported in association with intravascular injection of facial dermal fillers — temporary or permanent visual impairment, blindness, cerebral ischaemia or haemorrhage with stroke, skin necrosis and injury to underlying structures. Stop the injection immediately in the event of any visual change, sign of stroke, skin pallor or unusual pain.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Juvéderm® VOLUX™ (Allergan Aesthetics \/ AbbVie) and, where indicated, on FDA approval dossiers and peer-reviewed scientific literature. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Allergan","offers":[{"title":"Default Title","offer_id":51007632212308,"sku":"JUV010","price":208.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/juvederm_volux.jpg?v=1747764825"},{"product_id":"harmonyca-2x1ml","title":"HarmonyCA Lidocaine 2x1.25ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eHArmonyCa™ Lidocaine is the hybrid implant from Allergan Aesthetics: calcium hydroxyapatite microspheres at 55.7 % suspended in a cross-linked sodium hyaluronate gel at 20 mg\/ml, with lidocaine. It combines the immediate volumising effect of hyaluronic acid with the neocollagenesis associated with calcium hydroxyapatite. It is indicated for the augmentation of facial soft tissue in the deep dermal and subdermal plane and is supplied in 1.25 ml syringes.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCaHA\u003c\/b\u003e 55.7 % (microspheres of 25–45 µm)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 % w\/v)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 1.25 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\" thin-wall\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eSynthetic calcium hydroxyapatite (CaHA) microspheres:\u003c\/b\u003e concentration of 55.7 %, with a diameter of 25 to 45 microns.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linked sodium hyaluronate gel:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, acting as the suspension vehicle for the microspheres.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml (0.3 % w\/v), to reduce pain during treatment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003eSterile, pyrogen-free, viscous, opaque, semi-solid, biodegradable and latex-free dermal implant, in a graduated pre-filled 1.25 ml glass syringe.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDual mechanism of action:\u003c\/b\u003e the hyaluronic acid component provides the immediate lifting effect; the calcium hydroxyapatite component generates a sustained effect through the production of new collagen. According to data reported by the manufacturer, an increase in tissue density, viscoelasticity and firmness was observed at 60 days, confirmed at 90 days, and an increase in collagen in the treated areas was confirmed at 180 days after treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePositioning relative to the Juvéderm® range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eHArmonyCa™ does not belong to the Juvéderm® range and does not share its rationale: Juvéderm® gels are pure hyaluronic acid and their effect is exclusively that of a resorbable filler; HArmonyCa™ is a hybrid product whose calcium hydroxyapatite component adds a biological collagen stimulus.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003e\u003cb\u003eHArmonyCa™ Lidocaine — this product\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHybrid: CaHA 55.7 % + cross-linked HA 20 mg\/ml · 2 × 1.25 ml · 27G½\" thin-wall · deep dermis and subdermal · facial soft tissue augmentation with immediate lifting effect and neocollagenesis\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUX™\u003c\/th\u003e\u003ctd\u003ePure HA 25 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous and supraperiosteal · restoring and creating volume (chin and jawline)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLUMA®\u003c\/th\u003e\u003ctd\u003ePure HA 20 mg\/ml · VYCROSS® · 2 × 1 ml · 27G½\" · subcutaneous, supraperiosteal or deep dermis · facial volume restoration\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® VOLIFT®\u003c\/th\u003e\u003ctd\u003ePure HA 17.5 mg\/ml · VYCROSS® · 2 × 1 ml · 30G½\" · deep dermis or labial mucosa · deep depressions and facial contouring\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJuvéderm® ULTRA 4\u003c\/th\u003e\u003ctd\u003ePure HA 24 mg\/ml · HYLACROSS™ · 2 × 1 ml · 27G½\" · deep dermis · deep depressions, lips and cheekbones\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003ePractical differences to bear in mind:\u003c\/b\u003e unlike the Juvéderm® gels, the mineral component of HArmonyCa™ is not reversible with hyaluronidase; its contraindications are considerably broader (autoimmune diseases, diabetes not evaluated, patients treated with substances that prolong bleeding) and expressly exclude the lips and perioral region, as well as the glabella and periocular area. The minimum interval between sessions is seven days, and a minimum of four weeks must be observed with respect to ultrasound, laser or peeling treatments.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eDermal filler intended for the augmentation of facial soft tissue, to be injected into the deep dermal and subdermal layers.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eFacial regions excluded by the manufacturer:\u003c\/b\u003e glabellar and periocular area; lips and perioral region; epidermis and superficial dermis; regions containing foreign bodies; blood vessels and highly vascularised areas.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSpecific precaution:\u003c\/b\u003e take particular care when injecting into the marionette lines and the oral commissures; do not overcorrect, in order to avoid migration of material towards the lips.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 units of 27G ½\" thin-wall, sterile and single use. If a replacement is required, the manufacturer recommends 25G or 27G thin-wall needles; for multiple injections it recommends 27G thin-wall. Needles of smaller diameter increase the frequency of occlusion, while those of larger diameter increase adverse effects from puncture.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAngle and plane:\u003c\/b\u003e insert the needle at an angle of approximately 30° towards the deep dermis, with the bevel facing down to minimise deposition in more superficial planes. Palpate the region with the free hand to confirm the layer of insertion.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde threading — inject while applying gentle continuous pressure on the plunger as the needle is slowly withdrawn, forming a uniform thread. For deep folds, overlay several parallel threads beneath the fold; if larger volumes are required, place successive layers with the threads perpendicular to those of the layer below (\u003ci\u003ecross hatching\u003c\/i\u003e technique).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAspirate beforehand\u003c\/b\u003e to verify that injection is not being made into a vessel. If blanching occurs, stop the injection and massage until colour recovers; if it does not recover, do not resume the injection.\u003c\/li\u003e\n\u003cli\u003eStop injecting before withdrawing the needle to avoid leakage of gel into superficial layers. Do not overcorrect. Gently massage the treated area on completion to distribute the gel and adapt it to the contour.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInterval between sessions:\u003c\/b\u003e a minimum of seven days between treatments, to allow effective assessment of the result. Maintain at least four weeks' separation from ultrasound, laser or peeling treatments.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAftercare:\u003c\/b\u003e no make-up on the area for the 12 hours before and after; avoid intense physical activity, sun exposure, tanning lamps and extreme weather conditions for 24 hours; apply local cold for 24 hours. Reactions at the treatment site usually resolve within 24–48 hours and oedema within one week. The patient should be aware that the injected material may remain palpable for a prolonged period.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eMarketed by\u003c\/th\u003e\u003ctd\u003eAllergan Aesthetics \/ AbbVie\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer (syringe)\u003c\/th\u003e\u003ctd\u003ePanaxia LTD, 13 Hamelacha St., Lod 7152026 (Israel)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer (needle)\u003c\/th\u003e\u003ctd\u003eTSK Laboratory, Tochigi (Japan)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAuthorised representative\u003c\/th\u003e\u003ctd\u003eMedNet EC-REP III GmbH, Münster (Germany)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredients\u003c\/th\u003e\u003ctd\u003eCalcium hydroxyapatite microspheres 55.7 % (25–45 µm) + cross-linked sodium hyaluronate 20 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 % w\/v)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExcipient\u003c\/th\u003e\u003ctd\u003ePhosphate buffer\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled graduated glass syringes of 1.25 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\" thin-wall\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute \/ plane\u003c\/th\u003e\u003ctd\u003eDeep dermal and subdermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eSyringe fluid path by steam; needle by irradiation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked pre-filled syringe in accordance with Directive 93\/42\/EEC, notified body 2409; CE-marked needle, notified body 0123\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eLatex\u003c\/th\u003e\u003ctd\u003eContains no detectable latex\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eAuthorised healthcare professionals only, single use and single patient\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from light. Avoid prolonged exposure to elevated temperatures. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date printed on the packaging. Do not use if the packaging is open or has been tampered with.\u003c\/li\u003e\n\u003cli\u003eDo not use if damage to the device is suspected (cracked or broken syringe barrel, open cap or plunger). Discard any damaged device.\u003c\/li\u003e\n\u003cli\u003eHArmonyCa™ Lidocaine is a homogeneous gel: inspect it before injecting and do not use it if particles, discolouration or signs of separation are observed.\u003c\/li\u003e\n\u003cli\u003eSingle-use, single-patient product. Do not re-sterilise. Only the fluid path and the contents of the syringe are sterile. A new needle must be used for each syringe.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 2 pre-filled syringes of 1.25 ml and 2 sterile single-use needles of 27G ½\" thin-wall.\u003c\/li\u003e\n\u003cli\u003eAll used devices must be treated as a potential biohazard and disposed of in accordance with applicable regulations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to any of the components; skin disease or skin disorders; acute or chronic infection or inflammation in or near the treatment area; predisposition to keloids, hypertrophic scarring or development of inflammatory dermatoses; healing compromised by systemic disorders, medication or poorly vascularised tissue; prolonged bleeding or delayed healing due to disease or medication; history of anaphylactic reactions or multiple severe allergies; known sensitivity to corticosteroids or contraindication to their use; presence of herpes; autoimmune diseases; pregnancy and breastfeeding; patients under 18 years of age; hypersensitivity to lidocaine or to other amide-type local anaesthetics and any condition in which lidocaine is contraindicated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindicated areas:\u003c\/b\u003e glabellar and periocular area; lips and perioral region; regions with foreign bodies; blood vessels and highly vascularised areas; epidermis and superficial dermis.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject into blood vessels — aspiration before injection is recommended; intravascular introduction may cause occlusion, ischaemia, infarction and necrosis of local or distant tissues. Do not use in areas with inflammatory reaction, infection or tumour. Safety and efficacy have not been evaluated in patients with a history of keloids, connective tissue disease, active bleeding disorders, active hepatitis, clinically significant abnormal laboratory findings, cancer, a history of stroke or myocardial infarction, nor in patients on immunosuppressive therapy, patients treated with other filler implants, nor in diabetic patients. Safety has not been evaluated after dilution of the product or in combination with epilation, UV radiation, laser or mechanical or chemical peelings. It must not be used in patients treated with substances that prolong bleeding (acetylsalicylic acid, anticoagulants, thrombolytics, anti-inflammatories, ACE inhibitors). Do not inject into tissue that may be damaged by the volumising properties of a filler, nor through scar tissue, cartilage or compromised, infected or inflamed tissue. Do not over-inject.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIncompatibility:\u003c\/b\u003e hyaluronic acid and quaternary ammonium salts (for example, benzalkonium chloride) are incompatible; all contact must be avoided.\u003c\/p\u003e\n\u003cp\u003eSome adverse events may require surgical intervention, including drainage of haematomas or seromas and removal of the implant in cases of severe allergy, inflammation, hypersensitivity or infection.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of HArmonyCa™ Lidocaine (Allergan Aesthetics \/ AbbVie, June 2024 revision) and on the manufacturer's product documentation. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Allergan","offers":[{"title":"Default Title","offer_id":51007632376148,"sku":"HAR001","price":260.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Allergan-HArmonyCa_600x_5cfdced8-14ce-4319-b61f-73df8209d1ff.webp?v=1735927919"},{"product_id":"restylane-defyne","title":"Restylane Defyne 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Defyne is the firmest gel in Galderma's OBT™ family: with an elastic modulus of 271 Pa and a deformability of 761 %, it supports deep folds without losing the flexibility that allows facial movement. It is formulated for severe wrinkles and folds \u0026mdash; nasolabial fold and marionette lines \u0026mdash; where a NASHA gel would be too rigid.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnology\u003c\/b\u003e OBT™ \/ XpresHAn™\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\u0026quot; UTW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, cross-linked with BDDE and suspended in phosphate buffer solution at pH 7.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml, to reduce discomfort during injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOBT™ technology (Optimal Balance Technology):\u003c\/b\u003e unlike NASHA gels, which are particulate and minimally cross-linked, OBT modulates the degree of cross-linking to obtain a continuous, soft and deformable gel. Defyne is the variant with the highest degree of cross-linking within OBT.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G\u0026prime; 271 Pa at 0.1 Hz and deformability (xStrain) of 761 %. It is the highest firmness value and the lowest flexibility value of the OBT family: maximum support within a gel that still follows facial expression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two different gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low tolerance to deformation: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, called \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the US market): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high tolerance to deformation: the gel follows the movement of the tissue, so it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, mid third of the face, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, without volumetric purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values come from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjection into the mid to deep dermis for the correction of severe facial wrinkles and folds.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNasolabial fold\u003c\/li\u003e\n\u003cli\u003eMarionette lines\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCompared with Restylane Refyne (G\u0026prime; 70 Pa), indicated for moderate wrinkles, Defyne is reserved for deeper defects that require more structural support.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 units of 27G ½\u0026quot; ultra-thin wall (UTW).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde threading, serial puncture or a combination of both, with low, constant injection pressure.\u003c\/li\u003e\n\u003cli\u003ePrior aspiration in accordance with standard clinical protocol to minimise vascular risk.\u003c\/li\u003e\n\u003cli\u003eDo not combine in the same session with laser treatment, deep peeling or dermabrasion.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e in the pivotal study submitted to the FDA, 77.1 % of subjects maintained an improvement at 6 months and 69.7 % at one year, measured with the WSRS (\u003ci\u003eWrinkle Severity Rating Scale\u003c\/i\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 20 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eOBT™ (XpresHAn Technology™)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVehicle \/ pH\u003c\/th\u003e\u003ctd\u003ePhosphate buffer solution, pH 7\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheology\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 271 Pa \u0026middot; deformability 761 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\u0026quot; ultra-thin wall\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 27G ½\u0026quot; UTW, instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of an anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e coagulation disorders or anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); history of hypertrophic or keloid scarring; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection can cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbance, blindness or stroke. Aspiration before injecting and low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (Restylane® Defyne™ instructions for use, Q-Med AB \/ Galderma). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007633293652,"sku":"RES001","price":86.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/restylane_defyne_9ad0a8db-16e9-4bf7-88f0-1b2ddf7839c5.jpg?v=1775491905"},{"product_id":"restylane-lidocaina","title":"Restylane Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane with lidocaine is Galderma's original gel and the reference product for NASHA® technology: stabilised hyaluronic acid of non-animal origin, particulate, with minimal cross-linking. With a G\u0026prime; of 701 Pa and a deformability of barely 7 %, it is a firm, minimally deformable gel, intended for wrinkles in the mid dermis and for lips where definition rather than movement is sought.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eStabilised HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnology\u003c\/b\u003e NASHA®\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 29G TW ½\u0026quot;\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStabilised hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin (produced by bacterial fermentation), suspended in phosphate buffer solution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml, included to reduce discomfort during treatment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNASHA® technology\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): the process preserves the long, natural chains of hyaluronic acid and applies a minimal degree of cross-linking. The result is a particulate, firm gel with little tolerance to deformation \u0026mdash; the conceptual opposite of the OBT family.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G\u0026prime; 701 Pa at 0.1 Hz and deformability (xStrain) of 7 %, the lowest value in the entire Restylane range. This rigidity is precisely what allows the definition of edges and contours.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNote on the name:\u003c\/b\u003e in several European markets the product is now marketed as \u003ci\u003eRestylane® Classyc™ Lidocaine\u003c\/i\u003e. It is the same formulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two different gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low tolerance to deformation: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, called \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the US market): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high tolerance to deformation: the gel follows the movement of the tissue, so it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, mid third of the face, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, without volumetric purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values come from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eFacial tissue augmentation: correction of wrinkles and lip enhancement.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFacial wrinkles and folds \u0026mdash; mid dermis\u003c\/li\u003e\n\u003cli\u003eLips \u0026mdash; volume and definition of the vermilion border\u003c\/li\u003e\n\u003cli\u003eMid third of the face and jawline in deeper planes, where tissue support is adequate\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid dermis for facial wrinkles; submucosal plane in the lips; subcutaneous or supraperiosteal plane in the mid third of the face and the jawline.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles:\u003c\/b\u003e 29G thin wall (TW) or 30G, ½\u0026quot;. Blunt cannulas of 27\u0026ndash;28G may be used as an alternative.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde threading or serial puncture, with low, constant pressure. Because of its particulate, firm character, the NASHA gel is deposited more locally and requires less shaping massage than an OBT gel.\u003c\/li\u003e\n\u003cli\u003ePrior aspiration in accordance with standard clinical protocol to minimise vascular risk.\u003c\/li\u003e\n\u003cli\u003eAvoid superficial injection: it can produce contour irregularities or bluish discoloration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eStabilised hyaluronic acid 20 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eNASHA®\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVehicle\u003c\/th\u003e\u003ctd\u003ePhosphate buffer solution\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheology\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 701 Pa \u0026middot; deformability 7 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 glass syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e29G TW ½\u0026quot; or 30G ½\u0026quot; (alternative: 27\u0026ndash;28G blunt cannula)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eMid dermis; submucosal in the lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight. No refrigeration required.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 glass syringe of 1.0 ml, sterile needle, instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of an anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e coagulation disorders or anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); history of hypertrophic or keloid scarring; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection can cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbance, blindness or stroke. Aspiration before injecting and low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (Restylane® \/ Restylane® Classyc™ Lidocaine instructions for use, Q-Med AB \/ Galderma). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007633686868,"sku":"RES004","price":84.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Classic.jpg?v=1775491905"},{"product_id":"restylane-lyft","title":"Restylane Lyft Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Lyft with lidocaine is the firmest NASHA® gel in the Galderma range: G\u0026prime; of 799 Pa with a deformability of 17 %. It is formulated to restore volume and projection in the mid third of the face and is the only product in the line with a documented indication for the dorsum of the hands, in addition to the correction of deep folds.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eStabilised HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnology\u003c\/b\u003e NASHA®\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 29G TW ½\u0026quot;\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStabilised hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, cross-linked with BDDE and suspended in phosphate buffer solution at pH 7.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml (0.3 %).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNASHA® technology:\u003c\/b\u003e large-particle particulate gel, the largest particle size in the NASHA family. The combination of minimal cross-linking and large particle size is what generates the lifting capacity.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G\u0026prime; 799 Pa at 0.1 Hz, the highest firmness value in the entire Restylane range, with a deformability of 17 %. Maximum projection per millilitre; in return, it is not a gel for areas of intense facial expression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two different gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low tolerance to deformation: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, called \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the US market): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high tolerance to deformation: the gel follows the movement of the tissue, so it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, mid third of the face, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, without volumetric purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values come from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCheekbones and mid third of the face:\u003c\/b\u003e malar augmentation and correction of the contour deficit of the mid third \u0026mdash; subcutaneous to supraperiosteal plane.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eModerate to severe facial folds and wrinkles\u003c\/b\u003e (nasolabial fold) \u0026mdash; deep dermis to superficial subcutaneous tissue.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDorsum of the hands:\u003c\/b\u003e correction of the volume deficit \u0026mdash; subcutaneous plane.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eMaximum volumes per session\u003c\/b\u003e according to the registration documentation: 6.0 ml in facial folds, 6.0 ml in malar augmentation and 3.0 ml per hand.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e according to the area \u0026mdash; deep dermis or superficial subcutis in folds; subcutaneous to supraperiosteal in the mid third of the face; subcutaneous on the dorsum of the hands.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 29G thin wall (TW) ½\u0026quot;, the one used in the registration studies.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e supraperiosteal bolus deposit or linear retrograde threading, according to the area. On the dorsum of the hand, pinch and lift the tissue before injecting in order to remain in the subcutaneous plane.\u003c\/li\u003e\n\u003cli\u003ePrior aspiration in accordance with standard clinical protocol. The mid third of the face is an area of significant vascular risk.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e according to Galderma's patient information, in nasolabial wrinkles 96 % of subjects showed an improvement at 12 weeks and 79 % at 48 weeks; in malar volume, around 90 % at 2 months and more than 50 % at one year. Efficacy and safety beyond one year have not been investigated in a clinical trial.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eStabilised hyaluronic acid 20 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eNASHA® \u0026mdash; large particle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVehicle \/ pH\u003c\/th\u003e\u003ctd\u003ePhosphate buffer solution, pH 7\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheology\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 799 Pa \u0026middot; deformability 17 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e29G TW ½\u0026quot;\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eDeep dermis, subcutaneous or supraperiosteal according to the area\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, sterile needle(s) 29G TW ½\u0026quot;, instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of an anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions and individual assessment:\u003c\/b\u003e coagulation disorders or anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); history of hypertrophic or keloid scarring; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection can cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbance, blindness or stroke. Aspiration before injecting and low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (Restylane® Lyft™ with lidocaine instructions for use and patient information, Q-Med AB \/ Galderma). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007634080084,"sku":"RES005","price":86.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Lyft.jpg?v=1775491906"},{"product_id":"11970","title":"Restylane Skinboosters Vital Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Skinboosters Vital with lidocaine is Galderma's hydration biostimulator: NASHA® stabilised hyaluronic acid at 20 mg\/ml delivered as dermal microdeposits, not as a volumetric filler. Its purpose is skin quality \u0026mdash; smoothness, elasticity and skin appearance \u0026mdash; and it works with its own protocol of three sessions plus maintenance.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eStabilised HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 29G TW\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3 sessions \/ 4 weeks\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStabilised hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml (0.3 %).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNASHA® technology:\u003c\/b\u003e the Skinbooster uses the NASHA gel with the smallest particle size in the family. Stabilised \u0026mdash; unlike a free hyaluronic acid used in mesotherapy \u0026mdash; which prolongs its residence in the dermis and allows the sessions to be spaced further apart.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDifference from the fillers in the range:\u003c\/b\u003e Vital is not formulated to project or to correct folds. It is deposited in a distributed manner in the dermis to improve hydration and elasticity, not to create volume.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSmart Click system:\u003c\/b\u003e glass syringe with click dosing, allowing deposits of reproducible volume in the multi-puncture technique.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two distinct gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that preserve the long hyaluronic acid chains with minimal cross-linking. High resistance and very low tolerance to deformation: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, known as \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the US market): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high tolerance to deformation: the gel follows the movement of the tissue, so it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, midface, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, without volumetric purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values are taken from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eImprovement of the smoothness, appearance and elasticity of the skin.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLower facial third and jawline\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese are the areas documented in the manufacturer's instructions for use. Use on the neck, décolletage or other areas falls outside the indication and is the responsibility of the practitioner who indicates it.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e dermis, preferably its deep portion.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle included:\u003c\/b\u003e 29G thin wall (TW), disposable. As an alternative, a 30G blunt cannula may be used, creating an entry point beforehand.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits (multi-puncture), with slow injection and minimal pressure.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInitial protocol:\u003c\/b\u003e 3 sessions separated by 4 weeks.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMaintenance:\u003c\/b\u003e one session every 6 months.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's dose limits:\u003c\/b\u003e maximum 5 ml per session and 20 ml per patient per year.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eDistinction from Vital Light:\u003c\/b\u003e Vital is concentrated at 20 mg\/ml and is deposited in the deep dermis; Vital Light is concentrated at 12 mg\/ml and is deposited in the mid dermis, for thinner skin and more subtle results.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eStabilised hyaluronic acid 20 mg\/ml, of non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml (0.3 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eNASHA® \u0026mdash; small particle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 glass syringe of 1.0 ml with Smart Click system\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e29G TW (alternative: 30G blunt cannula)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eDermis, preferably deep\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003e3 sessions every 4 weeks; maintenance every 6 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eMaximum dose\u003c\/th\u003e\u003ctd\u003e5 ml per session \u0026middot; 20 ml per patient per year\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 glass syringe of 1.0 ml with Smart Click system, disposable 29G TW needle, instructions for use and traceability label for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; coagulation disorders; history of keloid scarring; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e anticoagulant or antiplatelet therapy (greater risk of haematoma and bleeding at the puncture site); autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection may cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbances, blindness or stroke. Aspiration before injecting and low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (instructions for use Restylane® Skinboosters™ Vital Lidocaine, Q-Med AB \/ Galderma). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007634440532,"sku":"RES007","price":74.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Skinboosters_Vital.jpg?v=1775491905"},{"product_id":"restylane-refyne","title":"Restylane Refyne 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Refyne is the softest and most deformable gel in the entire Galderma range: G\u0026prime; of 70 Pa and a strain tolerance of 1,442 %. This combination makes it suitable for \u003cb\u003emoderate\u003c\/b\u003e wrinkles and folds in areas of marked facial expression, where the aim is that the filler should not be perceptible when speaking or smiling. For severe folds, the indicated variant is Defyne.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnology\u003c\/b\u003e OBT™ \/ XpresHAn™\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\u0026quot; UTW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, cross-linked with BDDE in phosphate buffer solution at pH 7.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOBT™ technology (Optimal Balance Technology):\u003c\/b\u003e a continuous, non-particulate gel obtained with the lowest degree of cross-linking in the family. Refyne is the soft end of the range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G\u0026prime; 70 Pa at 0.1 Hz \u0026mdash; compared with 701 Pa for classic Restylane NASHA \u0026mdash; and a deformability (xStrain) of 1,442 %, the highest in the range. It is the gel that allows itself to be deformed most by the tissue before recovering its shape.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two distinct gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low strain tolerance: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, marketed as \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the United States): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high strain tolerance: the gel follows the movement of the tissue, which is why it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, midface, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, with no volumising purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values are taken from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjection into the mid to deep dermis for the correction of \u003cb\u003emoderate\u003c\/b\u003e facial wrinkles and folds.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNasolabial sulcus (nasolabial folds) of moderate depth\u003c\/li\u003e\n\u003cli\u003eSuperficial to medium expression lines in areas of high mobility\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eDistinction from Defyne:\u003c\/b\u003e Refyne is documented for moderate wrinkles; severe folds are the domain of Defyne (G\u0026prime; 271 Pa). Using Refyne in a severe fold usually results in undercorrection.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 units of 30G ½\u0026quot; ultra-thin wall. Alternatively, a 27G blunt cannula may be used.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde injection or serial puncture, with low and constant pressure.\u003c\/li\u003e\n\u003cli\u003eAspiration prior to injection in accordance with standard clinical protocol to minimise vascular risk.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDocumented duration:\u003c\/b\u003e in the pivotal study submitted to the FDA, 78.8 % of subjects maintained an improvement at 6 months and 62.3 % at one year, measured with the WSRS scale.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 20 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eOBT™ (XpresHAn Technology™)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVehicle \/ pH\u003c\/th\u003e\u003ctd\u003ePhosphate buffer solution, pH 7\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheology\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70 Pa \u0026middot; deformability 1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\u0026quot; ultra-thin wall (alternative: 27G blunt cannula)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 30G ½\u0026quot; UTW, instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e coagulation disorders or anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); history of hypertrophic or keloid scarring; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection may cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbances, blindness or stroke. Aspiration before injecting and a low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (instructions for use Restylane® Refyne™, Q-Med AB \/ Galderma). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007634669908,"sku":"RES006","price":88.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Refyne.jpg?v=1775491905"},{"product_id":"restylane-vital-light-lidocaina","title":"Restylane Skinboosters Vital Light Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Skinboosters Vital Light with lidocaine is the light variant of the Galderma Skinbooster: 12 mg\/ml of NASHA® stabilised hyaluronic acid compared with the 20 mg\/ml of Vital. It is deposited in the mid dermis and is intended for thin skin and for subtle results, with a shorter three-session protocol and a lower dose limit than Vital.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eStabilised HA\u003c\/b\u003e 12 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 29G TW\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3 sessions \/ 2\u0026ndash;4 weeks\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStabilised hyaluronic acid:\u003c\/b\u003e 12 mg\/ml, of non-animal origin. This is the differentiating element compared with Vital (20 mg\/ml).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml, the same concentration as in Vital.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNASHA® technology:\u003c\/b\u003e small-particle stabilised hyaluronic acid. The lower concentration results in a more fluid gel, which distributes more readily in the mid dermis and in skin of lesser thickness.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePurpose:\u003c\/b\u003e skin hydration and elasticity. It is not a volumising product and is not formulated to correct folds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two distinct gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low strain tolerance: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, marketed as \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the United States): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high strain tolerance: the gel follows the movement of the tissue, which is why it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, midface, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, with no volumising purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values are taken from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eImprovement of skin elasticity.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLower facial third and jawline\u003c\/li\u003e\n\u003cli\u003eUpper cervical region\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese are the areas documented in the manufacturer's instructions for use. Use on the décolleté, dorsum of the hands or other areas falls outside the indication and is the responsibility of the practitioner who prescribes it.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid dermis \u0026mdash; more superficial than Vital, which is deposited in the deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle included:\u003c\/b\u003e 29G thin wall (TW), disposable. Alternatively, a sterile 30G blunt cannula may be used, with the side port oriented downwards.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits with slow injection and minimal pressure.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInitial protocol:\u003c\/b\u003e 3 sessions 2 to 4 weeks apart.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMaintenance:\u003c\/b\u003e one session every 4 to 6 months.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturer's dose limits:\u003c\/b\u003e maximum 3.5 ml per session and 17.5 ml per patient per year (Vital: 5 ml and 20 ml respectively).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eStabilised hyaluronic acid 12 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eNASHA® \u0026mdash; small particle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 glass syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e29G TW (alternative: 30G blunt cannula)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eMid dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003e3 sessions every 2\u0026ndash;4 weeks; maintenance every 4\u0026ndash;6 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eMaximum dose\u003c\/th\u003e\u003ctd\u003e3.5 ml per session \u0026middot; 17.5 ml per patient per year\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 glass syringe of 1.0 ml with finger grip and plunger rod, disposable 29G TW needle, instructions for use and a traceability label for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; coagulation disorders; history of keloid scarring; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection may cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbances, blindness or stroke. Aspiration before injecting and a low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (instructions for use Restylane® Skinboosters™ Vital Light Lidocaine, Q-Med AB \/ Galderma). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007634866516,"sku":"RES008","price":72.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Skinboosters_Vital_Light.jpg?v=1775491905"},{"product_id":"11976","title":"Stylage Hydro Max 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSTYLAGE\u0026reg; HydroMax is the injectable revitaliser from Laboratoires VIVACY for improving skin hydration and elasticity: 12.5 mg of BDDE cross-linked hyaluronic acid per gram of gel. Unlike the rest of the STYLAGE range, it is not formulated with mannitol but with \u003cb\u003esorbitol as the moisturising agent\u003c\/b\u003e. It is injected into the mid to deep dermis of the face, neck, décolletage and dorsum of the hand.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 12.5 mg\/g (BDDE)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eActive excipient\u003c\/b\u003e Sorbitol (moisturising agent)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe \u0026times; 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 sterile single-use\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 1 to 3 sessions\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid (BDDE):\u003c\/b\u003e 12.5 mg.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer and sorbitol,\u003c\/b\u003e pH 7.2, q.s. to 1 g of gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSorbitol, not mannitol:\u003c\/b\u003e the instructions for use describe STYLAGE\u0026reg; HydroMax as a cross-linked hyaluronic acid gel incorporating \u003cb\u003ea moisturising agent (sorbitol)\u003c\/b\u003e. It is the only reference in the range that does not contain mannitol as an antioxidant. This difference in formulation has a direct clinical consequence: HydroMax is contraindicated in patients with fructose intolerance.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDifference from STYLAGE\u0026reg; Hydro:\u003c\/b\u003e Hydro is a \u003ci\u003ereinforced\u003c\/i\u003e hyaluronic acid gel (14 mg\/g) with mannitol, indicated at the dermo-epidermal junction and in the superficial dermis. HydroMax is a \u003ci\u003ecross-linked\u003c\/i\u003e gel (12.5 mg\/g) with sorbitol, indicated in the mid to deep dermis. They are not interchangeable.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eIPN-Like technology (InterPenetrated Networks):\u003c\/b\u003e VIVACY's patented cross-linking technology. It preserves the partial independence of the interpenetrated hyaluronic acid networks while increasing the density of chemical nodes. The manufacturer associates it with the optimisation of the gel's rheology — in particular the viscosity, to ensure injectability — and with the cohesivity and monophasic character of the gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e BDDE. Hyaluronic acid of non-animal origin.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBi-SOFT\u0026reg; syringe:\u003c\/b\u003e patented bi-material injection system (polycarbonate and thermoplastic elastomer with a soft-touch surface), with oversized plunger and finger flanges and an optimised centre of gravity. It is a property of the syringe, not of the gel: it aims to reduce the perceived injection force and improve control of the deposit.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterile, non-pyrogenic gel,\u003c\/b\u003e of physiological pH and osmolarity, packaged in a pre-filled syringe and sterilised by autoclave (moist heat). The needles are sterilised by irradiation or ethylene oxide.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the variants of the STYLAGE\u0026reg; range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe range is graded by hyaluronic acid concentration and degree of cross-linking, which determines\nthe consistency of the gel and, with it, the injection plane and the indication. The concentrations\nare taken from the manufacturer's instructions for use and are expressed per gram of gel (q.s. to 1 g).\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eS\u0026nbsp;\u0026mdash; 16 mg\/g\u003c\/th\u003e\u003ctd\u003eSuperficial to mid dermis. Cutaneous depressions of the face; lip definition by injection into the mucosa. 0.8 ml syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eM\u0026nbsp;\u0026mdash; 20 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Cutaneous depressions; lip definition and\/or volume augmentation; restoration of volume on the dorsum of the hand by the subcutaneous route\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eL\u0026nbsp;\u0026mdash; 24 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis. Cutaneous depressions of the face. Not indicated for superficial wrinkles or for thin skin, lips or areas with an exposed vascular network\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXL\u0026nbsp;\u0026mdash; 26 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. Restoration or augmentation of facial volumes. It is the highest concentration in the range\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXXL\u0026nbsp;\u0026mdash; 21 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. High-viscosity volumising; the only one in the range whose pack includes a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSpecial Lips\u0026nbsp;\u0026mdash; 18.5 mg\/g\u003c\/th\u003e\u003ctd\u003eLabial mucosa. Redefinition and\/or augmentation of lip volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydroMax\u0026nbsp;\u0026mdash; 12.5 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Skin hydration and elasticity. The only one in the range formulated with sorbitol instead of mannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe concentration of XXL is lower than that of XL: the range is not a linear ascending scale. XL and XXL\nshare a volumising indication and injection plane, and differ in the rheological behaviour\nof the gel \u0026mdash; the manufacturer positions XXL as a high-viscosity volumiser.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid gel indicated to improve skin hydration and elasticity by injection into the mid to deep dermis.\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFace\u003c\/li\u003e\u003cli\u003eNeck\u003c\/li\u003e\u003cli\u003eDécolletage\u003c\/li\u003e\u003cli\u003eDorsum of the hand\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eIt is not a volumetric filler or a wrinkle-correction product: its purpose according to the instructions for use is the rehydration and reinforcement of skin elasticity.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended techniques:\u003c\/b\u003e nappage, papules or a combination of both.\u003c\/li\u003e\n\u003cli\u003eThe practitioner must select the needle of appropriate length according to the area treated, the type of correction sought and the technique chosen, from those supplied.\u003c\/li\u003e\n\u003cli\u003eOnly the needles supplied with the product should be used: the combination of both devices has been validated by the manufacturer. Screw the needle firmly onto the Luer-Lock cone.\u003c\/li\u003e\n\u003cli\u003eDo not inject too deeply: this would reduce the efficacy of the revitalisation. An injection that is too superficial may cause discolouration or small indurations.\u003c\/li\u003e\n\u003cli\u003eThe amount to be injected depends on the area treated and on the level of dehydration of the skin.\u003c\/li\u003e\n\u003cli\u003eIt is recommended not to inject more than 20 ml of cross-linked hyaluronic acid per person per year (all ranges combined).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSessions:\u003c\/b\u003e depending on the patient's skin and the depth of injection, one to three sessions are required for optimal treatment. Regular touch-up sessions maintain the result.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e do not apply cold and massage the treated area thoroughly to optimise the uniformity of the correction.\u003c\/li\u003e\n\u003cli\u003eAdvise the patient to massage the area thoroughly in the days following the injection, especially if the micropapule technique has been used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eLaboratoires VIVACY, Archamps Technopole, 74160 Archamps (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 12.5 mg\/g\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive excipient\u003c\/th\u003e\u003ctd\u003eSorbitol (moisturising agent) \u0026mdash; contains no mannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eIPN-Like (cross-linking) \u0026middot; Bi-SOFT\u0026reg; syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.2 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 sterile single-use needles (gauge not specified in the instructions for use)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking in accordance with Directive 93\/42\/EEC; notified body 0344. According to the instructions for use, STYLAGE\u0026reg; HydroMax obtained CE marking in 2009\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTraceability\u003c\/th\u003e\u003ctd\u003eVIVACY remote authentication system with RFID technology\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e in its original packaging between 2 \u0026deg;C and 25 \u0026deg;C, protected from freezing and from light. Failure to comply with the storage conditions may affect the performance of the product.\u003c\/li\u003e\n\u003cli\u003eIf it has been kept in a refrigerator, allow the product to reach room temperature before injection.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging and on the syringe. Do not use if the packaging is damaged.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or resterilise, even if the implant has not been injected. Inject immediately after opening.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 sterile single-use needles, instructions for use and labels with the batch number \u0026mdash; one for the patient and one for the medical record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eMust not be used:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ein combination with a peel, a laser treatment or dermabrasion (the practitioner decides the waiting period required after these treatments)\u003c\/li\u003e\n\u003cli\u003ein patients with a tendency to develop hypertrophic scars\u003c\/li\u003e\n\u003cli\u003ein patients with known hypersensitivity to any of the components\u003c\/li\u003e\n\u003cli\u003ein pregnant or breastfeeding women, or in children\u003c\/li\u003e\n\u003cli\u003ein areas or in the vicinity of areas with inflammatory or infectious skin problems (acne, herpes, etc.)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ein patients with fructose intolerance\u003c\/b\u003e (contraindication specific to HydroMax because of its sorbitol content)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003ePrecautions for use:\u003c\/b\u003e it is strongly recommended to obtain the patient's informed consent. In patients with a history of herpes, the punctures may trigger a new outbreak. In patients with declared autoimmune disease or a history thereof, the practitioner must decide on a case-by-case basis, propose a prior double test and not inject if the disease is progressive. Patients with a history of streptococcal disease (recurrent tonsillitis, rheumatic fever) must undergo a prior double test; in the case of rheumatic fever with cardiac involvement, injection is not recommended. In the case of a haemostatic disorder or anticoagulant therapy, the risk of haematoma is increased. The intake of aspirin, NSAIDs, antiplatelet agents, anticoagulants or vitamin C should be avoided in the week before injection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e do not inject into blood vessels. Accidental intravascular injection may cause vascular occlusion with rare but serious complications — visual disturbances, blindness, necrosis of the skin and\/or of the underlying tissues — depending on the area injected. Do not inject into nerves: accidental nerve injury may cause transient paraesthesia.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Laboratoires VIVACY (OPDC342 v4) and on the manufacturer's technical documentation. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Vivacy","offers":[{"title":"Default Title","offer_id":51007635095892,"sku":"STY001","price":62.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Stylage-Bi-Soft-Hydromax_600x_55b79d9e-a610-4c44-98c4-5bd71eb8a488.webp?v=1735927901"},{"product_id":"11984","title":"Stylage S Lidocaine 2x0.8ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSTYLAGE\u0026reg; S Lidocaine is the lowest-concentration filler in the Laboratoires VIVACY dermal filler range: 16 mg of BDDE cross-linked hyaluronic acid per gram of gel, with 3 mg of lidocaine hydrochloride. It is indicated for filling cutaneous depressions of the face by injection into the superficial to mid dermis and for lip definition by injection into the labial mucosa. Like the whole STYLAGE range, it incorporates mannitol as an antioxidant.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 16 mg\/g (BDDE)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/g\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 0.8 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 sterile single-use\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e Superficial to mid dermis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid (BDDE):\u003c\/b\u003e 16 mg.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg, intended to reduce the pain associated with injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer and mannitol,\u003c\/b\u003e pH 7.2, q.s. to 1 g of gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMannitol (antioxidant):\u003c\/b\u003e incorporated into the formulation as an antioxidant agent. According to VIVACY's technical documentation, it protects the hyaluronic acid gel against the damage caused by the free radicals (oxidative stress) generated during the injection process, thereby slowing the degradation of the hyaluronic acid. It is the differentiating element of the STYLAGE range compared with conventional HA fillers.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eIPN-Like technology (InterPenetrated Networks):\u003c\/b\u003e VIVACY's patented cross-linking technology. It preserves the partial independence of the interpenetrated hyaluronic acid networks while increasing the density of chemical nodes. The manufacturer associates it with the optimisation of the gel's rheology — in particular the viscosity, to ensure injectability — and with the cohesivity and monophasic character of the gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e BDDE. Hyaluronic acid of non-animal origin.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBi-SOFT\u0026reg; syringe:\u003c\/b\u003e patented bi-material injection system (polycarbonate and thermoplastic elastomer with a soft-touch surface), with oversized plunger and finger flanges and an optimised centre of gravity. It is a property of the syringe, not of the gel: it aims to reduce the perceived injection force and improve control of the deposit.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterile, non-pyrogenic gel,\u003c\/b\u003e of physiological pH and osmolarity, packaged in a pre-filled syringe and sterilised by autoclave (moist heat). The needles are sterilised by irradiation or ethylene oxide.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the variants of the STYLAGE\u0026reg; range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe range is graded by hyaluronic acid concentration and degree of cross-linking, which determines\nthe consistency of the gel and, with it, the injection plane and the indication. The concentrations\nare taken from the manufacturer's instructions for use and are expressed per gram of gel (q.s. to 1 g).\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eS\u0026nbsp;\u0026mdash; 16 mg\/g\u003c\/th\u003e\u003ctd\u003eSuperficial to mid dermis. Cutaneous depressions of the face; lip definition by injection into the mucosa. 0.8 ml syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eM\u0026nbsp;\u0026mdash; 20 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Cutaneous depressions; lip definition and\/or volume augmentation; restoration of volume on the dorsum of the hand by the subcutaneous route\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eL\u0026nbsp;\u0026mdash; 24 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis. Cutaneous depressions of the face. Not indicated for superficial wrinkles or for thin skin, lips or areas with an exposed vascular network\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXL\u0026nbsp;\u0026mdash; 26 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. Restoration or augmentation of facial volumes. It is the highest concentration in the range\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXXL\u0026nbsp;\u0026mdash; 21 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. High-viscosity volumising; the only one in the range whose pack includes a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSpecial Lips\u0026nbsp;\u0026mdash; 18.5 mg\/g\u003c\/th\u003e\u003ctd\u003eLabial mucosa. Redefinition and\/or augmentation of lip volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydroMax\u0026nbsp;\u0026mdash; 12.5 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Skin hydration and elasticity. The only one in the range formulated with sorbitol instead of mannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe concentration of XXL is lower than that of XL: the range is not a linear ascending scale. XL and XXL\nshare a volumising indication and injection plane, and differ in the rheological behaviour\nof the gel \u0026mdash; the manufacturer positions XXL as a high-viscosity volumiser.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid gel intended to fill cutaneous depressions of the face by injection into the dermis. STYLAGE\u0026reg; S Lidocaine is equally indicated for the definition (\u003ci\u003eourlement\u003c\/i\u003e) of the lips by injection into the labial mucosa. The lidocaine hydrochloride is intended to reduce the pain associated with injection.\u003c\/p\u003e\u003cp\u003eBecause of its low consistency, it is the variant of the range intended for the finest and most superficial corrections within the authorised dermal range.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOutside the indication:\u003c\/b\u003e the instructions for use do not cover treatment of the tear trough, the periorbital region or the restoration of facial volumes, which correspond to other variants or fall outside the intended use of the range.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e superficial to mid dermis of the face; labial mucosa for lip definition.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended techniques:\u003c\/b\u003e retrograde linear injection, multi-puncture technique or a combination of both.\u003c\/li\u003e\n\u003cli\u003eOnly the needles supplied with the product should be used: the combination of both devices has been validated by the manufacturer. Screw the needle firmly onto the Luer-Lock cone.\u003c\/li\u003e\n\u003cli\u003eThe use of sterile CE-marked blunt-tip cannulas is possible. In that case the practitioner must select the appropriate gauge and length and scrupulously observe aseptic conditions, in particular the pre-hole.\u003c\/li\u003e\n\u003cli\u003eInject slowly to avoid overcorrection. If the injection is too deep, the efficacy of the correction is reduced; if it is too superficial, skin discolouration, small indurations or an irregular correction may appear.\u003c\/li\u003e\n\u003cli\u003eThe amount to be injected depends on the defect to be corrected and only the practitioner can define it. Do not overcorrect.\u003c\/li\u003e\n\u003cli\u003eIt is recommended not to inject more than 20 ml of cross-linked hyaluronic acid per person per year (all ranges combined).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSessions:\u003c\/b\u003e depending on the characteristics of the area, of the patient and of the depth of injection, one or two sessions are required for optimal treatment. Regular touch-up sessions allow the correction to be maintained.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e do not apply cold and massage the treated area thoroughly to optimise the uniformity of the correction.\u003c\/li\u003e\n\u003cli\u003eIn the event of increased pain during the injection, stop the procedure and withdraw the needle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eLaboratoires VIVACY, Archamps Technopole, 74160 Archamps (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 16 mg\/g\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/g\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAntioxidant\u003c\/th\u003e\u003ctd\u003eMannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eIPN-Like (cross-linking) \u0026middot; Bi-SOFT\u0026reg; syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.2 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 0.8 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 sterile single-use needles (gauge not specified in the instructions for use)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eSuperficial to mid dermis; labial mucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation or ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking in accordance with Directive 93\/42\/EEC; notified body 0344. According to the instructions for use, STYLAGE\u0026reg; S Lidocaine obtained CE marking in 2009\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTraceability\u003c\/th\u003e\u003ctd\u003eVIVACY remote authentication system with RFID technology\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e in its original packaging between 2 \u0026deg;C and 25 \u0026deg;C, protected from freezing and from light. Failure to comply with the storage conditions may affect the performance of the product.\u003c\/li\u003e\n\u003cli\u003eIf it has been kept in a refrigerator, allow the product to reach room temperature before injection.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging and on the syringe. Do not use if the packaging is damaged.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or resterilise, even if the implant has not been injected. Inject immediately after opening.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 0.8 ml, 4 sterile single-use needles, instructions for use and labels with the batch number \u0026mdash; one for the patient and one for the medical record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eMust not be used:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ein combination with a peel, a laser treatment or dermabrasion (the practitioner decides the waiting period required after these treatments)\u003c\/li\u003e\n\u003cli\u003ein patients with a tendency to develop hypertrophic scars\u003c\/li\u003e\n\u003cli\u003ein patients with known hypersensitivity to any of the components\u003c\/li\u003e\n\u003cli\u003ein pregnant or breastfeeding women, or in children\u003c\/li\u003e\n\u003cli\u003ein areas or in the vicinity of areas with inflammatory or infectious skin problems (acne, herpes, etc.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eIn addition, because of its lidocaine content,\u003c\/b\u003e it must not be used in patients with known hypersensitivity to amide-type local anaesthetics or in patients with porphyria. Combination with certain medicinal products that reduce or inhibit hepatic metabolism is not advised. Lidocaine hydrochloride may induce a positive reaction in anti-doping tests.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePrecautions for use:\u003c\/b\u003e it is strongly recommended to obtain the patient's informed consent. In patients with a history of herpes, the punctures may trigger a new outbreak. In patients with declared autoimmune disease or a history thereof, the practitioner must decide on a case-by-case basis, propose a prior double test and not inject if the disease is progressive. Patients with a history of streptococcal disease (recurrent tonsillitis, rheumatic fever) must undergo a prior double test; in the case of rheumatic fever with cardiac involvement, injection is not recommended. In the case of a haemostatic disorder or anticoagulant therapy, the risk of haematoma is increased. The intake of aspirin, NSAIDs, antiplatelet agents, anticoagulants or vitamin C should be avoided in the week before injection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e do not inject into blood vessels. Accidental intravascular injection may cause vascular occlusion with rare but serious complications — visual disturbances, blindness, necrosis of the skin and\/or of the underlying tissues — depending on the area injected. Do not inject into nerves: accidental nerve injury may cause transient paraesthesia.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Laboratoires VIVACY (OPDC340 v4) and on the manufacturer's technical documentation. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Vivacy","offers":[{"title":"Default Title","offer_id":51007635587412,"sku":"STY006","price":88.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/stylage_s.jpg?v=1747753268"},{"product_id":"teosyal-rha-1","title":"Teosyal RHA 1 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eTeosyal RHA\u0026reg; 1 is the most fluid reference of Teoxane's Resilient Hyaluronic Acid range: 15 mg\/ml of hyaluronic acid with a degree of cross-linking below 5 %, formulated for superficial fine lines and to improve skin quality in areas of constant animation. It is not a volumising product: its role within the range is superficial correction and sustained dermal hydration, with 0.3 % lidocaine incorporated.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 15 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e \u0026lt; 5 % (NMR)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 % (3 mg\/ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 \u0026times; 30G \u0026frac12;\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e \u0026ge; 12 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 15 mg\/ml \u0026mdash; the lowest concentration in the RHA range.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e \u0026lt; 5 %, measured by nuclear magnetic resonance.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 0.3 % by mass (3 mg\/ml).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eResidual BDDE:\u003c\/b\u003e \u0026lt; 1 ppm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.3 q.s. for 1 ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eRHA technology (Resilient Hyaluronic Acid):\u003c\/b\u003e Teoxane's patented manufacturing process (\u003ci\u003ePreserved Network Technology\u003c\/i\u003e) that applies minimal chemical modification and preserves the long hyaluronic acid chains. The result is a gel of low cross-linking (\u0026lt; 5 %) able to stretch and recover its shape with facial movement, instead of resisting it like a conventional rigid gel.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eBehaviour of the gel:\u003c\/b\u003e high malleability and specific viscoelastic properties that allow homogeneous distribution within the tissue, an optimal level of dermal hydration and a sustained improvement of skin elasticity.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Teosyal RHA range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eRHA 1 \u003cb\u003e(this product)\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; superficial fine lines and skin quality \u0026middot; \u0026ge; 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 2\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; moderate wrinkles, midface and lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 3\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; deep wrinkles, midface volume and remodelling of the lower third \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 4\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1.2 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; deep wrinkles in thick skin and remodelling of the facial contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA Kiss\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 0.7 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; perioral region and lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\u003cp\u003eAll references of the RHA range share a \u003cb\u003edegree of cross-linking below 5 %\u003c\/b\u003e, determined by nuclear magnetic resonance, and 0.3 % lidocaine. Within that margin the cross-linking increases in steps: RHA 2 is the least cross-linked, RHA 3 occupies an intermediate position and RHA 4 is the most cross-linked (FDA, \u003ci\u003eSummary of Safety and Effectiveness Data\u003c\/i\u003e P170002). That progression determines the firmness of the gel, the needle gauge supplied and the injection depth.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eTherapeutic indication:\u003c\/b\u003e correction of superficial fine wrinkles, skin creases and depressions in the perioral region, the upper third, the periorbital region, the midface and the lines of the neck.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAesthetic indication:\u003c\/b\u003e improvement of skin quality and correction of dull skin with signs of ageing on the face, neck and décolleté.\u003c\/p\u003e\u003cp\u003eBecause of its low concentration and its fluidity, RHA 1 is not intended for volume restoration or for lip augmentation; for those indications RHA 3, RHA 4 or RHA Kiss are the appropriate choices.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e at variable depth \u0026mdash; dermis, subcutaneous or supraperiosteal plane, according to the area. Do not inject into the epidermis.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 30G \u0026frac12;\", two per syringe (4 per pack).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eCannula:\u003c\/b\u003e as an alternative to the needle, a 25G blunt cannula may be used; the manufacturer has verified compatibility with the TSK 25G\/50 mm cannula.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eMaximum volume:\u003c\/b\u003e 6 ml per session. In the tear trough, a maximum of 0.5 ml per side.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eEstimated duration:\u003c\/b\u003e at least 12 months, varying with skin type, area treated, volume injected, and the patient's physiology and habits.\u003c\/li\u003e\u003cli\u003eDo not combine in the same session with peeling, laser or ultrasound.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eTeoxane SA (Laboratoires Teoxane), Geneva, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 15 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e\u0026lt; 5 % (NMR)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 0.3 % by mass\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE, residual \u0026lt; 1 ppm\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eRHA \u0026mdash; Resilient Hyaluronic Acid\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.3 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 \u0026times; 30G \u0026frac12;\" (2 per syringe)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCompatible cannula\u003c\/th\u003e\u003ctd\u003e25G (TSK 25G\/50 mm verified)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDermis, subcutaneous or supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEstimated duration\u003c\/th\u003e\u003ctd\u003eAt least 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 \u0026deg;C and 25 \u0026deg;C, protected from direct sunlight.\u003c\/li\u003e\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise the syringe or the needles.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 1 ml, 4 sterile 30G \u0026frac12;\" needles, and two traceability labels per syringe \u0026mdash; one to be given to the patient and one for the medical record.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e skin disorders, inflammation or infection in or near the treatment area; allergy to hyaluronic acid and a history of severe allergy or anaphylactic shock; allergy to lidocaine or to amide-type local anaesthetics; recent peel, laser or ultrasound treatment; autoimmune diseases; heart disease or treatment with beta-blockers; hepatocellular insufficiency or treatment for liver disease; epilepsy; porphyria; pregnancy, breastfeeding and patients under 18 years of age.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eVascular warning:\u003c\/b\u003e intravascular injection may cause vascular occlusion, ischaemia and necrosis of the treated area. In the most serious cases it may lead to visual disturbances or blindness and to cerebral ischaemia or haemorrhage. Never inject intravascularly.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBefore injection:\u003c\/b\u003e do not treat if a dental procedure has been performed in the previous 15 days; avoid aspirin, anti-inflammatory drugs, anticoagulants and vitamin E during the preceding week; avoid alcohol and intense sun exposure on the previous day and on the day itself; remove make-up completely.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e during the first 12 hours, do not apply make-up or undertake intense exertion; during the following week, avoid alcohol, prolonged sun or UV exposure, temperatures below 0 \u0026deg;C, sauna and hammam; for 15 days, do not undergo dental procedures or other aesthetic treatments.\u003c\/p\u003e\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Teoxane SA (instructions for use TEOSYAL RHA\u0026reg; 1, ref. 230578-00, and patient product information). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Teoxane","offers":[{"title":"Default Title","offer_id":51007636930900,"sku":"TEO008","price":128.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/teosyal_rha1.jpg?v=1747778435"},{"product_id":"teosyal-rha-3","title":"Teosyal RHA 3 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eTeosyal RHA\u0026reg; 3 occupies the intermediate position of the Resilient Hyaluronic Acid range: 23 mg\/ml of hyaluronic acid with cross-linking below 5 %, more cross-linked than RHA 2 and less than RHA 4. It is the versatile reference of the range \u0026mdash; deep wrinkles, midface volume and remodelling of the lower third \u0026mdash; and the first to be supplied with a 27G \u0026frac12;\" needle.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 23 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e \u0026lt; 5 % (NMR)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 % (3 mg\/ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 \u0026times; 27G \u0026frac12;\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 12\u0026ndash;18 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 23 mg\/ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e \u0026lt; 5 %, measured by nuclear magnetic resonance. \u003cb\u003eIntermediate\u003c\/b\u003e cross-linking within the RHA range, above RHA 2 and below RHA 4 (FDA, \u003ci\u003eSummary of Safety and Effectiveness Data\u003c\/i\u003e P170002).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 0.3 % by mass (3 mg\/ml).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eResidual BDDE:\u003c\/b\u003e \u0026lt; 1 ppm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.3 q.s. for 1 ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eRHA technology (Resilient Hyaluronic Acid):\u003c\/b\u003e Teoxane's patented manufacturing process (\u003ci\u003ePreserved Network Technology\u003c\/i\u003e) that applies minimal chemical modification and preserves the long hyaluronic acid chains. The result is a gel of low cross-linking (\u0026lt; 5 %) able to stretch and recover its shape with facial movement, instead of resisting it like a conventional rigid gel.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePractical consequence:\u003c\/b\u003e a gel with the capacity to sustain volume in the midface and to fill deep folds, while maintaining the adaptation to movement that characterises the range. The step up in gauge to 27G \u0026frac12;\" reflects that greater firmness.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Teosyal RHA range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eRHA 1\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; superficial fine lines and skin quality \u0026middot; \u0026ge; 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 2\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; moderate wrinkles, midface and lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 3 \u003cb\u003e(this product)\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; deep wrinkles, midface volume and remodelling of the lower third \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA 4\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 1.2 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; deep wrinkles in thick skin and remodelling of the facial contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRHA Kiss\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml \u0026middot; 0.7 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; perioral region and lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\u003cp\u003eAll references of the RHA range share a \u003cb\u003edegree of cross-linking below 5 %\u003c\/b\u003e, determined by nuclear magnetic resonance, and 0.3 % lidocaine. Within that margin the cross-linking increases in steps: RHA 2 is the least cross-linked, RHA 3 occupies an intermediate position and RHA 4 is the most cross-linked (FDA, \u003ci\u003eSummary of Safety and Effectiveness Data\u003c\/i\u003e P170002). That progression determines the firmness of the gel, the needle gauge supplied and the injection depth.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eTherapeutic indication:\u003c\/b\u003e reconstructive surgery, filling of scar depressions and reconstruction of volumes lost through lipoatrophy in patients under treatment for HIV.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAesthetic indication:\u003c\/b\u003e correction of deep facial wrinkles and marked skin folds, and provision of volume in:\u003c\/p\u003e\u003cul\u003e\u003cli\u003eMidface: nasolabial folds, cheekbones, nasojugal groove\u003c\/li\u003e\u003cli\u003eLower third: chin and jawline\u003c\/li\u003e\u003cli\u003ePerioral region: lips (including the philtrum), marionette lines, oral commissures\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e at variable depth \u0026mdash; dermis, subcutaneous plane, supraperiosteal, or subdermis and submucosa of the red lip.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 27G \u0026frac12;\", two per syringe (4 per pack).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eCannula:\u003c\/b\u003e a valid alternative is a 25G blunt cannula; compatibility verified by the manufacturer with TSK 25G\/50 mm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eMaximum volume:\u003c\/b\u003e 6 ml per session. In the lips a maximum of 2 ml is recommended.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eEstimated duration:\u003c\/b\u003e between 12 and 18 months.\u003c\/li\u003e\u003cli\u003eDo not inject into the epidermis. Do not combine in the same session with peeling, laser or ultrasound.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eTeoxane SA (Laboratoires Teoxane), Geneva, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 23 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e\u0026lt; 5 % (NMR) \u0026mdash; intermediate within the RHA range\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 0.3 % by mass\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE, residual \u0026lt; 1 ppm\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eRHA \u0026mdash; Resilient Hyaluronic Acid\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.3 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 \u0026times; 27G \u0026frac12;\" (2 per syringe)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCompatible cannula\u003c\/th\u003e\u003ctd\u003e25G (TSK 25G\/50 mm verified)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDermis, subcutaneous, supraperiosteal, subdermis or labial submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEstimated duration\u003c\/th\u003e\u003ctd\u003e12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 \u0026deg;C and 25 \u0026deg;C, protected from direct sunlight.\u003c\/li\u003e\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise the syringe or the needles.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 1 ml, 4 sterile 27G \u0026frac12;\" needles, and two traceability labels per syringe \u0026mdash; one to be given to the patient and one for the medical record.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e skin disorders, inflammation or infection in or near the treatment area; allergy to hyaluronic acid and a history of severe allergy or anaphylactic shock; allergy to lidocaine or to amide-type local anaesthetics; recent peel, laser or ultrasound treatment; autoimmune diseases; heart disease or treatment with beta-blockers; hepatocellular insufficiency or treatment for liver disease; epilepsy; porphyria; pregnancy, breastfeeding and patients under 18 years of age.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eVascular warning:\u003c\/b\u003e intravascular injection may cause vascular occlusion, ischaemia and necrosis of the treated area. In the most serious cases it may lead to visual disturbances or blindness and to cerebral ischaemia or haemorrhage. Never inject intravascularly.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBefore injection:\u003c\/b\u003e do not treat if a dental procedure has been performed in the previous 15 days; avoid aspirin, anti-inflammatory drugs, anticoagulants and vitamin E during the preceding week; avoid alcohol and intense sun exposure on the previous day and on the day itself; remove make-up completely.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e during the first 12 hours, do not apply make-up or undertake intense exertion; during the following week, avoid alcohol, prolonged sun or UV exposure, temperatures below 0 \u0026deg;C, sauna and hammam; for 15 days, do not undergo dental procedures or other aesthetic treatments.\u003c\/p\u003e\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Teoxane SA (instructions for use TEOSYAL RHA\u0026reg; 3, ref. 230581-00, and patient product information). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Teoxane","offers":[{"title":"Default Title","offer_id":51007637258580,"sku":"TEO010","price":138.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/teosyal_rha3.jpg?v=1747778133"},{"product_id":"teosyal-puresense-redensity","title":"Teosyal PureSense Redensity 1 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eTeosyal\u0026reg; PureSense Redensity 1 is Teoxane's skin redensifier and the only injectable product of the Teosyal range that is \u003cb\u003enot cross-linked\u003c\/b\u003e: 15 mg\/ml of hyaluronic acid of non-animal origin with an average molecular weight above 1 million daltons, formulated in a phosphate buffer supplemented with 8 amino acids, 3 antioxidants, vitamin B6 and 2 minerals. It provides no volume: it acts on the quality, hydration and elasticity of the skin.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 15 mg\/ml, non-cross-linked\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMolecular weight\u003c\/b\u003e \u0026gt; 1 million daltons\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 % (3 mg\/ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 \u0026times; 30G \u0026frac12;\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 2\u0026ndash;3 sessions + maintenance\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 15 mg\/ml, of non-animal origin, with an average molecular weight above 1 million daltons. As it is not cross-linked, it contains no BDDE.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 0.3 % by mass (3 mg\/ml).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eDermo-restructuring complex (supplemented phosphate buffer, pH 7.3):\u003c\/b\u003e the buffer is not inert, it incorporates the following active components:\u003cul\u003e\u003cli\u003e\u003cb\u003e3 antioxidants:\u003c\/b\u003e \u0026alpha;-lipoic acid, glutathione and N-acetyl-L-cysteine.\u003c\/li\u003e\u003cli\u003e\u003cb\u003e8 amino acids:\u003c\/b\u003e L-arginine, L-isoleucine, L-leucine, L-lysine monohydrate, glycine, L-valine, L-threonine and L-proline \u0026mdash; precursors for collagen and elastin synthesis.\u003c\/li\u003e\u003cli\u003e\u003cb\u003e1 vitamin:\u003c\/b\u003e pyridoxine (vitamin B6) in the form of the hydrochloride.\u003c\/li\u003e\u003cli\u003e\u003cb\u003e2 minerals:\u003c\/b\u003e zinc acetate dihydrate and copper sulphate pentahydrate, enzyme cofactors.\u003c\/li\u003e\u003cli\u003eSodium chloride.\u003c\/li\u003e\u003c\/ul\u003eThe manufacturer does not publish the individual concentrations of these components.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eBehaviour of the gel:\u003c\/b\u003e owing to its marked fluidity and its viscoelastic properties it distributes homogeneously within the tissue, which ensures an optimal level of hydration and a lasting improvement of skin texture and elasticity.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Teosyal PureSense range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 1 \u003cb\u003e(this product)\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eNon-cross-linked\u003c\/b\u003e HA 15 mg\/ml + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; skin quality and hydration \u0026middot; \u0026ge; 3 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 2\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml (cross-linking \u0026lt; 10 %) + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; periorbital region and tear trough \u0026middot; \u0026ge; 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eGlobal Action\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; wrinkles and skin depressions, lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDeep Lines\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; marked wrinkles and depressions \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eKiss\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; lips and perioral region \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltra Deep\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1.2 ml \u0026middot; 25G 1\" \u0026mdash; facial volume and contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltimate\u003c\/th\u003e\u003ctd\u003eHA 22 mg\/ml \u0026middot; 1 ml \u0026mdash; facial contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\u003cp\u003eThe cross-linked PureSense range declares a \u003cb\u003edegree of cross-linking below 10 %\u003c\/b\u003e (NMR), compared with the \u0026lt; 5 % of the RHA range. It is a firmer gel with a greater capacity for projection at an equal concentration; the RHA range instead prioritises adaptation to movement in areas of high facial animation. Redensity 1 falls outside this logic: it is not cross-linked and provides no volume.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eImprovement of skin quality and hydration and correction of dull skin with signs of ageing, as well as prevention of superficial fine wrinkles.\u003c\/p\u003e\u003cul\u003e\u003cli\u003eFace\u003c\/li\u003e\u003cli\u003eNeck\u003c\/li\u003e\u003cli\u003eDécolleté\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eRedensity 1 is not a volumising filler. Where the objective is to correct a fold or to restore volume, the cross-linked references of the range are the appropriate choice.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal or subcutaneous.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 30G \u0026frac12;\", two per syringe (4 per pack).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eCannula:\u003c\/b\u003e as an alternative to the needle, a 25G or 27G blunt cannula may be used; the manufacturer has verified compatibility with TSK 25G\/50 mm and TSK 27G\/38 mm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e 2 to 3 sessions at an interval of 3 or 4 weeks, followed by a maintenance session 2 or 3 times a year.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eMaximum volume:\u003c\/b\u003e 6 ml per session.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eEstimated duration:\u003c\/b\u003e at least 3 months \u0026mdash; hence the schedule of repeated sessions compared with the single session of a cross-linked filler.\u003c\/li\u003e\u003cli\u003eDo not inject into the epidermis. Do not combine in the same session with peeling, laser or ultrasound.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eTeoxane SA (Laboratoires Teoxane), Geneva, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid 15 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin of the HA\u003c\/th\u003e\u003ctd\u003eNon-animal, average molecular weight \u0026gt; 1 million daltons\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking\u003c\/th\u003e\u003ctd\u003eNone \u0026mdash; non-cross-linked product, without BDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 0.3 % by mass\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAssociated complex\u003c\/th\u003e\u003ctd\u003e8 amino acids, 3 antioxidants, vitamin B6, zinc and copper\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.3 (supplemented phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 \u0026times; 30G \u0026frac12;\" (2 per syringe)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCompatible cannula\u003c\/th\u003e\u003ctd\u003e25G (TSK 25G\/50 mm) or 27G (TSK 27G\/38 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eIntradermal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEstimated duration\u003c\/th\u003e\u003ctd\u003eAt least 3 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 \u0026deg;C and 25 \u0026deg;C, protected from direct sunlight.\u003c\/li\u003e\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise the syringe or the needles.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 1 ml, 4 sterile 30G \u0026frac12;\" needles, and two traceability labels per syringe \u0026mdash; one to be given to the patient and one for the medical record.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e skin disorders, inflammation or infection in or near the treatment area; allergy to hyaluronic acid and a history of severe allergy or anaphylactic shock; allergy to lidocaine or to amide-type local anaesthetics; recent peel, laser or ultrasound treatment; autoimmune diseases; heart disease or treatment with beta-blockers; hepatocellular insufficiency or treatment for liver disease; epilepsy; porphyria; pregnancy, breastfeeding and patients under 18 years of age.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eVascular warning:\u003c\/b\u003e intravascular injection may cause vascular occlusion, ischaemia and necrosis of the treated area. In the most serious cases it may lead to visual disturbances or blindness and to cerebral ischaemia or haemorrhage. Never inject intravascularly.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBefore injection:\u003c\/b\u003e do not treat if a dental procedure has been performed in the previous 15 days; avoid aspirin, anti-inflammatory drugs, anticoagulants and vitamin E during the preceding week; avoid alcohol and intense sun exposure on the previous day and on the day itself; remove make-up completely.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e during the first 12 hours, do not apply make-up or undertake intense exertion; during the following week, avoid alcohol, prolonged sun or UV exposure, temperatures below 0 \u0026deg;C, sauna and hammam; for 15 days, do not undergo dental procedures or other aesthetic treatments.\u003c\/p\u003e\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Teoxane SA (instructions for use TEOSYAL\u0026reg; PureSense REDENSITY 1, ref. 230586-00, and patient product information). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Teoxane","offers":[{"title":"Default Title","offer_id":51007637913940,"sku":"TEO004","price":86.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/teosyal_redensity_1.jpg?v=1747837833"},{"product_id":"teosyal-puresense-global-action","title":"Teosyal PureSense Global Action 2x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eTeosyal\u0026reg; PureSense Global Action is the versatile reference of the classic PureSense range: 25 mg\/ml of cross-linked hyaluronic acid with 0.3 % lidocaine, in 1 ml syringes. According to the manufacturer, it creates a volume that corrects wrinkles and skin depressions and restores skin hydration, and it can additionally add volume to the lip or enhance its contour.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 25 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 % (3 mg\/ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 12\u0026ndash;18 months\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRange\u003c\/b\u003e classic PureSense\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 25 mg\/ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 0.3 % by mass (3 mg\/ml), incorporated into the gel to reduce discomfort during injection.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e q.s. for 1 ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePerformance declared by the manufacturer:\u003c\/b\u003e it creates a volume that corrects wrinkles and skin depressions and restores skin hydration; it may also add volume to the lips and enhance their contour.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePosition within the range:\u003c\/b\u003e it shares its concentration with Deep Lines, Kiss and Ultra Deep (25 mg\/ml). Compared with Deep Lines, which is directed at marked folds, Global Action is positioned as a general-purpose reference.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Teosyal PureSense range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 1\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eNon-cross-linked\u003c\/b\u003e HA 15 mg\/ml + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; skin quality and hydration \u0026middot; \u0026ge; 3 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 2\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml (cross-linking \u0026lt; 10 %) + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; periorbital region and tear trough \u0026middot; \u0026ge; 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eGlobal Action \u003cb\u003e(this product)\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; wrinkles and skin depressions, lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDeep Lines\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; marked wrinkles and depressions \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eKiss\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; lips and perioral region \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltra Deep\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1.2 ml \u0026middot; 25G 1\" \u0026mdash; facial volume and contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltimate\u003c\/th\u003e\u003ctd\u003eHA 22 mg\/ml \u0026middot; 1 ml \u0026mdash; facial contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\u003cp\u003eThe cross-linked PureSense range declares a \u003cb\u003edegree of cross-linking below 10 %\u003c\/b\u003e (NMR), compared with the \u0026lt; 5 % of the RHA range. It is a firmer gel with a greater capacity for projection at an equal concentration; the RHA range instead prioritises adaptation to movement in areas of high facial animation. Redensity 1 falls outside this logic: it is not cross-linked and provides no volume.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eCorrection of wrinkles and skin depressions and restoration of skin hydration. According to the manufacturer's product information, it may also be used to add volume to the lips or to enhance their contour.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote on the documentation:\u003c\/b\u003e this reference belongs to the classic generation of the PureSense range. Teoxane does not currently publish specific instructions for use for it in its IFU repository, so this information sheet is limited to the data set out in the manufacturer's official product information. The needle gauges supplied and the injection plane do not appear in that documentation and are for that reason not stated here: consult the instructions for use supplied with the pack.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eTeoxane SA (Laboratoires Teoxane), Geneva, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 25 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 0.3 % by mass\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEstimated duration\u003c\/th\u003e\u003ctd\u003e12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eMaximum volume per session\u003c\/th\u003e\u003ctd\u003e6 ml (common limit of the Teosyal range)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 \u0026deg;C and 25 \u0026deg;C, protected from direct sunlight.\u003c\/li\u003e\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise the syringe or the needles.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 1 ml, and two traceability labels per syringe \u0026mdash; one to be given to the patient and one for the medical record.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e skin disorders, inflammation or infection in or near the treatment area; allergy to hyaluronic acid and a history of severe allergy or anaphylactic shock; allergy to lidocaine or to amide-type local anaesthetics; recent peel, laser or ultrasound treatment; autoimmune diseases; heart disease or treatment with beta-blockers; hepatocellular insufficiency or treatment for liver disease; epilepsy; porphyria; pregnancy, breastfeeding and patients under 18 years of age.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eVascular warning:\u003c\/b\u003e intravascular injection may cause vascular occlusion, ischaemia and necrosis of the treated area. In the most serious cases it may lead to visual disturbances or blindness and to cerebral ischaemia or haemorrhage. Never inject intravascularly.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBefore injection:\u003c\/b\u003e do not treat if a dental procedure has been performed in the previous 15 days; avoid aspirin, anti-inflammatory drugs, anticoagulants and vitamin E during the preceding week; avoid alcohol and intense sun exposure on the previous day and on the day itself; remove make-up completely.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e during the first 12 hours, do not apply make-up or undertake intense exertion; during the following week, avoid alcohol, prolonged sun or UV exposure, temperatures below 0 \u0026deg;C, sauna and hammam; for 15 days, do not undergo dental procedures or other aesthetic treatments.\u003c\/p\u003e\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Teoxane SA (patient product information, Rev. 01, which sets out the composition and the estimated duration of this reference). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Teoxane","offers":[{"title":"Default Title","offer_id":51007638372692,"sku":"TEO002","price":150.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/teosyal_global_action.jpg?v=1747778641"},{"product_id":"sculptra","title":"Sculptra 2x5ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSculptra is Galderma's collagen stimulator based on poly-L-lactic acid (PLLA). It is not a hyaluronic acid filler: it does not provide immediate volume, but induces the neosynthesis of collagen progressively over several sessions. It is supplied as a lyophilised powder in 2 vials of 150 mg and requires reconstitution before use.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eActive substance\u003c\/b\u003e PLLA 150 mg\/vial\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePresentation\u003c\/b\u003e 2 lyophilised vials\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReconstitution\u003c\/b\u003e 5\u0026ndash;8 ml of sterile water\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 25G\u0026ndash;26G (18G for reconstitution)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e sessions at intervals of ≥ 4 weeks\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and mechanism of action\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePoly-L-lactic acid (PLLA):\u003c\/b\u003e 150 mg per vial. A synthetic, biocompatible and resorbable polymer.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSodium carboxymethylcellulose:\u003c\/b\u003e 90 mg per vial (suspending agent).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNon-pyrogenic mannitol:\u003c\/b\u003e 127.5 mg per vial (bulking agent for lyophilisation).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism:\u003c\/b\u003e Sculptra is not a hyaluronic acid filler and does not in itself provide immediate volume. The PLLA microparticles induce a controlled tissue response that stimulates collagen neosynthesis; the result is progressive and builds up over several weeks after each session. The PLLA is resorbed; the visible effect corresponds to the newly formed collagen.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eClinical consequence:\u003c\/b\u003e the product is dosed by sessions, not by immediate correction. Overcorrecting in the first session is the most frequent error, because the effect is not yet visible at that moment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eReconstitution and preparation\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eSculptra is supplied as a lyophilised powder and must be reconstituted before use.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eDiluent:\u003c\/b\u003e 5 to 8 ml of sterile water for injection per vial.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOptional anaesthetic:\u003c\/b\u003e 1 ml of 2 % lidocaine may be added, giving a final volume of 6 to 9 ml per vial.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReconstitution needle:\u003c\/b\u003e 18G. The 18G needle is used solely to reconstitute and to draw up, never to inject.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eStanding time:\u003c\/b\u003e according to the current instructions for use, the reconstituted product may be used immediately or stored for up to 72 hours before injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eStorage of the reconstituted product:\u003c\/b\u003e up to 72 hours, refrigerated (2\u0026ndash;8 °C) or at room temperature (maximum 30 °C).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBefore drawing up:\u003c\/b\u003e shake the vial to obtain a homogeneous suspension. The homogeneity of the suspension directly determines the risk of needle blockage and of irregular deposition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eAugmentation of facial volume in depressed areas, folds and wrinkles, and correction of facial fat loss (lipoatrophy).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMalar region and midface\u003c\/li\u003e\n\u003cli\u003eTemporal region\u003c\/li\u003e\n\u003cli\u003eNasolabial sulcus and preauricular area\u003c\/li\u003e\n\u003cli\u003eJawline\u003c\/li\u003e\n\u003cli\u003eFacial lipoatrophy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eDo not inject\u003c\/b\u003e into the lips or into the periorbital region.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and session protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis, subcutaneous tissue or supraperiosteal plane, according to the area.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInjection needle:\u003c\/b\u003e 25G or 26G.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear or fanning retrograde injection, depositing in continuous movement. Avoid a static bolus and superficial placement.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eFirst session:\u003c\/b\u003e a \u003cb\u003elimited\u003c\/b\u003e correction must be performed. The result is not immediate and overcorrecting in the first session produces excess volume weeks later.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReassessment:\u003c\/b\u003e not earlier than 4 weeks after the session. Only then is it decided whether a further session is appropriate.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNumber of sessions:\u003c\/b\u003e several sessions are usually required, with a minimum interval of 4 weeks between them. The total number depends on the degree of correction achieved at each reassessment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAfter treatment:\u003c\/b\u003e massage of the treated area according to the schedule indicated by the manufacturer, in order to favour homogeneous distribution of the product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003ePoly-L-lactic acid (PLLA) 150 mg per vial\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExcipients\u003c\/th\u003e\u003ctd\u003eSodium carboxymethylcellulose 90 mg \u0026middot; mannitol 127.5 mg per vial\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 vials of lyophilised powder for reconstitution\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eReconstitution\u003c\/th\u003e\u003ctd\u003e5\u0026ndash;8 ml of sterile water for injection (optional: +1 ml of 2 % lidocaine)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e18G for reconstitution \u0026middot; 25G or 26G for injection\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDeep dermis, subcutaneous or supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003eLimited correction in the first session; reassessment not earlier than 4 weeks\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eUnopened vials:\u003c\/b\u003e store at controlled room temperature, between 15 and 30 °C, protected from heat. Do not freeze. \u003cb\u003eThey do not require refrigeration.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReconstituted product:\u003c\/b\u003e up to 72 hours, refrigerated (2\u0026ndash;8 °C) or at room temperature (maximum 30 °C).\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 single-use glass vials with 150 mg of lyophilised PLLA each and instructions for use. Sterile water for injection, lidocaine and needles are not included.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to any of the components; presence of active inflammation or infection in the area to be treated; history of severe allergies or of anaphylactic reaction.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e history of hypertrophic or keloid scarring; coagulation disorders or anticoagulant or antiplatelet therapy; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e avoid superficial placement of the product, which is associated with the formation of subcutaneous nodules and papules. Do not inject intravascularly: intravascular injection may cause vascular occlusion, skin necrosis and serious complications, including visual disturbances or stroke. Do not inject into the lips or into the periorbital region.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (instructions for use Sculptra®, Q-Med AB \/ Galderma). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51007638667604,"sku":"SCU001","price":288.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/sculptra.jpg?v=1747685455"},{"product_id":"jalupro-classic","title":"Jalupro Classic","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJALUPRO® Classic is the original product of the Amino Acid Replacement Therapy developed by Professional Derma. It is a two-component system for extemporaneous reconstitution: vials of lyophilised amino acids — glycine, L-proline, L-leucine and L-lysine — which are dissolved in low-molecular-weight sodium hyaluronate immediately before injection. Within the injectable range it is the reference for body biorevitalisation, scars and hair support.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eAmino acids\u003c\/b\u003e glycine, L-proline, L-leucine, L-lysine\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 30 mg per vial, low molecular weight\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSystem\u003c\/b\u003e two-component, 2 + 2 vials\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 30G\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRoute\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eJALUPRO® Classic is supplied as \u003cb\u003etwo separate components that are mixed at the time of use\u003c\/b\u003e:\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eAmino acid component\u003c\/th\u003e\u003ctd\u003e2 vials of lyophilised amino acids: \u003cb\u003eglycine, L-proline, L-leucine and L-lysine\u003c\/b\u003e (2 × 100 mg according to the pack designation)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHyaluronic component\u003c\/th\u003e\u003ctd\u003e2 vials each containing \u003cb\u003e30 mg of sodium hyaluronate\u003c\/b\u003e, of low molecular weight, intended to reconstitute the lyophilisate\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003ePrinciple of amino acid replacement therapy:\u003c\/b\u003e the fibroblast synthesises collagen from amino acids. Glycine and L-proline are the predominant residues of the collagen triple helix; L-lysine is involved in the cross-linking of the fibres. The manufacturer formulates the product to deliver these building blocks of synthesis directly to the tissue, while the low-molecular-weight hyaluronic acid acts as the vehicle and provides hydration.\u003c\/p\u003e\n\u003cp\u003eLyophilisation keeps the amino acids stable until the moment of application: the solution is prepared in the clinic and used immediately.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the JALUPRO® injectable range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Classic\u003c\/th\u003e\u003ctd\u003eLyophilised amino acids + \u003cb\u003elow-molecular-weight\u003c\/b\u003e sodium hyaluronate. 2 + 2 vial system with extemporaneous reconstitution. Body biorevitalisation, scars, stretch marks and hair support. Intradermal papules with a 30G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® HMW\u003c\/th\u003e\u003ctd\u003eAmino acids + \u003cb\u003ehigh-molecular-weight\u003c\/b\u003e sodium hyaluronate (20 mg). Pre-filled syringe of 1.5 ml + 1 ml vial. Face, neck, décolleté, hands and lip rejuvenation without adding volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Super Hydro\u003c\/th\u003e\u003ctd\u003eAmino acids + three biopeptides + high \u003cb\u003eand\u003c\/b\u003e low molecular weight HA in high concentration. Pre-filled syringe of 2.5 ml. Support of facial ligaments and deep connective tissue. Subdermal boluses of 0.2 ml with a 27G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Young Eye\u003c\/th\u003e\u003ctd\u003eSeven amino acids + three peptides + dual-density HA. 1.0 ml. Exclusively for the periocular area. Deep dermis, 32G needle or 30G cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll four share the same amino acid replacement principle; they differ in the molecular weight of the hyaluronic acid, the amino acid profile and the target area.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIndications according to the manufacturer:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSkin biorevitalisation, particularly of the body\u003c\/li\u003e\n\u003cli\u003eStretch marks\u003c\/li\u003e\n\u003cli\u003eScars and cutaneous depressions — the development of JALUPRO® originated in wound healing\u003c\/li\u003e\n\u003cli\u003ePhotoageing and skin ageing of the face and body\u003c\/li\u003e\n\u003cli\u003ePreparation, enhancement and prolongation of the results of other aesthetic medicine procedures\u003c\/li\u003e\n\u003cli\u003eHair support and scalp health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTreatment areas:\u003c\/b\u003e face, neck, décolleté, hands, inner thighs, abdomen, knee region and axillae. Scalp.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eReconstitution:\u003c\/b\u003e transfer the contents of the sodium hyaluronate vial into the vial containing the lyophilised amino acids. Shake gently until completely dissolved. Use immediately after mixing.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTechnique:\u003c\/b\u003e intradermal injection in superficial papules with a \u003cb\u003e30G needle\u003c\/b\u003e, spacing the papules \u003cb\u003e1.5 to 2 cm\u003c\/b\u003e apart.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAnaesthesia:\u003c\/b\u003e the manufacturer recommends applying a topical anaesthetic cream to the area before the procedure.\u003c\/p\u003e\n\u003cp\u003eFor the correction of wrinkles and depressions, linear retrograde injection may also be used, inserting the needle along the furrow and releasing the product during progressive withdrawal. If necessary, apply light massage to shape the treated area.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eProfessional Derma SA, Lugano (Switzerland)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredients\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline, L-leucine, L-lysine + low-molecular-weight sodium hyaluronate\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 vials of lyophilised amino acids + 2 vials containing 30 mg of sodium hyaluronate\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePreparation\u003c\/th\u003e\u003ctd\u003eExtemporaneous reconstitution (mixing of both components before injection)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e30G\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 vials of lyophilised amino acids\u003c\/li\u003e\n\u003cli\u003e2 vials containing 30 mg of sodium hyaluronate\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSterile single-use product. Store protected from direct light and heat sources, under the conditions stated on the packaging. Do not freeze. Do not use after the expiry date. Once reconstituted, the product must be used immediately and cannot be stored.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eDo not apply in case of known allergy to any of the components; infections, active inflammation, lesions or dermatoses in the treatment area; autoimmune disease or ongoing immunotherapy; keloid tendency. Not recommended in pregnancy and breastfeeding or in patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eProduct for medical application only, under aseptic conditions. Always consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Professional Derma SA (JALUPRO® product data sheets). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Professional Derma","offers":[{"title":"Default Title","offer_id":51007639028052,"sku":"JAL001","price":62.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/jalupro_155669de-756c-4dff-9090-9c748fa2be77.jpg?v=1747752606"},{"product_id":"jalupro-hmw","title":"Jalupro HMW 1x1.5 \u0026 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJALUPRO® HMW is the facial variant of Professional Derma's amino acid replacement therapy: it combines the same amino acid cluster as JALUPRO® Classic with \u003cb\u003ehigh molecular weight\u003c\/b\u003e sodium hyaluronate (High Molecular Weight), aimed at hydration and skin quality rather than filling. It is supplied as a two-component system — a 1.5 ml pre-filled syringe with the sodium hyaluronate gel and a 1 ml vial with the amino acid solution — which are mixed at the time of application.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eSodium hyaluronate\u003c\/b\u003e 20 mg, high molecular weight\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAmino acids\u003c\/b\u003e glycine, L-proline, L-leucine, L-lysine\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1.5 ml syringe + 1 ml vial\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRoute\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNo needles\u003c\/b\u003e included\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eSterile, resorbable injectable solution consisting of two components that are combined before use:\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePre-filled glass syringe (1.5 ml)\u003c\/th\u003e\u003ctd\u003eSterile, pyrogen-free gel of \u003cb\u003esodium hyaluronate, 20 mg\u003c\/b\u003e, of high molecular weight\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eGlass vial (1 ml)\u003c\/th\u003e\u003ctd\u003eSterile amino acid solution: \u003cb\u003eglycine, L-proline, L-leucine and L-lysine\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003eWhy high molecular weight:\u003c\/b\u003e long-chain sodium hyaluronate retains water in the dermal compartment and provides sustained hydration without generating the volumising effect typical of a cross-linked filler. This is the functional difference from JALUPRO® Classic, which is formulated with low-molecular-weight hyaluronic acid. For this reason the manufacturer also indicates JALUPRO® HMW for lip rejuvenation where tissue quality is sought without increasing volume.\u003c\/p\u003e\n\u003cp\u003eThe amino acid cluster supplies the fibroblast with the building blocks of collagen and elastin synthesis: glycine and L-proline as the predominant residues of the triple helix, L-lysine in the cross-linking of the fibres and L-leucine as an essential amino acid.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the JALUPRO® injectable range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Classic\u003c\/th\u003e\u003ctd\u003eLyophilised amino acids + \u003cb\u003elow-molecular-weight\u003c\/b\u003e sodium hyaluronate. 2 + 2 vial system with extemporaneous reconstitution. Body biorevitalisation, scars, stretch marks and hair support. Intradermal papules with a 30G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® HMW\u003c\/th\u003e\u003ctd\u003eAmino acids + \u003cb\u003ehigh-molecular-weight\u003c\/b\u003e sodium hyaluronate (20 mg). Pre-filled syringe of 1.5 ml + 1 ml vial. Face, neck, décolleté, hands and lip rejuvenation without adding volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Super Hydro\u003c\/th\u003e\u003ctd\u003eAmino acids + three biopeptides + high \u003cb\u003eand\u003c\/b\u003e low molecular weight HA in high concentration. Pre-filled syringe of 2.5 ml. Support of facial ligaments and deep connective tissue. Subdermal boluses of 0.2 ml with a 27G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Young Eye\u003c\/th\u003e\u003ctd\u003eSeven amino acids + three peptides + dual-density HA. 1.0 ml. Exclusively for the periocular area. Deep dermis, 32G needle or 30G cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll four share the same amino acid replacement principle; they differ in the molecular weight of the hyaluronic acid, the amino acid profile and the target area.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIndications according to the manufacturer:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePhotoageing and skin ageing of the face and body, of moderate and severe degree\u003c\/li\u003e\n\u003cli\u003eDry and dehydrated skin\u003c\/li\u003e\n\u003cli\u003eSkin defects and depressions caused by marked wrinkles and scars\u003c\/li\u003e\n\u003cli\u003eProcedures carried out during the summer months\u003c\/li\u003e\n\u003cli\u003eStart of the revitalisation cycle, which may be combined with JALUPRO® Classic\u003c\/li\u003e\n\u003cli\u003ePreparation, enhancement and prolongation of the results of other aesthetic procedures; adjunct in peelings and laser treatments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTreatment areas:\u003c\/b\u003e face, neck, décolleté, hands, axillae, inner thighs, abdomen and knee region. Lips, for rejuvenation without adding volume.\u003c\/p\u003e\n\u003cp\u003eThe manufacturer reports that the biorevitalising efficacy increases progressively and is maintained for six months.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003ePreparation:\u003c\/b\u003e mix the sodium hyaluronate gel from the pre-filled syringe with the amino acid solution from the vial following the procedure indicated by the manufacturer. Apply immediately after mixing.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eValidated injection techniques:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMicropapules (intradermal multi-puncture)\u003c\/li\u003e\n\u003cli\u003eLinear retrograde\u003c\/li\u003e\n\u003cli\u003eFanning\u003c\/li\u003e\n\u003cli\u003eCross-hatching (grid)\u003c\/li\u003e\n\u003cli\u003eMixed technique\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eExecution:\u003c\/b\u003e insert the needle along the wrinkle and withdraw it progressively while releasing the product. After injection, if necessary, apply light massage to shape the treated area. For the correction of fine wrinkles, the recommended injection level is the reticular dermis.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAnaesthesia:\u003c\/b\u003e local anaesthesia with 0.5–1 ml of 2 % procaine may be combined in order to reduce the stinging sensation after injection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNote:\u003c\/b\u003e the pack does not include needles; the practitioner must supply their own.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eProfessional Derma SA, Lugano (Switzerland)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredients\u003c\/th\u003e\u003ctd\u003eHigh-molecular-weight sodium hyaluronate 20 mg + glycine, L-proline, L-leucine and L-lysine\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled glass syringe of 1.5 ml + 1 glass vial of 1 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePreparation\u003c\/th\u003e\u003ctd\u003eExtemporaneous mixing of both components before injection\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal (reticular dermis for fine wrinkles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003eNot included in the pack\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e1 disposable, pyrogen-free glass syringe of 1.5 ml with sterile sodium hyaluronate gel\u003c\/li\u003e\n\u003cli\u003e1 glass vial of 1 ml with sterile amino acid solution\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSterile single-use product. Store protected from direct light and heat sources, under the conditions stated on the packaging. Do not freeze. Do not use after the expiry date. Once mixed, the product must be used immediately.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eDo not apply in case of known allergy to any of the components; infections, active inflammation, lesions or dermatoses in the treatment area; autoimmune disease or ongoing immunotherapy; keloid tendency. Not recommended in pregnancy and breastfeeding or in patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eProduct for medical application only, under aseptic conditions. Always consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Professional Derma SA (JALUPRO® product data sheets). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Professional Derma","offers":[{"title":"Default Title","offer_id":51007639290196,"sku":"JAL002","price":62.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/jalupro_hmw_6a731d5e-3ab9-4790-8c22-eb60b7f0ac0e.jpg?v=1747752722"},{"product_id":"jalupro-super-hydro","title":"Jalupro Super Hydro 1x2.5ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eJALUPRO® Super Hydro is the densest formulation in Professional Derma's injectable range. It combines the amino acid cluster characteristic of JALUPRO® with three biopeptides and a high concentration of high- and low-molecular-weight hyaluronic acid, in a 2.5 ml pre-filled syringe. It is not applied in the superficial dermis: it is injected in subdermal boluses over the projection of the main facial ligaments, with the aim of supporting the deep connective tissue and the retinaculum cutis.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 pre-filled syringe of 2.5 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e high and low molecular weight\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBiopeptides\u003c\/b\u003e 3\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBolus\u003c\/b\u003e 0.2 ml subdermal\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 27G\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eSterile, resorbable injectable solution, ready to use in a pre-filled syringe. Composition according to the manufacturer:\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eAmino acids\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline, L-leucine and L-lysine — the cluster of the JALUPRO® amino acid replacement therapy\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eBiopeptides\u003c\/th\u003e\u003ctd\u003eAcetyl decapeptide-3, oligopeptide-24 and acetyl tetrapeptide-5\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHyaluronic acid\u003c\/th\u003e\u003ctd\u003eHigh concentration, combining \u003cb\u003ehigh and low molecular weight\u003c\/b\u003e\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cb\u003eDual molecular weight:\u003c\/b\u003e the high-molecular-weight fraction provides the viscosity required for mechanical support of the subdermal compartment; the low-molecular-weight fraction diffuses and contributes to tissue hydration. This combination is what distinguishes Super Hydro within the range, together with the inclusion of biopeptides, which are absent from Classic and HMW.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAnatomical target:\u003c\/b\u003e the manufacturer positions the product over the facial retaining ligaments and the deep connective tissue — including the retinaculum cutis — not over the papillary dermis. Hence the bolus technique and the larger-gauge needle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the JALUPRO® injectable range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Classic\u003c\/th\u003e\u003ctd\u003eLyophilised amino acids + \u003cb\u003elow-molecular-weight\u003c\/b\u003e sodium hyaluronate. 2 + 2 vial system with extemporaneous reconstitution. Body biorevitalisation, scars, stretch marks and hair support. Intradermal papules with a 30G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® HMW\u003c\/th\u003e\u003ctd\u003eAmino acids + \u003cb\u003ehigh-molecular-weight\u003c\/b\u003e sodium hyaluronate (20 mg). Pre-filled syringe of 1.5 ml + 1 ml vial. Face, neck, décolleté, hands and lip rejuvenation without adding volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Super Hydro\u003c\/th\u003e\u003ctd\u003eAmino acids + three biopeptides + high \u003cb\u003eand\u003c\/b\u003e low molecular weight HA in high concentration. Pre-filled syringe of 2.5 ml. Support of facial ligaments and deep connective tissue. Subdermal boluses of 0.2 ml with a 27G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eJALUPRO® Young Eye\u003c\/th\u003e\u003ctd\u003eSeven amino acids + three peptides + dual-density HA. 1.0 ml. Exclusively for the periocular area. Deep dermis, 32G needle or 30G cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll four share the same amino acid replacement principle; they differ in the molecular weight of the hyaluronic acid, the amino acid profile and the target area.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIndications according to the manufacturer:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePhotoageing and skin ageing of the face and body, of moderate and severe degree\u003c\/li\u003e\n\u003cli\u003eDry and dehydrated skin\u003c\/li\u003e\n\u003cli\u003eSkin laxity and loss of structural support of the middle and lower facial thirds\u003c\/li\u003e\n\u003cli\u003eSupport and regeneration of the deep connective tissue and the facial retaining ligaments\u003c\/li\u003e\n\u003cli\u003eDeep biorevitalisation of the extracellular matrix\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTreatment areas:\u003c\/b\u003e face (points of the main facial ligaments). The manufacturer also envisages the neck, décolleté, hands, inner thighs, knee region and axillae.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e injection of \u003cb\u003e0.2 ml boluses\u003c\/b\u003e in the subdermal plane, over the location of the main facial ligaments.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 27G.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e one session per month, a minimum of 4 sessions, adjusting the number according to the patient's presentation and medical judgement.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePresentation:\u003c\/b\u003e pre-filled syringe ready to use, with no prior mixing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs this is a deep application over defined anatomical points, it requires precise knowledge of the anatomy of the facial retaining ligaments and of the vascularisation of the area.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eProfessional Derma SA, Lugano (Switzerland)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredients\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline, L-leucine and L-lysine; acetyl decapeptide-3, oligopeptide-24, acetyl tetrapeptide-5; high- and low-molecular-weight hyaluronic acid\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.5 ml, sterile and ready to use\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — subdermal, in 0.2 ml boluses\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e27G\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003eMonthly, minimum 4 sessions\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2.5 ml of JALUPRO® Super Hydro.\u003c\/p\u003e\n\u003cp\u003eSterile single-use product. Store protected from direct light and heat sources, under the conditions stated on the packaging. Do not freeze. Do not use after the expiry date.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eDo not apply in case of known allergy to any of the components; infections, active inflammation, lesions or dermatoses in the treatment area; autoimmune disease or ongoing immunotherapy; keloid tendency. Not recommended in pregnancy and breastfeeding or in patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eProduct for medical application only, under aseptic conditions and by professionals trained in deep facial anatomy. Always consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Professional Derma SA (JALUPRO® product data sheets). This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Professional Derma","offers":[{"title":"Default Title","offer_id":51007639519572,"sku":"JAL003","price":75.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/jalupro_superhydro.jpg?v=1747756332"},{"product_id":"saypha-filler","title":"Croma Saypha Filler Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSaypha® Filler with lidocaine is the cross-linked hyaluronic acid filler from Croma-Pharma indicated for the correction of moderate nasolabial folds. With 23 mg\/ml of HA and a degree of cross-linking of 0.5–1.0 %, it is the least firm gel of the injectable Saypha range: it is designed to work in the mid to deep dermis, not to provide structural volume.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 23 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e 0.5–1.0 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\"\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 23 mg\/ml, of non-animal origin obtained by bacterial fermentation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e 0.5–1.0 %. This is the lowest value in the cross-linked Saypha range and defines the positioning of the product: a soft gel, easy to mould, for the correction of lines and not for projection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine:\u003c\/b\u003e 0.3 % (3 mg\/ml), incorporated into the gel to reduce discomfort during injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturing:\u003c\/b\u003e in-house production by Croma-Pharma in Leobendorf (Austria), with a pre-filled syringe sterilised by moist heat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Saypha variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Filler (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — moderate nasolabial folds, mid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.5 % — severe nasolabial folds, deep dermis and subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume Plus lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml, cross-linking 1.0–2.0 % — volume deficit of the midface, deep subcutaneous or supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Lips lidocaine\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — lip augmentation, submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Rich\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 18 mg\/ml + glycerol — skin revitalisation in the superficial dermis. It is not a volumising filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid implant indicated by the manufacturer for the correction of \u003cb\u003emoderate nasolabial folds\u003c\/b\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eModerate nasolabial folds\u003c\/li\u003e\n\u003cli\u003ePerioral lines and lines of the lower third of moderate intensity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor severe wrinkles or for volumetric restoration of the midface, the range provides Saypha Volume and Saypha Volume Plus respectively.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 × 27G ½\" thin wall Terumo™, which reduce the extrusion force required.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde, fanning or cross-hatching, according to the morphology of the fold.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e in the clinical study of the Saypha range in nasolabial folds the correction was maintained for up to 9 months.\u003c\/li\u003e\n\u003cli\u003eInject slowly and retrograde. Do not inject intravascularly. Do not apply over areas with permanent implants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Leobendorf, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 23 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e0.5–1.0 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine 0.3 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\" thin wall Terumo™\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device, CE mark 0123 (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 27G ½\", instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins; allergy to lidocaine or to amide-type local anaesthetics; porphyria; active autoimmune disease; tendency to hypertrophic or keloid scarring; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e anticoagulant or antiplatelet therapy; history of severe allergic reactions; areas previously treated with permanent implants. Do not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma (Saypha portfolio brochure). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51007641813332,"sku":"SAY001","price":58.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/saypha_filler_lidocaina.jpg?v=1745240230"},{"product_id":"saypha-volume-lidocaina","title":"Croma Saypha Volume Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSaypha® Volume with lidocaine is the cross-linked hyaluronic acid filler from Croma-Pharma indicated for the correction of severe nasolabial folds. It retains the 23 mg\/ml of HA of Saypha Filler but raises the degree of cross-linking to 0.5–1.5 %, which gives it a firmer gel suitable for working in the deep dermis and subcutis.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 23 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e 0.5–1.5 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\"\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 23 mg\/ml, of non-animal origin obtained by bacterial fermentation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e 0.5–1.5 %. This is the functional difference compared with Saypha Filler: at the same HA concentration, the higher cross-linking density increases the gel's resistance to deformation and prolongs its persistence in deep planes.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine:\u003c\/b\u003e 0.3 % (3 mg\/ml), incorporated into the gel to reduce discomfort during injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturing:\u003c\/b\u003e in-house production by Croma-Pharma in Leobendorf (Austria), pre-filled syringe sterilised by moist heat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Saypha variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Filler (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — moderate nasolabial folds, mid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.5 % — severe nasolabial folds, deep dermis and subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume Plus lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml, cross-linking 1.0–2.0 % — volume deficit of the midface, deep subcutaneous or supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Lips lidocaine\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — lip augmentation, submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Rich\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 18 mg\/ml + glycerol — skin revitalisation in the superficial dermis. It is not a volumising filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid implant indicated by the manufacturer for the correction of \u003cb\u003esevere nasolabial folds\u003c\/b\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSevere nasolabial folds\u003c\/li\u003e\n\u003cli\u003eDeep folds of the lower facial third\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor volume deficit of the midface, the range provides Saypha Volume Plus, with a higher concentration and degree of cross-linking.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis and subcutaneous tissue.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 × 27G ½\" thin wall Terumo™.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde or fanning, with slow injection and prior aspiration according to clinical protocol.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e in the clinical study of the Saypha range in nasolabial folds the correction was maintained for up to 9 months.\u003c\/li\u003e\n\u003cli\u003eNever inject intravascularly. Do not apply over areas with permanent implants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Leobendorf, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 23 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e0.5–1.5 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine 0.3 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\" thin wall Terumo™\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDeep dermis, subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device, CE mark 0123 (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 27G ½\", instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins; allergy to lidocaine or to amide-type local anaesthetics; porphyria; active autoimmune disease; tendency to hypertrophic or keloid scarring; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e anticoagulant or antiplatelet therapy; history of severe allergic reactions; areas with permanent implants. Do not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma (Saypha portfolio brochure). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51007642042708,"sku":"SAY005","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/saypha_volume_lidocaina.jpg?v=1745239918"},{"product_id":"saypha-rich","title":"Croma Saypha Rich 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSaypha® Rich is the skinbooster of the Croma-Pharma range: \u003cb\u003enon-cross-linked\u003c\/b\u003e hyaluronic acid at 18 mg\/ml combined with glycerol. Unlike the rest of the Saypha range, it is not a filler and provides neither volume nor projection; it is injected into the superficial dermis to improve hydration, tone and elasticity. It replaces the former Princess Rich reference.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 18 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycerol\u003c\/b\u003e yes\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAnaesthetic\u003c\/b\u003e without lidocaine\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e superficial dermis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 18 mg\/ml, of non-animal origin obtained by bacterial fermentation. As it is not cross-linked, the gel is fluid, distributes within the tissue and is completely resorbed; it does not create structural support.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycerol:\u003c\/b\u003e a humectant that retains water in the dermis and, in non-cross-linked HA formulations, additionally helps to stabilise the gel against degradation by free radicals.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout lidocaine\u003c\/b\u003e and without cross-linking agent (BDDE).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eFunctional difference:\u003c\/b\u003e Saypha Filler, Volume, Volume Plus and Lips are cross-linked gels that occupy volume; Saypha Rich acts on skin quality. They are distinct and complementary categories, not alternatives.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Saypha variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Filler (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — moderate nasolabial folds, mid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.5 % — severe nasolabial folds, deep dermis and subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume Plus lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml, cross-linking 1.0–2.0 % — volume deficit of the midface, deep subcutaneous or supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Lips lidocaine\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — lip augmentation, submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Rich\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 18 mg\/ml + glycerol — skin revitalisation in the superficial dermis. It is not a volumising filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eProduct intended for skin revitalisation and hydro-biostimulation treatments: improvement of skin hydration, tone and elasticity.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace, in particular the cheekbones, midface and perioral area\u003c\/li\u003e\n\u003cli\u003eNeck and décolleté\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is not indicated for correcting deep folds or for restoring volume: for those indications the range provides Saypha Filler, Volume or Volume Plus.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e superficial dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e mesotherapy — micropapules, multiple puncture or linear retrograde, with a fine needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e the treatment is usually planned as a series of several sessions spaced a few weeks apart, followed by maintenance sessions. The binding number of sessions and interval are those set out in the instructions for use of the product.\u003c\/li\u003e\n\u003cli\u003eCompatible with combined protocols alongside cross-linked fillers in separate sessions.\u003c\/li\u003e\n\u003cli\u003eResorbable product: the effect is transient and requires maintenance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Leobendorf, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid 18 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive excipient\u003c\/th\u003e\u003ctd\u003eGlycerol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eSuperficial dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCategory\u003c\/th\u003e\u003ctd\u003eSkinbooster \/ injectable revitaliser. It is not a volumising dermal filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, sterile needles, instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid, to glycerol or to Gram-positive bacterial proteins; active autoimmune disease; tendency to hypertrophic or keloid scarring; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e anticoagulant or antiplatelet therapy; areas with permanent implants. Do not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on documentation from the manufacturer Croma-Pharma. This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51007642272084,"sku":"SAY002","price":34.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/saypha_rich.jpg?v=1745239621"},{"product_id":"neauvia-intense-1x1ml","title":"Neauvia Intense 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eNeauvia Organic Intense is the highest-concentration filler in the MATEX LAB range: a hyaluronic acid hydrogel at 28 mg\/ml cross-linked with PEGDE, not with BDDE. It is intended for volumetric restoration of facial soft tissue by injection into the subcutaneous or supraperiosteal plane, with a high extrusion force and a 21G\/22G needle guide included in the pack.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 28 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker\u003c\/b\u003e PEGDE\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\/cannula\u003c\/b\u003e 21G\/22G included\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 6 months (mean degradation)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 28 mg\/ml, the highest concentration in the Neauvia range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e PEGDE (polyethylene glycol diglycidyl ether).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycine and L-proline\u003c\/b\u003e in phosphate buffer solution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNo anaesthetic:\u003c\/b\u003e the formulation does not contain lidocaine.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e high extrusion force. In the rheological characterisation published by Zerbinati et al. (\u003ci\u003ePolymers\u003c\/i\u003e 2021;13:948), the 28 mg\/ml sample of this platform showed an elastic modulus G′ of 172.83 ± 3.02 Pa at 25 °C. The study identifies the samples by concentration and not by trade name.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eCross-linking with PEGDE.\u003c\/b\u003e Neauvia uses polyethylene glycol diglycidyl ether (PEGDE) as its cross-linking agent, instead of the BDDE used by most HA fillers on the market. The manufacturer calls this platform \u003ci\u003eSmart Crosslinking Technology\u003c\/i\u003e and bases the safety profile of the range on it: no pathological inflammatory reactions detected, no cytotoxic activity, no cross-linker residues after complete degradation of the implant, and reversibility of the filler with hyaluronidase.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObjective reading of the data.\u003c\/b\u003e PEG is a well-established polymer in pharmaceutical use, and the available publications on the PEG-HA hydrogels from Matex Lab (Zerbinati et al.) describe in vitro biocompatibility and a degree of cross-linking between 2.8 % and 6.2 %. The exact PEGDE concentration is protected by patent and is not published by the manufacturer. To date there is no direct comparative trial of PEGDE versus BDDE with a primary clinical endpoint, so the advantage should be understood as a difference in cross-linking chemistry supported by physicochemical and in vitro data, not as a demonstrated clinical superiority.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGlycine and L-proline.\u003c\/b\u003e Both proteinogenic amino acids are added to the phosphate buffer solution to adjust the viscoelastic properties of the gel and its swelling resistance, with the aim of controlling the water uptake of the hydrogel in the phase following implantation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Neauvia Organic range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProduct\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA\u003c\/b\u003e · cross-linking · extrusion force · plane · area\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydro Deluxe \/ Hydro Deluxe Man\u003c\/th\u003e\u003ctd\u003e18 mg\/ml · non-cross-linked (linear) + CaHA · low · epidermis and dermis · face and neck\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rheology\u003c\/th\u003e\u003ctd\u003e22 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Lips\u003c\/th\u003e\u003ctd\u003e24 mg\/ml · PEG · medium · vermilion and\/or perioral area · lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Flux\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense LV\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium\/high · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eStimulate \/ Stimulate Man\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG \u003cb\u003e+ calcium hydroxyapatite\u003c\/b\u003e · medium\/high · subdermis and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense \/ Intense Man\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · subcutaneous and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rose\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · intradermal · labia majora (gynaecological indication)\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe entire range shares the same formulation backbone: hyaluronic acid of biotechnological origin cross-linked with PEGDE (polyethylene glycol diglycidyl ether), buffered in phosphate solution and enriched with glycine and L-proline. The difference between references lies in the HA concentration, the resulting rheology and the intended injection plane, not in the cross-linking chemistry. Hydro Deluxe is the only non-cross-linked reference; Stimulate is the only one that incorporates calcium hydroxyapatite in the gel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBiodegradable hyaluronic acid hydrogel indicated to restore lost volume of the soft tissue of the face.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMalar region and cheekbones\u003c\/li\u003e\n\u003cli\u003eProjection of the mid third of the face\u003c\/li\u003e\n\u003cli\u003eChin and jawline\u003c\/li\u003e\n\u003cli\u003eDeep folds and depressions requiring structural support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is the reference in the range with the greatest projection capacity; for superficial dermal corrections or highly mobile areas the manufacturer positions Intense Rheology or Intense Flux.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e subcutaneous and\/or supraperiosteal.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eArea:\u003c\/b\u003e face.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\/cannula guide:\u003c\/b\u003e 21G\/22G, included in the pack.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e 6 months mean degradation time according to manufacturer data.\u003c\/li\u003e\n\u003cli\u003ePrior aspiration and retrograde injection in accordance with standard clinical protocol to minimise vascular risk.\u003c\/li\u003e\n\u003cli\u003eThe manufacturer integrates the product into its synergistic mid-face protocol, combining it with lower-density references from the same range.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMATEX LAB S.p.A. — via Carlo Urbani 2 ang. via Enrico Fermi, Brindisi (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 28 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003ePEGDE (polyethylene glycol)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOther components\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline; phosphate buffer solution\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\/cannula\u003c\/th\u003e\u003ctd\u003e21G\/22G guide included\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExtrusion force\u003c\/th\u003e\u003ctd\u003eHigh\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eSubcutaneous and\/or supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDuration\u003c\/th\u003e\u003ctd\u003e6 months mean degradation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device with CE marking (EU Regulation 2017\/745, MDR)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only, trained in hyaluronic acid filler injection techniques\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 21G\/22G needle\/cannula guide, package leaflet and traceability labels.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSterile pre-filled syringe, ready for use.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003eStore under the conditions indicated on the pack, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eThe traceability labels supplied must be attached to the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe manufacturer restricts use to physicians acting in accordance with local legislation and trained in hyaluronic acid filler injection techniques.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMust not be applied in the case of:\u003c\/b\u003e known hypersensitivity to any of the components of the product; active skin infection, inflammation or lesion in the treatment area; pregnancy and breastfeeding; patients under the age of majority.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIndividual assessment:\u003c\/b\u003e autoimmune disease or immunosuppressive therapy; tendency to hypertrophic or keloid scarring; anticoagulant or antiplatelet therapy; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003eDo not inject intravascularly. Sterile single-use product: do not reuse or re-sterilise; discard the syringe and the needle after the procedure.\u003c\/p\u003e\n\u003cp\u003eThe full contraindications, warnings and possible adverse effects are listed in the package leaflet accompanying the pack and must be consulted before each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of MATEX LAB S.p.A. (Neauvia product data sheets and the manufacturer's technical pages) and on peer-reviewed literature on PEG cross-linked hyaluronic acid hydrogels. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"MatexLab","offers":[{"title":"Default Title","offer_id":51007642468692,"sku":"NEA003","price":74.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/neauvia_intense.jpg?v=1752167474"},{"product_id":"neauvia-intense","title":"Neauvia Intense LV 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eNeauvia Organic Intense LV is the variant of the Intense line with 26 mg\/ml of hyaluronic acid cross-linked with PEGDE. Compared with Intense (28 mg\/ml, subcutaneous or supraperiosteal plane), LV drops one step in density and extends the working plane to the intradermal level, with a medium\/high extrusion force that places it between a structural filler and a dermal correction filler.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 26 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker\u003c\/b\u003e PEGDE\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\/cannula\u003c\/b\u003e 21G\/22G included\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 6 months (mean degradation)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 26 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e PEGDE (polyethylene glycol diglycidyl ether).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycine and L-proline\u003c\/b\u003e in phosphate buffer solution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNo anaesthetic:\u003c\/b\u003e the formulation does not contain lidocaine.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e medium\/high extrusion force.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eCross-linking with PEGDE.\u003c\/b\u003e Neauvia uses polyethylene glycol diglycidyl ether (PEGDE) as its cross-linking agent, instead of the BDDE used by most HA fillers on the market. The manufacturer calls this platform \u003ci\u003eSmart Crosslinking Technology\u003c\/i\u003e and bases the safety profile of the range on it: no pathological inflammatory reactions detected, no cytotoxic activity, no cross-linker residues after complete degradation of the implant, and reversibility of the filler with hyaluronidase.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eObjective reading of the data.\u003c\/b\u003e PEG is a well-established polymer in pharmaceutical use, and the available publications on the PEG-HA hydrogels from Matex Lab (Zerbinati et al.) describe in vitro biocompatibility and a degree of cross-linking between 2.8 % and 6.2 %. The exact PEGDE concentration is protected by patent and is not published by the manufacturer. To date there is no direct comparative trial of PEGDE versus BDDE with a primary clinical endpoint, so the advantage should be understood as a difference in cross-linking chemistry supported by physicochemical and in vitro data, not as a demonstrated clinical superiority.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGlycine and L-proline.\u003c\/b\u003e Both proteinogenic amino acids are added to the phosphate buffer solution to adjust the viscoelastic properties of the gel and its swelling resistance, with the aim of controlling the water uptake of the hydrogel in the phase following implantation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Neauvia Organic range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProduct\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA\u003c\/b\u003e · cross-linking · extrusion force · plane · area\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydro Deluxe \/ Hydro Deluxe Man\u003c\/th\u003e\u003ctd\u003e18 mg\/ml · non-cross-linked (linear) + CaHA · low · epidermis and dermis · face and neck\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rheology\u003c\/th\u003e\u003ctd\u003e22 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Lips\u003c\/th\u003e\u003ctd\u003e24 mg\/ml · PEG · medium · vermilion and\/or perioral area · lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Flux\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense LV\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium\/high · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eStimulate \/ Stimulate Man\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG \u003cb\u003e+ calcium hydroxyapatite\u003c\/b\u003e · medium\/high · subdermis and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense \/ Intense Man\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · subcutaneous and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rose\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · intradermal · labia majora (gynaecological indication)\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe entire range shares the same formulation backbone: hyaluronic acid of biotechnological origin cross-linked with PEGDE (polyethylene glycol diglycidyl ether), buffered in phosphate solution and enriched with glycine and L-proline. The difference between references lies in the HA concentration, the resulting rheology and the intended injection plane, not in the cross-linking chemistry. Hydro Deluxe is the only non-cross-linked reference; Stimulate is the only one that incorporates calcium hydroxyapatite in the gel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBiodegradable hyaluronic acid hydrogel indicated to restore lost volume of the soft tissue of the face.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVolumetric restoration of the mid third of the face\u003c\/li\u003e\n\u003cli\u003eNasolabial folds and marionette lines\u003c\/li\u003e\n\u003cli\u003eDefinition of the facial contour\u003c\/li\u003e\n\u003cli\u003eCorrections requiring support without the maximum projection of Intense\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal and\/or subcutaneous.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eArea:\u003c\/b\u003e face.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\/cannula guide:\u003c\/b\u003e 21G\/22G, included in the pack.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e 6 months mean degradation time according to manufacturer data.\u003c\/li\u003e\n\u003cli\u003ePrior aspiration and retrograde injection in accordance with standard clinical protocol.\u003c\/li\u003e\n\u003cli\u003eIntegrated by the manufacturer into the synergistic mid-face protocol together with other references in the range.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMATEX LAB S.p.A. — via Carlo Urbani 2 ang. via Enrico Fermi, Brindisi (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 26 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003ePEGDE (polyethylene glycol)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOther components\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline; phosphate buffer solution\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\/cannula\u003c\/th\u003e\u003ctd\u003e21G\/22G guide included\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExtrusion force\u003c\/th\u003e\u003ctd\u003eMedium\/high\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eIntradermal and\/or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDuration\u003c\/th\u003e\u003ctd\u003e6 months mean degradation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device with CE marking (EU Regulation 2017\/745, MDR)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only, trained in hyaluronic acid filler injection techniques\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 21G\/22G needle\/cannula guide, package leaflet and traceability labels.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSterile pre-filled syringe, ready for use.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003eStore under the conditions indicated on the pack, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eThe traceability labels supplied must be attached to the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe manufacturer restricts use to physicians acting in accordance with local legislation and trained in hyaluronic acid filler injection techniques.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMust not be applied in the case of:\u003c\/b\u003e known hypersensitivity to any of the components of the product; active skin infection, inflammation or lesion in the treatment area; pregnancy and breastfeeding; patients under the age of majority.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIndividual assessment:\u003c\/b\u003e autoimmune disease or immunosuppressive therapy; tendency to hypertrophic or keloid scarring; anticoagulant or antiplatelet therapy; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003eDo not inject intravascularly. Sterile single-use product: do not reuse or re-sterilise; discard the syringe and the needle after the procedure.\u003c\/p\u003e\n\u003cp\u003eThe full contraindications, warnings and possible adverse effects are listed in the package leaflet accompanying the pack and must be consulted before each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of MATEX LAB S.p.A. (Neauvia product data sheets and the manufacturer's technical pages) and on peer-reviewed literature on PEG cross-linked hyaluronic acid hydrogels. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"MatexLab","offers":[{"title":"Default Title","offer_id":51007642566996,"sku":"NEA006","price":72.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/neauvia_intense_lv.jpg?v=1752167473"},{"product_id":"teosyal-ultra-deep","title":"Teosyal PureSense Ultra Deep 2x1.2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eTeosyal\u0026reg; PureSense Ultra Deep is the densest volumiser of the PureSense range: 25 mg\/ml of hyaluronic acid with cross-linking below 10 %, in \u003cb\u003e1.2 ml\u003c\/b\u003e syringes and with \u003cb\u003e25G 1\"\u003c\/b\u003e needles, the widest gauge and the greatest length in the whole Teosyal range. It is intended for the subcutaneous and supraperiosteal plane for volume restoration and contour remodelling.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eHA\u003c\/b\u003e 25 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e \u0026lt; 10 % (NMR)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 % (3 mg\/ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 1.2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 \u0026times; 25G 1\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration\u003c\/b\u003e 15\u0026ndash;18 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 25 mg\/ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e \u0026lt; 10 %, measured by nuclear magnetic resonance.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 0.3 % by mass (3 mg\/ml).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eResidual BDDE:\u003c\/b\u003e \u0026lt; 1 ppm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePhosphate buffer\u003c\/b\u003e pH 7.3 q.s. for 1.2 ml.\u003c\/li\u003e\u003cli\u003e\u003cb\u003ePerformance declared by the manufacturer:\u003c\/b\u003e it creates a volume that corrects wrinkles or facial contours and restores skin hydration.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eReading the gauge:\u003c\/b\u003e the 25G 1\" needle supplied indicates a high-density gel intended for deep planes; the superficial references of the range are supplied with 30G \u0026frac12;\".\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Teosyal PureSense range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 1\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eNon-cross-linked\u003c\/b\u003e HA 15 mg\/ml + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; skin quality and hydration \u0026middot; \u0026ge; 3 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRedensity 2\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml (cross-linking \u0026lt; 10 %) + dermo-restructuring complex \u0026middot; 1 ml \u0026middot; 30G \u0026frac12;\" \u0026mdash; periorbital region and tear trough \u0026middot; \u0026ge; 12 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eGlobal Action\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; wrinkles and skin depressions, lips \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDeep Lines\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml \u0026middot; 1 ml \u0026mdash; marked wrinkles and depressions \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eKiss\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1 ml \u0026middot; 27G \u0026frac12;\" \u0026mdash; lips and perioral region \u0026middot; 12\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltra Deep \u003cb\u003e(this product)\u003c\/b\u003e\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml (cross-linking \u0026lt; 10 %) \u0026middot; 1.2 ml \u0026middot; 25G 1\" \u0026mdash; facial volume and contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUltimate\u003c\/th\u003e\u003ctd\u003eHA 22 mg\/ml \u0026middot; 1 ml \u0026mdash; facial contour \u0026middot; 15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\u003cp\u003eThe cross-linked PureSense range declares a \u003cb\u003edegree of cross-linking below 10 %\u003c\/b\u003e (NMR), compared with the \u0026lt; 5 % of the RHA range. It is a firmer gel with a greater capacity for projection at an equal concentration; the RHA range instead prioritises adaptation to movement in areas of high facial animation. Redensity 1 falls outside this logic: it is not cross-linked and provides no volume.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eTherapeutic indication:\u003c\/b\u003e reconstructive surgery, filling of scar depressions and reconstruction of volumes lost through lipoatrophy in patients under treatment for HIV.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAesthetic indication:\u003c\/b\u003e correction of deep wrinkles and folds in areas of thick skin, remodelling of the facial contour, restoration and augmentation of volume and correction of mild tissue ptosis.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e subcutaneous or supraperiosteal.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 25G 1\", two per syringe (4 per pack).\u003c\/li\u003e\u003cli\u003e\u003cb\u003eCannula:\u003c\/b\u003e a valid alternative is a 25G blunt cannula; compatibility verified by the manufacturer with TSK 25G\/50 mm.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eMaximum volume:\u003c\/b\u003e 6 ml per session.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eEstimated duration:\u003c\/b\u003e between 15 and 18 months.\u003c\/li\u003e\u003cli\u003eDo not inject into the epidermis. Do not combine in the same session with peeling, laser or ultrasound.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eTeoxane SA (Laboratoires Teoxane), Geneva, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 25 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e\u0026lt; 10 % (NMR)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine HCl 0.3 % by mass\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE, residual \u0026lt; 1 ppm\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.3 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 1.2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 \u0026times; 25G 1\" (2 per syringe)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCompatible cannula\u003c\/th\u003e\u003ctd\u003e25G (TSK 25G\/50 mm verified)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eSubcutaneous or supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEstimated duration\u003c\/th\u003e\u003ctd\u003e15\u0026ndash;18 months\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 \u0026deg;C and 25 \u0026deg;C, protected from direct sunlight.\u003c\/li\u003e\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise the syringe or the needles.\u003c\/li\u003e\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 1.2 ml, 4 sterile 25G 1\" needles, and two traceability labels per syringe \u0026mdash; one to be given to the patient and one for the medical record.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e skin disorders, inflammation or infection in or near the treatment area; allergy to hyaluronic acid and a history of severe allergy or anaphylactic shock; allergy to lidocaine or to amide-type local anaesthetics; recent peel, laser or ultrasound treatment; autoimmune diseases; heart disease or treatment with beta-blockers; hepatocellular insufficiency or treatment for liver disease; epilepsy; porphyria; pregnancy, breastfeeding and patients under 18 years of age.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eVascular warning:\u003c\/b\u003e intravascular injection may cause vascular occlusion, ischaemia and necrosis of the treated area. In the most serious cases it may lead to visual disturbances or blindness and to cerebral ischaemia or haemorrhage. Never inject intravascularly.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBefore injection:\u003c\/b\u003e do not treat if a dental procedure has been performed in the previous 15 days; avoid aspirin, anti-inflammatory drugs, anticoagulants and vitamin E during the preceding week; avoid alcohol and intense sun exposure on the previous day and on the day itself; remove make-up completely.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e during the first 12 hours, do not apply make-up or undertake intense exertion; during the following week, avoid alcohol, prolonged sun or UV exposure, temperatures below 0 \u0026deg;C, sauna and hammam; for 15 days, do not undergo dental procedures or other aesthetic treatments.\u003c\/p\u003e\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Teoxane SA (instructions for use TEOSYAL\u0026reg; PureSense ULTRA DEEP, ref. 230592-00, and patient product information). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Teoxane","offers":[{"title":"Default Title","offer_id":51060726563156,"sku":"TEO007","price":154.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/teosyal_ultra_deep_82ee6730-58d4-4fbb-82a7-595568af140d.jpg?v=1747749542"},{"product_id":"stylage-s-bi-soft","title":"Stylage S 2x0.8ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSTYLAGE\u0026reg; S is the anaesthetic-free version of the lowest-concentration filler of the Laboratoires VIVACY range: 16 mg of hyaluronic acid cross-linked with BDDE per gram of gel, with mannitol as an antioxidant. It is injected into the superficial to mid dermis to fill skin depressions of the face and into the labial mucosa for lip contouring. Indicated when anaesthesia is preferably managed independently of the implant.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 16 mg\/g (BDDE)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAnaesthetic\u003c\/b\u003e Without lidocaine\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes \u0026times; 0.8 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 4 sterile single-use\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e Superficial to mid dermis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid (BDDE):\u003c\/b\u003e 16 mg.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePhosphate buffer and mannitol,\u003c\/b\u003e pH 7.2, q.s. for 1 g of gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout anaesthetic:\u003c\/b\u003e unlike STYLAGE\u0026reg; S Lidocaine, this reference does not contain lidocaine hydrochloride. It allows topical or nerve-block anaesthesia to be applied at the practitioner's discretion and avoids the contraindications specific to amide-type anaesthetics and to porphyria.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMannitol (antioxidant):\u003c\/b\u003e incorporated into the formulation as an antioxidant agent. According to VIVACY's technical documentation, it protects the hyaluronic acid gel against the damage caused by the free radicals (oxidative stress) generated during the injection process, thereby slowing the degradation of the hyaluronic acid. It is the distinguishing element of the STYLAGE range compared with conventional HA fillers.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eIPN-Like technology (InterPenetrated Networks):\u003c\/b\u003e VIVACY's patented cross-linking technology. It preserves the partial independence of the interpenetrated hyaluronic acid networks while increasing the density of chemical nodes. The manufacturer associates it with the optimisation of the gel's rheology —in particular the viscosity, to ensure injectability— and with the cohesivity and monophasic character of the gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linker:\u003c\/b\u003e BDDE. Hyaluronic acid of non-animal origin.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBi-SOFT\u0026reg; syringe:\u003c\/b\u003e patented bi-material injection system (polycarbonate and thermoplastic elastomer with a soft-touch surface), with oversized plunger and finger flanges and an optimised centre of gravity. It is a property of the syringe, not of the gel: it aims to reduce the perceived injection force and to improve control of the deposit.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSterile, apyrogenic gel,\u003c\/b\u003e of physiological pH and osmolarity, packaged in a pre-filled syringe and sterilised by autoclave (moist heat). The needles are sterilised by irradiation or ethylene oxide.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the variants of the STYLAGE\u0026reg; range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe range is graded by hyaluronic acid concentration and degree of cross-linking, which determines\nthe consistency of the gel and, with it, the injection plane and the indication. The concentrations\nare taken from the manufacturer's instructions for use and are expressed per gram of gel (q.s. 1 g).\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eS\u0026nbsp;\u0026mdash; 16 mg\/g\u003c\/th\u003e\u003ctd\u003eSuperficial to mid dermis. Skin depressions of the face; lip contouring by injection into the mucosa. 0.8 ml syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eM\u0026nbsp;\u0026mdash; 20 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Skin depressions; lip contouring and\/or volume augmentation; volume restoration of the dorsum of the hand by the subcutaneous route\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eL\u0026nbsp;\u0026mdash; 24 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis. Skin depressions of the face. Not indicated for superficial wrinkles, thin skin, lips or areas with an exposed vascular network\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXL\u0026nbsp;\u0026mdash; 26 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. Restoration or augmentation of facial volumes. It is the highest concentration in the range\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eXXL\u0026nbsp;\u0026mdash; 21 mg\/g\u003c\/th\u003e\u003ctd\u003eDeep dermis or subcutaneous plane. High-viscosity volumising; the only product in the range whose pack includes a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSpecial Lips\u0026nbsp;\u0026mdash; 18.5 mg\/g\u003c\/th\u003e\u003ctd\u003eLabial mucosa. Redefinition and\/or augmentation of lip volume\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydroMax\u0026nbsp;\u0026mdash; 12.5 mg\/g\u003c\/th\u003e\u003ctd\u003eMid to deep dermis. Skin hydration and elasticity. The only product in the range formulated with sorbitol instead of mannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe concentration of XXL is lower than that of XL: the range is not a linear ascending scale. XL and XXL\nshare their volumising indication and injection plane, and differ in the rheological behaviour\nof the gel \u0026mdash; the manufacturer positions XXL as a high-viscosity volumiser.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid gel intended to fill skin depressions of the face by injection into the dermis. STYLAGE\u0026reg; S is equally indicated for lip contouring (\u003ci\u003eourlement\u003c\/i\u003e) by injection into the labial mucosa.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eOutside the indication:\u003c\/b\u003e the instructions for use do not cover treatment of the tear trough or of the periorbital region, nor the restoration of facial volumes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e superficial to mid dermis of the face; labial mucosa for contouring.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended techniques:\u003c\/b\u003e linear retrograde injection, multiple-puncture technique or a combination of both.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAnaesthesia:\u003c\/b\u003e as it does not incorporate lidocaine, consider topical anaesthesia or a prior block, especially in the labial mucosa.\u003c\/li\u003e\n\u003cli\u003eOnly the needles supplied with the product should be used: the combination of both devices has been validated by the manufacturer. Screw the needle firmly onto the Luer-Lock cone.\u003c\/li\u003e\n\u003cli\u003eThe use of sterile, CE-marked blunt-tipped cannulas is possible. In that case the practitioner must select the appropriate gauge and length and scrupulously observe aseptic conditions, in particular the pre-hole.\u003c\/li\u003e\n\u003cli\u003eInject slowly to avoid overcorrection. If the injection is too deep the efficacy of the correction is reduced; if it is too superficial, skin discolouration, small indurations or an irregular correction may appear.\u003c\/li\u003e\n\u003cli\u003eIt is recommended not to inject more than 20 ml of cross-linked hyaluronic acid per person per year (all ranges combined).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSessions:\u003c\/b\u003e depending on the characteristics of the area, of the patient and of the injection depth, one or two sessions are required for an optimal treatment. Regular touch-up sessions allow the correction to be maintained.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAfter injection:\u003c\/b\u003e do not apply cold and massage the treated area thoroughly to optimise the uniformity of the correction.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eLaboratoires VIVACY, Archamps Technopole, 74160 Archamps (France)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 16 mg\/g\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eBDDE\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAntioxidant\u003c\/th\u003e\u003ctd\u003eMannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eIPN-Like (cross-linking) \u0026middot; Bi-SOFT\u0026reg; syringe\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003epH\u003c\/th\u003e\u003ctd\u003e7.2 (phosphate buffer)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 0.8 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e4 sterile single-use needles (gauge not specified in the instructions for use)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eSuperficial to mid dermis; labial mucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe) \/ irradiation or ethylene oxide (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device in accordance with Directive 93\/42\/EEC; notified body 0344. According to the instructions for use, STYLAGE\u0026reg; S obtained the CE mark in 2008\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTraceability\u003c\/th\u003e\u003ctd\u003eVIVACY remote authentication system with RFID technology\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e in its original packaging between 2 \u0026deg;C and 25 \u0026deg;C, protected from freezing and from light. Failure to comply with the storage conditions may affect the performance of the product.\u003c\/li\u003e\n\u003cli\u003eIf it has been kept in a refrigerator, allow the product to reach room temperature before injection.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack and on the syringe. Do not use if the packaging is damaged.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise, even if the implant has not been injected. Inject immediately after opening.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 0.8 ml, 4 sterile single-use needles, instructions for use and labels with the batch number \u0026mdash; one for the patient and one for the medical record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIt must not be used:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ein association with a peel, a laser treatment or dermabrasion (the practitioner decides the waiting period required after these treatments)\u003c\/li\u003e\n\u003cli\u003ein patients with a tendency to develop hypertrophic scars\u003c\/li\u003e\n\u003cli\u003ein patients with known hypersensitivity to any of the components\u003c\/li\u003e\n\u003cli\u003ein pregnant or breastfeeding women, or in children\u003c\/li\u003e\n\u003cli\u003ein areas, or in the vicinity of areas, with inflammatory or infectious skin problems (acne, herpes, etc.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003ePrecautions for use:\u003c\/b\u003e obtaining the patient's informed consent is strongly recommended. In patients with a history of herpes, the punctures may trigger a new outbreak. In patients with a declared or previous autoimmune disease, the practitioner must decide case by case, propose a prior double test and not inject if the disease is progressive. Patients with a history of streptococcal disease (recurrent tonsillitis, rheumatic fever) must undergo a prior double test; in the case of rheumatic fever with cardiac involvement, injection is not recommended. In the case of a haemostasis disorder or anticoagulant therapy the risk of haematomas is increased. The intake of aspirin, NSAIDs, antiplatelet agents, anticoagulants or vitamin C should be avoided in the week preceding the injection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eVascular risk:\u003c\/b\u003e do not inject into blood vessels. An accidental intravascular injection may cause vascular occlusion with rare but serious complications —visual disturbances, blindness, necrosis of the skin and\/or of the underlying tissues— depending on the area injected. Do not inject into nerves: accidental nerve injury may cause transient paraesthesia.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment. The binding contraindications are those set out in the official documentation supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official instructions for use of Laboratoires VIVACY (OPDC340 v4) and on the manufacturer's technical documentation. This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Vivacy","offers":[{"title":"Default Title","offer_id":51060744716628,"sku":"STY005","price":86.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/stylage_s_17e0487d-4ebe-4378-973b-c8b9ad3f1ca7.jpg?v=1747757713"},{"product_id":"ialest","title":"Ialest 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eIalest is the non-cross-linked hyaluronic acid solution from Mastelli S.r.l.: 20 mg\/ml (2 %) of sodium hyaluronate in a 2 ml pre-filled syringe. It is the only product in the Mastelli range that \u003cb\u003econtains no polynucleotides\u003c\/b\u003e: it acts through hydration and improvement of the viscoelastic properties of the extracellular matrix, not through biostimulation with PN-HPT®.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 20 mg\/ml (2 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout polynucleotides\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked sodium hyaluronate:\u003c\/b\u003e 20 mg\/ml, that is 40 mg per 2 ml syringe (2 %).\u003c\/li\u003e\n\u003cli\u003eSterile, pyrogen-free, viscoelastic and transparent solution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism of action:\u003c\/b\u003e hyaluronic acid is an essential component of the extracellular matrix and determines much of its mechanical and elastic properties. As it is not cross-linked, it generates neither volume nor projection: it distributes within the dermis, binds water and additionally acts as a free radical scavenger. With age, the physiological concentration of hyaluronic acid decreases, and this supplementation aims to restore hydration and turgor.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout polynucleotides, without anaesthetic.\u003c\/b\u003e For biostimulation with PN-HPT®, the reference within the range is Plinest; for the combination of both active ingredients in a single syringe, Newest.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Mastelli range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePlinest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 20 mg\/ml (40 mg \/ 2 ml) — 1 syringe of 2 ml. High concentration: face, neck, décolleté and dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Fast\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml (15 mg \/ 2 ml) — 1 syringe of 2 ml. Low concentration for thin or sensitive skin and for skin preparation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Eye\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Periocular indication\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Hair\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Indication for scalp, eyebrows and beard\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® 2 mg\/ml (8 mg per 4 ml vial) — 5 vials of 4 ml. Diluted formulation for large surfaces and the body\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 10 mg\/ml + non-cross-linked HA 10 mg\/ml + mannitol — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® + non-cross-linked HA + mannitol in a diluted formulation — 5 vials of 4 ml, body and large surfaces\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIalest\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 20 mg\/ml (2 %), without polynucleotides — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eIalest is the pure hydration product of the range: it provides twice as much hyaluronic acid as Newest (20 versus 10 mg\/ml), but no polynucleotides. Plenhyage XL Strong, which is marketed alongside this range, \u003cb\u003edoes not belong to the Mastelli family\u003c\/b\u003e: it is a brand of Bioformula S.r.l.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eDehydrated skin with loss of turgor\u003c\/li\u003e\n\u003cli\u003eLoss of elasticity and superficial wrinkles associated with skin ageing\u003c\/li\u003e\n\u003cli\u003eScar remodelling, including acne sequelae\u003c\/li\u003e\n\u003cli\u003eImprovement of skin nutrition and texture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eAreas:\u003c\/b\u003e face, neck, décolleté and dorsum of the hands.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits (multi-puncture) or linear retrograde threading with a needle, depending on the area.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 30G ½\" (13 mm); 2 units are included.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose and number of sessions:\u003c\/b\u003e the volume per session and the number of sessions are adjusted to the practitioner's judgement and to the area treated. Mastelli does not publish a fixed protocol for this reference; follow the one stated in the instructions for use in the packaging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMastelli S.r.l., Sanremo (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eNon-cross-linked sodium hyaluronate 20 mg\/ml (2 %)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eContent per syringe\u003c\/th\u003e\u003ctd\u003e40 mg of hyaluronic acid in 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\" (13 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked class III medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight and heat sources. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the packaging.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 1 pre-filled syringe of 2 ml, 2 needles 30G ½\", instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases; active skin infection or inflammation in the treatment area, including active herpes simplex; coagulation disorders or anticoagulant therapy; ongoing oncological treatment; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eDo not apply over areas with permanent implants or non-resorbable filler material without prior assessment.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use enclosed in the packaging before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the documentation of Mastelli S.r.l. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Mastelli","offers":[{"title":"Default Title","offer_id":51088211280212,"sku":"IAL001","price":76.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/ialest.jpg?v=1747753562"},{"product_id":"newest","title":"Newest Polynucleotides 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eNewest® is the hybrid product from Mastelli S.r.l.: it combines PN-HPT® polynucleotides at 10 mg\/ml with non-cross-linked hyaluronic acid at 10 mg\/ml and mannitol in a single 2 ml syringe. It brings together in one session the fibroblast biostimulation characteristic of polynucleotides and the immediate hydration of free hyaluronic acid, without adding volume.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT®\u003c\/b\u003e 10 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 10 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3–4 sessions \/ 14–21 days\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT® polynucleotides:\u003c\/b\u003e 10 mg\/ml (20 mg per 2 ml syringe).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 10 mg\/ml (20 mg per 2 ml syringe). This is the distinguishing element of Newest compared with the Plinest line, which contains no hyaluronic acid.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMannitol:\u003c\/b\u003e included in the formulation as an antioxidant excipient.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOrigin of the polynucleotides:\u003c\/b\u003e trout gonads from aquaculture intended for human consumption, subjected to Mastelli's proprietary high-purification process, which removes proteins and contaminants of potential allergenic character.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism of action:\u003c\/b\u003e the polynucleotides stimulate the fibroblast to synthesise glycosaminoglycans, collagen and elastin and bind water in the extracellular matrix; the free hyaluronic acid provides hydration from the first session and improves the viscoelastic properties of the dermis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Mastelli range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePlinest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 20 mg\/ml (40 mg \/ 2 ml) — 1 syringe of 2 ml. High concentration: face, neck, décolletage and dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Fast\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml (15 mg \/ 2 ml) — 1 syringe of 2 ml. Low concentration for thin or sensitive skin and for skin preparation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Eye\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Periocular indication\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Hair\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Indication for the scalp, eyebrows and beard\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® 2 mg\/ml (8 mg per 4 ml vial) — 5 vials of 4 ml. Diluted formulation for large surfaces and the body\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 10 mg\/ml + non-cross-linked HA 10 mg\/ml + mannitol — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® + non-cross-linked HA + mannitol in diluted formulation — 5 vials of 4 ml, body and large surfaces\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIalest\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 20 mg\/ml (2 %), without polynucleotides — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe range is ordered by two criteria: \u003cb\u003epresence or absence of hyaluronic acid\u003c\/b\u003e (Newest line versus Plinest line; Ialest hyaluronic acid only) and \u003cb\u003econcentration\u003c\/b\u003e. Newest is the only 2 ml syringe that combines both active substances. Plenhyage XL Strong, which is marketed alongside this range, \u003cb\u003edoes not belong to the Mastelli family\u003c\/b\u003e: it is a brand of Bioformula S.r.l.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eMature and dehydrated skin\u003c\/li\u003e\n\u003cli\u003eLoss of firmness, elasticity and skin density\u003c\/li\u003e\n\u003cli\u003eFine lines and superficial wrinkles\u003c\/li\u003e\n\u003cli\u003eOverall improvement in skin quality and appearance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eAreas:\u003c\/b\u003e face, neck, décolletage and dorsum of the hands.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits (multiple puncture), linear retrograde or fanning.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 30G ½\" (13 mm); 2 units included.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e 2 ml per session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e 3 sessions at intervals of 14 to 21 days in younger patients; 4 sessions at the same interval in advanced skin ageing.\u003c\/li\u003e\n\u003cli\u003eCompatible with combined protocols within the Mastelli range and with other medical aesthetic treatments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMastelli S.r.l., Sanremo (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substances\u003c\/th\u003e\u003ctd\u003ePN-HPT® polynucleotides 10 mg\/ml + non-cross-linked hyaluronic acid 10 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOther components\u003c\/th\u003e\u003ctd\u003eMannitol\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin of the polynucleotides\u003c\/th\u003e\u003ctd\u003eTrout gonads from aquaculture, highly purified\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\" (13 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device with CE marking 0373\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight and heat sources. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2 ml, 2 needles 30G ½\", instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases; active skin infection or inflammation in the treatment area, including active herpes simplex; coagulation disorders or anticoagulant therapy; ongoing oncological treatment; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eAs this is a product of fish origin, assess any history of fish allergy before application.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the documentation of Mastelli S.r.l. and on the published clinical literature on PN-HPT®. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Mastelli","offers":[{"title":"Default Title","offer_id":51088285466964,"sku":"NEW002","price":80.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/newest.jpg?v=1747753369"},{"product_id":"aesplla-365mg","title":"Aesplla Poly-L-Lactic Acid 1x365mg","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eaesPlla® is a lyophilised collagen biostimulator from Oreon Life Science (South Korea) based on poly-L-lactic acid microspheres. It does not provide immediate volume: the PLLA acts as a matrix that stimulates the dermal fibroblasts to produce the patient's own collagen, with a result that develops progressively. The 365 mg vial contains 150 mg of PLLA and is reconstituted with 5 ml of sterile water for injection, with a dissolution time of 3 hours.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003ePLLA\u003c\/b\u003e 150 mg per vial\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVial\u003c\/b\u003e 365 mg of lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReconstitution\u003c\/b\u003e 5 ml of sterile water\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDissolution\u003c\/b\u003e 3 hours\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApplication\u003c\/b\u003e cannula or 26G needle\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePoly-L-lactic acid (PLLA):\u003c\/b\u003e 150 mg per vial, in microspheres.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eSodium carboxymethylcellulose:\u003c\/b\u003e 90 mg — suspending agent that keeps the microspheres dispersed after reconstitution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMannitol:\u003c\/b\u003e 125 mg — bulking agent and cryoprotectant for the lyophilisation process.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTotal vial content:\u003c\/b\u003e 365 mg of lyophilised powder.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism:\u003c\/b\u003e the PLLA microspheres provoke a controlled tissue remodelling response that induces collagen synthesis by the dermal fibroblasts. The polymer degrades by hydrolysis to lactic acid and is eliminated by metabolic pathways; the observed effect is that of the newly formed collagen, not of the implanted material.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOrigin:\u003c\/b\u003e synthetic polymer. It contains no protein of animal or human origin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable biostimulator indicated for volume restoration and the correction of deep dermal deficits in adult patients.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFacial wrinkles, from superficial to deep\u003c\/li\u003e\n\u003cli\u003eNasolabial fold and marionette lines\u003c\/li\u003e\n\u003cli\u003eTemporal region and cheekbones\u003c\/li\u003e\n\u003cli\u003eJawline and laxity of the contour (jowls)\u003c\/li\u003e\n\u003cli\u003eDeep dermal volume deficit\u003c\/li\u003e\n\u003cli\u003eScars\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eReconstitution and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eReconstitution determines the result and the safety profile of the product.\u003c\/b\u003e Insufficient hydration or a non-homogeneous suspension is the principal cause of nodules with PLLA biostimulators.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eDiluent:\u003c\/b\u003e 5 ml of sterile water for injection, introduced with an 18G needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDissolution time:\u003c\/b\u003e 3 hours before application.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eStability after reconstitution:\u003c\/b\u003e the reconstituted product must be used within 72 hours.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLoading:\u003c\/b\u003e draw up with an 18G needle into 1 or 3 ml syringes.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis, lower layers of the dermis or hypodermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApplication:\u003c\/b\u003e cannula or 26G needle, with a retrograde linear threading technique.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePost-treatment massage:\u003c\/b\u003e massage the treated area after the session to distribute the microspheres evenly and reduce the risk of nodules.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOnset of the result:\u003c\/b\u003e from 4 weeks after application, progressively.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e the manufacturer states a persistence of the result of up to 36 months.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe manufacturer does not publish a fixed number of sessions or a defined interval between them. The regimen is established according to clinical assessment and the degree of correction achieved; consult the instructions for use accompanying the batch.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eOreon Life Science Co., Ltd. — South Korea\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003ePoly-L-lactic acid (PLLA) 150 mg\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExcipients\u003c\/th\u003e\u003ctd\u003eSodium carboxymethylcellulose 90 mg, mannitol 125 mg\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 vial of 365 mg of lyophilised powder\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eReconstitution\u003c\/th\u003e\u003ctd\u003e5 ml of sterile water for injection (18G needle)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDissolution time\u003c\/th\u003e\u003ctd\u003e3 hours\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse after reconstitution\u003c\/th\u003e\u003ctd\u003eWithin 72 hours\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eDeep dermis \/ hypodermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication\u003c\/th\u003e\u003ctd\u003eCannula or 26G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eExclusively qualified healthcare professionals with specific training in PLLA\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e at room temperature. \u003cb\u003eDo not refrigerate.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eReconstituted product:\u003c\/b\u003e use within the following 72 hours.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 vial of 365 mg of lyophilised powder and instructions for use. The diluent, syringes and needles are not included.\u003c\/li\u003e\n\u003cli\u003ePrepare the reconstitution under aseptic conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to polylactic acid or to any of the excipients; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; active autoimmune disease; tendency to hypertrophic or keloid scarring; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings specific to PLLA biostimulators:\u003c\/b\u003e do not inject into the lips or into the periorbital region. Injection that is too superficial, incomplete hydration of the product, a non-homogeneous suspension or insufficient massage after the session are associated with the formation of late nodules and papules. Do not overcorrect: the effect is not immediate and is assessed after weeks, not in the same session.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNever inject intravascularly.\u003c\/b\u003e Always consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eProduct intended exclusively for qualified healthcare professionals with specific training in polylactic acid biostimulators. Technical information based on the documentation of the manufacturer Oreon Life Science and of its official distribution. The reconstitution and application parameters must be taken from the instructions for use accompanying each batch; this data sheet does not replace them.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Orean Life Science","offers":[{"title":"Default Title","offer_id":51727863316820,"sku":"AES001","price":134.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/aesplla_0a8fe756-276f-4c2b-9375-3dce6ba1bab6.jpg?v=1747839099"},{"product_id":"gouri-1x-1-0-ml","title":"Gouri 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eGOURI® from Dexlevo (South Korea) is the first injectable polycaprolactone (PCL) biostimulator in \u003cb\u003efully liquid form\u003c\/b\u003e, without microspheres or suspended particles. This absence of particles is its defining feature: the product distributes itself within the tissue plane, allows the use of very fine needles and requires no subsequent manual moulding. It is applied using a scheme of points distributed across the whole face for global biostimulation, rather than as a localised volumising filler.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eActive ingredient\u003c\/b\u003e liquid PCL 21 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eFormat\u003c\/b\u003e particle-free\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 30G–35G\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e deep dermis \/ subdermal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePolycaprolactone (PCL) at 21 %\u003c\/b\u003e, in liquid, solubilised form.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCESABP technology\u003c\/b\u003e (\u003ci\u003eCollagen Enabled Solubilized Active and Biodegradable Polymer\u003c\/i\u003e): Dexlevo's patented technology, which makes it possible to present the polymer in liquid, solubilised form instead of as microspheres suspended in a gel.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism:\u003c\/b\u003e the polymer induces neocollagenesis in the tissue in which it is deposited. As it is not particulate, it distributes diffusely throughout the injection plane rather than concentrating in discrete deposits, which underpins the manufacturer's global rejuvenation approach.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBiodegradation:\u003c\/b\u003e PCL is degraded by hydrolysis; the manufacturer places the polymer degradation period at between 6 and 12 months.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eImportant note:\u003c\/b\u003e GOURI is \u003cb\u003enot\u003c\/b\u003e a poly-L-lactic acid (PLLA) product. Its active ingredient is polycaprolactone (PCL), a different polymer, and its formulation is liquid, without the microspheres characteristic of PLLA biostimulators. It also requires no reconstitution or prior hydration time.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable biostimulator indicated for global facial rejuvenation in adult patients.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eModerate to marked signs of facial ageing\u003c\/li\u003e\n\u003cli\u003eLoss of skin firmness and elasticity\u003c\/li\u003e\n\u003cli\u003eDiffuse skin laxity\u003c\/li\u003e\n\u003cli\u003eGlobal improvement of facial skin quality\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe manufacturer states that clinical data for other areas — neck and dorsum of the hands — are still being collected, and these areas are therefore not presented here as an established indication.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNo reconstitution:\u003c\/b\u003e the product is supplied ready to use in a pre-filled syringe. It requires no dilution or prior standing time.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis or subdermal plane.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 30G to 35G. The absence of particles is what allows such fine gauges to be used; it may also be applied by cannula according to operator preference.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApplication scheme:\u003c\/b\u003e the manufacturer's protocol distributes the product across \u003cb\u003edefined anatomical points per hemiface\u003c\/b\u003e — frontal region, medial cheek, lateral cheek, perioral region and periocular region — up to a total of 10 points on the whole face, in order to achieve homogeneous distribution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNo subsequent moulding:\u003c\/b\u003e being a non-particulate liquid formulation, it requires no shaping massage after injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNumber of sessions:\u003c\/b\u003e the manufacturer states that \u003cb\u003eone session\u003c\/b\u003e is sufficient in most cases, with the option of 1 or 2 additional sessions 4 to 6 weeks apart in more severe cases.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOnset of result:\u003c\/b\u003e first visible changes in 1 to 2 weeks, with progressive improvement through neocollagenesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe manufacturer does not publish a fixed volume per injection point; the figures circulating in distribution documentation are inconsistent and are therefore not reproduced here. Take the dosage from the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eDexlevo Inc. — South Korea\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredient\u003c\/th\u003e\u003ctd\u003eLiquid polycaprolactone (PCL) at 21 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eForm\u003c\/th\u003e\u003ctd\u003eSolubilised liquid solution, without microspheres or particles\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eCESABP\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e30G–35G (alternatively cannula)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eDeep dermis \/ subdermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eReconstitution\u003c\/th\u003e\u003ctd\u003eNot required\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolymer degradation\u003c\/th\u003e\u003ctd\u003e6–12 months according to the manufacturer\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device. Manufactured under ISO 13485\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e store in the original packaging under the temperature conditions stated on it, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the packaging.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack includes:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, needles and instructions for use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to polycaprolactone or to any of the components of the formulation; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; active autoimmune disease; tendency to hypertrophic or keloid scarring; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e do not apply in areas with pre-existing permanent implants. Do not combine in the same session with ablative laser, deep peeling or dermabrasion. Assess individually in patients on anticoagulant or antiplatelet therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNever inject intravascularly.\u003c\/b\u003e Observe the stated injection plane. Always consult the instructions for use enclosed in the packaging before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of the manufacturer Dexlevo and its distribution. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Dexlevo","offers":[{"title":"Default Title","offer_id":51727953428820,"sku":"GOU001","price":112.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/gouri.jpg?v=1745230340"},{"product_id":"saypha-volume","title":"Croma Saypha Volume 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSaypha® Volume is the cross-linked hyaluronic acid filler from Croma-Pharma for the correction of severe nasolabial folds, in its version \u003cb\u003ewithout anaesthetic\u003c\/b\u003e. It shares gel, concentration (23 mg\/ml) and degree of cross-linking (0.5–1.5 %) with Saypha Volume with lidocaine; the only difference is the absence of lidocaine, which allows the anaesthetic protocol to be chosen freely (topical, nerve block or prior infiltration).\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 23 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e 0.5–1.5 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAnaesthetic\u003c\/b\u003e without lidocaine\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\"\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 23 mg\/ml, of non-animal origin obtained by bacterial fermentation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e 0.5–1.5 %, higher than that of Saypha Filler. At the same HA concentration, a higher cross-linking density increases the gel's resistance to deformation and its persistence in deep planes.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout anaesthetic:\u003c\/b\u003e lidocaine-free formulation. Indicated where there is allergy or intolerance to amide-type local anaesthetics, or when the practitioner prefers to manage anaesthesia separately.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturing:\u003c\/b\u003e in-house production by Croma-Pharma in Leobendorf (Austria), pre-filled syringe sterilised by moist heat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Saypha variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Filler (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — moderate nasolabial folds, mid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.5 % — severe nasolabial folds, deep dermis and subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume Plus lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml, cross-linking 1.0–2.0 % — volume deficit of the midface, deep subcutaneous or supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Lips lidocaine\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — lip augmentation, submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Rich\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 18 mg\/ml + glycerol — skin revitalisation in the superficial dermis. It is not a volumising filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable hyaluronic acid implant indicated by the manufacturer for the correction of \u003cb\u003esevere nasolabial folds\u003c\/b\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSevere nasolabial folds\u003c\/li\u003e\n\u003cli\u003eDeep folds of the lower facial third\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor volume deficit of the midface, the range provides Saypha Volume Plus, with a higher concentration and degree of cross-linking.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep dermis and subcutaneous tissue.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 × 27G ½\" thin wall Terumo™.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAnaesthesia:\u003c\/b\u003e as it does not contain lidocaine, prior topical anaesthesia or nerve block is recommended according to the area and the patient's sensitivity.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e linear retrograde or fanning, with slow injection and prior aspiration according to clinical protocol.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e in the clinical study of the Saypha range in nasolabial folds the correction was maintained for up to 9 months.\u003c\/li\u003e\n\u003cli\u003eNever inject intravascularly. Do not apply over areas with permanent implants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Leobendorf, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 23 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e0.5–1.5 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\" thin wall Terumo™\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDeep dermis, subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device, CE mark 0123 (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 27G ½\", instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins; active autoimmune disease; tendency to hypertrophic or keloid scarring; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e anticoagulant or antiplatelet therapy; history of severe allergic reactions; areas with permanent implants. Do not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma (Saypha portfolio brochure). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51729584521556,"sku":"SAY004","price":64.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/saypha_volume.jpg?v=1745240570"},{"product_id":"saypha-volume-plus-lidocaina","title":"Croma Saypha Volume Plus Lidocaine 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eSaypha® Volume Plus with lidocaine is the densest gel of the Croma-Pharma injectable range: 25 mg\/ml of hyaluronic acid with a degree of cross-linking of 1.0–2.0 %. It is the only Saypha variant indicated for volume deficit of the midface and the only one applied in the deep subcutaneous or supraperiosteal plane.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 25 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linking\u003c\/b\u003e 1.0–2.0 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 0.3 %\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\"\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 25 mg\/ml, of non-animal origin obtained by bacterial fermentation. It is the highest concentration in the Saypha range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDegree of cross-linking:\u003c\/b\u003e 1.0–2.0 %, between two and four times higher than that of Saypha Filler. Hence its greater capacity to sustain volume and projection against tissue pressure.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine:\u003c\/b\u003e 0.3 % (3 mg\/ml), incorporated into the gel to reduce discomfort during injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eManufacturing:\u003c\/b\u003e in-house production by Croma-Pharma in Leobendorf (Austria), pre-filled syringe sterilised by moist heat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Saypha variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Filler (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — moderate nasolabial folds, mid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume (± lidocaine)\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.5 % — severe nasolabial folds, deep dermis and subcutis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Volume Plus lidocaine\u003c\/th\u003e\u003ctd\u003eHA 25 mg\/ml, cross-linking 1.0–2.0 % — volume deficit of the midface, deep subcutaneous or supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Lips lidocaine\u003c\/th\u003e\u003ctd\u003eHA 23 mg\/ml, cross-linking 0.5–1.0 % — lip augmentation, submucosa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSaypha Rich\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 18 mg\/ml + glycerol — skin revitalisation in the superficial dermis. It is not a volumising filler\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable implant indicated by the manufacturer for the correction of \u003cb\u003emoderate to severe volume deficit of the midface\u003c\/b\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMalar region and cheekbones\u003c\/li\u003e\n\u003cli\u003eProjection of the midface\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e deep subcutaneous tissue and\/or supraperiosteal.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 × 27G ½\" thin wall Terumo™.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e supraperiosteal deposits or linear retrograde injection in the deep plane, with prior aspiration and slow injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration:\u003c\/b\u003e in the manufacturer's clinical study in the midface, the result was maintained up to month 13.\u003c\/li\u003e\n\u003cli\u003eNever inject intravascularly. Do not apply over areas with permanent implants.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Leobendorf, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 25 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eDegree of cross-linking\u003c\/th\u003e\u003ctd\u003e1.0–2.0 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine 0.3 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\" thin wall Terumo™\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eDeep subcutaneous and\/or supraperiosteal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device, CE mark 0123 (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 1.0 ml, 2 needles 27G ½\", instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to Gram-positive bacterial proteins; allergy to lidocaine or to amide-type local anaesthetics; porphyria; active autoimmune disease; tendency to hypertrophic or keloid scarring; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e anticoagulant or antiplatelet therapy; history of severe allergic reactions; areas with permanent implants. Injection in the deep planes of the midface requires detailed knowledge of the vascular anatomy. Do not combine in the same session with laser, deep peeling or dermabrasion.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma (Saypha portfolio brochure). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51729603428692,"sku":"SAY006","price":72.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/saypha_volume_plus.jpg?v=1745240701"},{"product_id":"profhilo-structura-1x-2-0ml","title":"Profhilo Structura 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eProfhilo® Structura from IBSA Derma is the variant of the Profhilo range aimed at volume loss due to atrophy of facial adipose tissue. It concentrates 90 mg of \u003cb\u003enon-cross-linked\u003c\/b\u003e hyaluronic acid in 2 ml — 45 mg of high molecular weight and 45 mg of low molecular weight — stabilised by NAHYCO® thermal technology. Unlike Profhilo H+L, which acts in the dermal plane, Structura is applied with a cannula in the superficial fat compartment.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 90 mg \/ 2 ml (4.5 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eH-HA + L-HA\u003c\/b\u003e 45 mg + 45 mg\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApplication\u003c\/b\u003e with cannula, superficial fat plane\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 2 sessions \/ 30 days\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eHigh molecular weight hyaluronic acid (H-HA):\u003c\/b\u003e 45 mg per 2 ml syringe, 1,100–1,400 kDa.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLow molecular weight hyaluronic acid (L-HA):\u003c\/b\u003e 45 mg per 2 ml syringe, 80–100 kDa.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTotal concentration:\u003c\/b\u003e 90 mg \/ 2 ml, equivalent to 45 mg\/ml (4.5 %). This is the highest concentration in the Profhilo range.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNAHYCO® technology:\u003c\/b\u003e patented thermal process that combines the two molecular weight fractions by controlled heating and cooling. As the hydrogen bonds break and re-form, stable Hybrid Cooperative Complexes (\u003ci\u003eHybrid Cooperative Complexes\u003c\/i\u003e, HCC) are generated. \u003cb\u003eWithout BDDE or any other chemical cross-linking agent.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G' of approximately 95 Pa. A deliberately low value compared with that of a volumetric filler: the objective is not mechanical projection, but integration into the fat compartment.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDifferentiating mechanism:\u003c\/b\u003e the manufacturer describes an action restoring adipose tissue (\u003ci\u003elipolifting\u003c\/i\u003e), aimed at the age-related atrophy of the facial fat compartments, and not at volume replacement by implant.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between the Profhilo variants\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo H+L\u003c\/th\u003e\u003ctd\u003e64 mg \/ 2 ml (32 mg H-HA + 32 mg L-HA) — laxity and remodelling of the facial contour, dermal\/subcutaneous plane, BAP technique with a 29G needle\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Structura\u003c\/th\u003e\u003ctd\u003e90 mg \/ 2 ml (45 mg H-HA + 45 mg L-HA) — atrophy of facial adipose tissue, superficial fat compartment, retrograde application with a cannula\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProfhilo Body\u003c\/th\u003e\u003ctd\u003e96 mg \/ 3 ml per syringe, 2 syringes — body skin laxity (abdomen, inner surface of the arms, knees), body BAP technique at 10 points\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eAll three variants share NAHYCO® technology and the absence of a chemical cross-linker. They differ in concentration, application plane and pattern of points. Structura and H+L are not interchangeable: they treat different anatomical planes and can be used complementarily.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eIndicated for the \u003cb\u003erestoration of facial adipose tissue\u003c\/b\u003e in patients with signs of structural ageing due to atrophy of the fat compartments.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLateral fat compartment of the cheek\u003c\/li\u003e\n\u003cli\u003ePreauricular region\u003c\/li\u003e\n\u003cli\u003eZygomatic arch\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eProduct for facial use only. The range does not currently provide a body indication for this reference; Profhilo Body is used for the body.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e superficial fat compartment (subcutaneous plane), one layer below the dermal plane in which Profhilo H+L is applied.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e retrograde injection \u003cb\u003ewith a cannula\u003c\/b\u003e, not with a needle. A pilot needle is used to create the entry point.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e\"Deflation\" pattern (predominant volume loss):\u003c\/b\u003e 22G × 50 mm cannula, entry point approximately 2 cm from the tragus, 1 ml per hemiface deposited in the preauricular region.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003e\"Sagging\" pattern (predominant laxity):\u003c\/b\u003e 25G × 38 mm cannula, entry point approximately 3 cm from the tragus, 0.5 ml in the preauricular region and 0.5 ml in the zygomatic arch per hemiface.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e 2 ml per session, that is, one complete syringe (1 ml per hemiface).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e two sessions with an interval of 30 days.\u003c\/li\u003e\n\u003cli\u003eCompatible with combined protocols within the IBSA Derma range; the sequence with cross-linked fillers or with Profhilo H+L should be planned according to clinical judgement.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eIBSA Derma — IBSA Institut Biochimique SA, Switzerland\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eSodium salt of non-cross-linked hyaluronic acid, 90 mg \/ 2 ml (45 mg\/ml)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eFractions\u003c\/th\u003e\u003ctd\u003e45 mg H-HA (1,100–1,400 kDa) + 45 mg L-HA (80–100 kDa)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linker\u003c\/th\u003e\u003ctd\u003eNone — NAHYCO® thermal stabilisation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheological profile\u003c\/th\u003e\u003ctd\u003eG' ≈ 95 Pa\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eCannula, superficial fat plane (subcutaneous)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 0 °C and 25 °C, away from heat sources. \u003cb\u003eDo not freeze.\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise. Sterile and pyrogen-free contents.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2.0 ml, administration material, instructions for use and traceability labels for the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eManufacturer's warnings:\u003c\/b\u003e do not inject intravenously, intramuscularly or into tendons. Do not mix with other products in the same syringe. It must not be used concomitantly with laser \u003ci\u003eresurfacing\u003c\/i\u003e treatments or with medium-to-deep peels. After injection it is recommended to avoid exposure to ultraviolet radiation for 3–5 days and to use SPF 50 sun protection.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e known hypersensitivity to hyaluronic acid or to any of the components; active skin infection or inflammation in the treatment area; pregnancy and breastfeeding; patients under 18 years of age. Individual assessment in patients with autoimmune disease, coagulation disorders or anticoagulant therapy.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of IBSA Derma and on specialist publications on the Profhilo range. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"IBSA","offers":[{"title":"Default Title","offer_id":51737317769556,"sku":"PRO003","price":148.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/profhilo_structura.jpg?v=1745315356"},{"product_id":"polyphil-next","title":"Croma PolyPhil Next 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eCroma PolyPhil™ Next is the hybrid biostimulator of Croma-Pharma's polynucleotide range: it combines 20 mg of PN-HPT® polynucleotides with 20 mg of non-cross-linked hyaluronic acid in a single 2 ml syringe. Dermal biostimulation and immediate hydration in one product, formulated for mature, dehydrated skin and for the treatment of scars.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT®\u003c\/b\u003e 20 mg \/ 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 20 mg \/ 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3 sessions\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT® polynucleotides:\u003c\/b\u003e 20 mg per 2 ml syringe (10 mg\/ml), obtained from freshwater trout from controlled European aquaculture, with full traceability of the production chain.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 20 mg per 2 ml syringe (10 mg\/ml). This is the distinguishing element of the Next variant compared with classic PolyPhil.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT® (Polynucleotide High Purification Technology):\u003c\/b\u003e Croma's proprietary purification process, which guarantees a high degree of purity of the polynucleotide chain.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism of action:\u003c\/b\u003e the polynucleotides stimulate fibroblast proliferation and the neosynthesis of collagen and elastin, retain water and act as free-radical scavengers, creating an optimal environment for fibroblast activity. The free hyaluronic acid provides immediate hydration and improves skin quality from the first session.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the PolyPhil range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil\u003c\/th\u003e\u003ctd\u003ePN-HPT® 40 mg \/ 2 ml, without HA — face, neck, décolletage, hands, scars\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Next\u003c\/th\u003e\u003ctd\u003ePN-HPT® 20 mg + HA 20 mg \/ 2 ml — mature and dehydrated skin, mid third of the face, scars and acne scars\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Eye\u003c\/th\u003e\u003ctd\u003ePN-HPT® 15 mg \/ 2 ml — eye contour, eyelids, superficial lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Hair\u003c\/th\u003e\u003ctd\u003ePN-HPT® 15 mg \/ 2 ml — scalp and eyebrows\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eNote: the PhilArt line was renamed PolyPhil™ in 2024\/2025. It is the same product and the same formulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eMature and dehydrated skin\u003c\/li\u003e\n\u003cli\u003eMid third of the face\u003c\/li\u003e\n\u003cli\u003eScars and acne scars\u003c\/li\u003e\n\u003cli\u003eFace, neck and dorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAlso indicated as a skin conditioning technique (SET, \u003ci\u003eSkin Enhancement Technique\u003c\/i\u003e) prior to laser treatment, peeling, microneedling or PRP.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal — superficial, mid or deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits (multiple puncture), linear retrograde or fanning, with a needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended needle:\u003c\/b\u003e 30G ½\" (13 mm), 2 units included.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e 2 ml per session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e 3 sessions at intervals of 14 to 21 days in normal skin; 4 sessions in advanced skin ageing.\u003c\/li\u003e\n\u003cli\u003eCompatible with combined protocols within the PolyPhil range and with other medical aesthetic treatments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substances\u003c\/th\u003e\u003ctd\u003ePN-HPT® polynucleotides 10 mg\/ml + non-cross-linked hyaluronic acid 10 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin of the polynucleotides\u003c\/th\u003e\u003ctd\u003eFreshwater trout, controlled European aquaculture\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\" (13 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eIntradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking 0373\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, in a dry place protected from sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2 ml, 2 needles 30G ½\", user information and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases or a history of them; active skin infection or inflammation in the treatment area, including active herpes simplex; coagulation disorders; epilepsy; circulatory disorders; ongoing antibiotic or oncological treatment; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51746430058836,"sku":"POL004","price":98.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/polyphil.jpg?v=1745412008"},{"product_id":"rich-pl-topic-1x-15ml","title":"RICH PL Topical 1x15ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRICH PL Topic is a professional cosmetic product from Promoitalia for \u003cb\u003etopical use\u003c\/b\u003e: it is not an injectable. It combines 20 mg of polylactic acid (PLA) of medium polymerisation, stabilised within a matrix of hyaluronic acid cross-linked with BDDE at 10 mg\/ml. The manufacturer describes it as the first ready-to-use liquid cosmetic collagen stimulator; the cross-linked matrix protects the PLA polymer from premature hydrolytic degradation.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003ePolylactic acid\u003c\/b\u003e 20 mg\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA (BDDE)\u003c\/b\u003e 10 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRoute\u003c\/b\u003e topical — not injectable\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePresentation\u003c\/b\u003e 1 vial (10 ml according to the manufacturer)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCategory\u003c\/b\u003e professional cosmetic\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePolylactic acid (PLA):\u003c\/b\u003e 20 mg, of medium degree of polymerisation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eHyaluronic acid cross-linked with BDDE:\u003c\/b\u003e 10 mg\/ml, acting as a stabilising matrix and providing hydration and elasticity support to the tissue.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTechnology:\u003c\/b\u003e the polylactic acid is stabilised within the cross-linked hyaluronic acid matrix, which — according to the manufacturer — prevents its premature hydrolytic degradation and prolongs the bioactivity of the polymer.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eEffects stated by the manufacturer:\u003c\/b\u003e deep skin hydration, improvement of tone, redensification of the dermal matrix and stimulation of collagen and elastin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eRoute of administration and regulatory status\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eRICH PL Topic is formulated and marketed by Promoitalia as a \u003cb\u003ecosmetic product for topical use\u003c\/b\u003e. It is not an injectable product and must not be administered intradermally, subcutaneously or by any other parenteral route.\u003c\/p\u003e\n\u003cp\u003eThis distinction is relevant: within the RICH PL family there are references with related compositions (PLLA, CaHA, recombinant type III collagen, free HA) whose route of administration and regulatory status vary from market to market. The \"Topic\" reference is the topical formulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIndications:\u003c\/b\u003e deep hydration, improvement of skin tone and texture, redensification of the dermal matrix and skin conditioning as an adjunct to medical aesthetic procedures.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace\u003c\/li\u003e\n\u003cli\u003eNeck and décolleté\u003c\/li\u003e\n\u003cli\u003eAreas treated with microneedling, laser or radiofrequency devices\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eTopical application on clean skin, in a clinical setting and by a professional. Ready-to-use product, with no reconstitution.\u003c\/p\u003e\n\u003cp\u003ePromoitalia does not publish in the product data sheet the dose per session, the number of sessions or the interval between them for this reference. The binding protocol is the one set out in the instructions for use included in the pack and in the manufacturer's official training.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003ePromoitalia Group, Italy\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substances\u003c\/th\u003e\u003ctd\u003ePolylactic acid (PLA) 20 mg of medium polymerisation + hyaluronic acid cross-linked with BDDE 10 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 vial. The manufacturer states a content of 10 ml per vial; check the volume indicated on the pack received\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eTopical\u003c\/b\u003e — not injectable\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCosmetic product for professional use\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eProfessional use only, in a clinical setting\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e1 vial of ready-to-use product.\u003c\/li\u003e\n\u003cli\u003eStore in a cool, dry place, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eWarnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eFor topical use only. Do not inject. Do not apply to skin with active infection, inflammation or lesions. Discontinue application in the event of a skin reaction. Avoid contact with the eyes and mucous membranes.\u003c\/p\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components, including BDDE, contraindicates its use. Always consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eCosmetic product for professional use, not injectable. Technical information based on the official documentation of Promoitalia. This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Promoitalia","offers":[{"title":"Default Title","offer_id":51749431083348,"sku":"RIC001","price":288.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/promoitalia_rich.jpg?v=1745441884"},{"product_id":"restylane-volyme","title":"Restylane Volyme 1x1ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eRestylane Volyme is Galderma's OBT™ gel intended for volume augmentation of the cheekbone. Unlike the rest of the OBT family, which works in the dermis, Volyme is implanted in the supraperiosteal or subcutaneous plane. With a G\u0026prime; of 171 Pa and a deformability of 930 %, it provides volume while preserving the flexibility of the midface in movement.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eCross-linked HA\u003c\/b\u003e 20 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine\u003c\/b\u003e 3 mg\/ml (0.3 %)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnology\u003c\/b\u003e OBT™ \/ XpresHAn™\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 1.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 27G ½\u0026quot; UTW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eCross-linked hyaluronic acid:\u003c\/b\u003e 20 mg\/ml, of non-animal origin, in phosphate buffer solution at pH 7.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eLidocaine hydrochloride:\u003c\/b\u003e 3 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOBT™ technology (Optimal Balance Technology):\u003c\/b\u003e continuous, flexible gel. Volyme is the OBT variant formulated to work in depth, not in the dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e G\u0026prime; 171 Pa at 0.1 Hz and deformability (xStrain) of 930 %. Compared with the NASHA approach to the same territory (Restylane Lyft, G\u0026prime; 799 Pa), Volyme sacrifices projection in exchange for a much more flexible behaviour under facial expression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the range: NASHA and OBT\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe entire Restylane range is built on two distinct gel technologies. Choosing between them is the first clinical decision of the treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNASHA®\u003c\/b\u003e (\u003ci\u003eNon-Animal Stabilized Hyaluronic Acid\u003c\/i\u003e): firm, particulate gels that retain the long hyaluronic acid chains with minimal cross-linking. High resistance and very low strain tolerance: projection, definition and structural support in areas that must hold their shape.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOBT™\u003c\/b\u003e (\u003ci\u003eOptimal Balance Technology\u003c\/i\u003e, marketed as \u003ci\u003eXpresHAn Technology™\u003c\/i\u003e in the United States): soft, flexible gels with a variable degree of cross-linking. Low to intermediate resistance and high strain tolerance: the gel follows the movement of the tissue, which is why it is intended for dynamic and expressive areas.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eNASHA — firmness and projection\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 416\u0026ndash;799 Pa \u0026middot; deformability 7\u0026ndash;19 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane \/ Classyc Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 701 Pa \u0026middot; 7 % \u0026mdash; wrinkles in the mid dermis, lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Lyft Lidocaine\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 799 Pa \u0026middot; 17 % \u0026mdash; cheekbones, midface, dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Eyelight\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026mdash; infraorbital hollowing, supraperiosteal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Skinboosters Vital \/ Vital Light\u003c\/th\u003e\u003ctd\u003eHA 20 and 12 mg\/ml \u0026mdash; skin quality and hydration, with no volumising purpose\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOBT \/ XpresHAn — flexibility and expression\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 70\u0026ndash;271 Pa \u0026middot; deformability 761\u0026ndash;1,442 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Refyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 70 Pa \u0026middot; 1,442 % \u0026mdash; moderate wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Kysse\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 160 Pa \u0026middot; 908 % \u0026mdash; lips, submucosal plane\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Volyme\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 171 Pa \u0026middot; 930 % \u0026mdash; malar volume, supraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRestylane Defyne\u003c\/th\u003e\u003ctd\u003eHA 20 mg\/ml \u0026middot; G\u0026prime; 271 Pa \u0026middot; 761 % \u0026mdash; severe wrinkles and folds\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe G\u0026prime; (0.1 Hz) and deformability (xStrain) values are taken from peer-reviewed literature (\u003ci\u003eJ Drugs Dermatol\u003c\/i\u003e 2024;23(12):1332\u0026ndash;1338). Galderma does not publish official rheological values.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjection into the supraperiosteal zone or into the subcutis to augment the volume of the cheeks.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCheekbones and malar region\u003c\/li\u003e\n\u003cli\u003eRestoration of midface volume\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe indication documented by the manufacturer is malar volume. Use in other areas falls outside the instructions for use and is the responsibility of the practitioner who prescribes it.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e supraperiosteal or subcutaneous. It is not indicated for dermal injection.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles included:\u003c\/b\u003e 2 units of 27G ½\u0026quot; ultra-thin wall.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e supraperiosteal bolus deposit or fanning retrograde injection in the subcutaneous plane, with low and constant pressure.\u003c\/li\u003e\n\u003cli\u003eAspiration prior to injection in accordance with standard clinical protocol; the midface is an area of significant vascular risk.\u003c\/li\u003e\n\u003cli\u003eAvoid superficial injection: it may produce visible contour irregularities.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eQ-Med AB (Galderma) \u0026mdash; Seminariegatan 21, SE-752 28 Uppsala, Sweden\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eCross-linked hyaluronic acid 20 mg\/ml, non-animal origin\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eLidocaine hydrochloride 3 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTechnology\u003c\/th\u003e\u003ctd\u003eOBT™ (XpresHAn Technology™)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eVehicle \/ pH\u003c\/th\u003e\u003ctd\u003ePhosphate buffer solution, pH 7\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRheology\u003c\/th\u003e\u003ctd\u003eG\u0026prime; 171 Pa \u0026middot; deformability 930 %\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 1.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 27G ½\u0026quot; ultra-thin wall\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eTreatment plane\u003c\/th\u003e\u003ctd\u003eSupraperiosteal or subcutaneous\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eSterilisation\u003c\/th\u003e\u003ctd\u003eMoist heat (syringe contents) \/ irradiation (needles)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device (MDR 2017\/745)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e up to 25 °C. Protect from freezing and from sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the pack.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled plastic syringe of 1.0 ml, 2 sterile needles 27G ½\u0026quot; UTW, traceability labels for the patient record and a blister pack.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications (Galderma instructions for use):\u003c\/b\u003e known hypersensitivity to streptococcal proteins or to any component of the product; history of severe allergies or of anaphylactic reaction; hypersensitivity to lidocaine or to amide-type local anaesthetics; porphyria; active skin inflammation or infection in the area to be treated.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution and individual assessment:\u003c\/b\u003e coagulation disorders or anticoagulant or antiplatelet therapy (increased risk of haematoma and bleeding at the puncture site); history of hypertrophic or keloid scarring; autoimmune disease; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWarnings:\u003c\/b\u003e do not inject intravascularly or intramuscularly. Intravascular injection may cause embolisation, vascular occlusion, ischaemia, skin necrosis, visual disturbances, blindness or stroke. Aspiration before injecting and a low, constant injection pressure are recommended. Do not mix the gel with other products.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the manufacturer's official documentation (instructions for use Restylane® Volyme™, Q-Med AB \/ Galderma). This information sheet does not replace the instructions for use supplied with the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Galderma","offers":[{"title":"Default Title","offer_id":51791954051412,"sku":"RES009","price":88.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/Restylane_Volyme_50b678c8-ea05-4d3c-b864-1fca85354d69.jpg?v=1775491906"},{"product_id":"croma-polyphil","title":"Croma PolyPhil 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eCroma PolyPhil™ is the reference biostimulator of the Croma-Pharma polynucleotide range: 40 mg of PN-HPT® polynucleotides in a 2 ml syringe, \u003cb\u003ewithout hyaluronic acid\u003c\/b\u003e. It is the highest PN concentration in the range and the variant indicated for general skin revitalisation of the face, neck, décolletage, hands and scars.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT®\u003c\/b\u003e 40 mg \/ 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eHyaluronic acid\u003c\/b\u003e not contained\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedles\u003c\/b\u003e 2 × 30G ½\"\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT® polynucleotides:\u003c\/b\u003e 40 mg per 2 ml syringe (20 mg\/ml), obtained from freshwater trout from controlled European aquaculture, with full traceability of the production chain.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWithout hyaluronic acid:\u003c\/b\u003e unlike PolyPhil Next, the classic formulation does not incorporate HA. All the active content is polynucleotide, which directs it towards pure biostimulation rather than immediate hydration.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePN-HPT® (Polynucleotide High Purification Technology):\u003c\/b\u003e Croma's proprietary purification process that guarantees a high degree of purity of the polynucleotide chain.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism of action:\u003c\/b\u003e the polynucleotides stimulate fibroblast proliferation and the neosynthesis of collagen and elastin, retain water and act as free-radical scavengers, creating an optimal environment for fibroblast activity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the PolyPhil range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil\u003c\/th\u003e\u003ctd\u003ePN-HPT® 40 mg \/ 2 ml, without HA — face, neck, décolletage, hands, scars\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Next\u003c\/th\u003e\u003ctd\u003ePN-HPT® 20 mg + HA 20 mg \/ 2 ml — mature and dehydrated skin, midface, scars and acne scars\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Eye\u003c\/th\u003e\u003ctd\u003ePN-HPT® 15 mg \/ 2 ml — eye contour, eyelids, superficial lines\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePolyPhil Hair\u003c\/th\u003e\u003ctd\u003ePN-HPT® 15 mg \/ 2 ml — scalp and eyebrows\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eNote: the PhilArt line was renamed PolyPhil™ in 2024\/2025. It is the same product and the same formulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eWhole face\u003c\/li\u003e\n\u003cli\u003eNeck and décolletage\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003cli\u003eScars\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEqually indicated as a skin conditioning technique (SET, \u003ci\u003eSkin Enhancement Technique\u003c\/i\u003e) prior to laser, peeling, microneedling or PRP.\u003c\/p\u003e\n\u003cp\u003eNot a volumising product: it improves the quality of the skin without modifying the contour or providing projection.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal — superficial, mid or deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits (multi-puncture) with a spacing of approximately 1 cm, linear retrograde or fanning, with a needle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRecommended needle:\u003c\/b\u003e 30G ½\" (13 mm), 2 units included.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDose:\u003c\/b\u003e 2 ml per session.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e a series of sessions spaced 14 to 21 days apart, followed by maintenance sessions. The binding protocol is that of the instructions for use.\u003c\/li\u003e\n\u003cli\u003eCompatible with combined protocols within the PolyPhil range and with other medical aesthetic treatments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCroma-Pharma GmbH, Austria\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003ePN-HPT® polynucleotides 20 mg\/ml (40 mg per syringe)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin of the polynucleotides\u003c\/th\u003e\u003ctd\u003eFreshwater trout, controlled European aquaculture\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedles\u003c\/th\u003e\u003ctd\u003e2 × 30G ½\" (13 mm)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eApplication plane\u003c\/th\u003e\u003ctd\u003eIntradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eMedical device with CE marking 0373\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, in a dry place protected from sunlight. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2 ml, 2 needles 30G ½\", information for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases or a history thereof; active skin infection or inflammation in the treatment area, including active herpes simplex; coagulation disorders; epilepsy; circulatory disorders; ongoing antibiotic or oncological treatment; under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Croma-Pharma. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Croma Pharma","offers":[{"title":"Default Title","offer_id":51884560613716,"sku":"POL001","price":88.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/polyphil_442a2f65-7084-445f-a8df-11d901431f42.jpg?v=1747485629"},{"product_id":"neauvia-hydro-deluxe-2x2-5ml","title":"Neauvia Hydro Deluxe 2x2.5ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eNeauvia Organic Hydro Deluxe is the skinbooster of the MATEX LAB range: linear, non-cross-linked hyaluronic acid at 18 mg\/ml combined with calcium hydroxyapatite, glycine and L-proline. It is administered by microinjections into the epidermis and dermis of the face and neck with a 30G needle, and is presented in two 2.5 ml syringes. It is the only non-cross-linked reference in the Neauvia range and has its own protocol, distinct from that of the Intense and Stimulate fillers.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eLinear HA\u003c\/b\u003e 18 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWith CaHA\u003c\/b\u003e Yes\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 2 syringes × 2.5 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle\u003c\/b\u003e 30G included\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e Epidermis and dermis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked (linear) hyaluronic acid:\u003c\/b\u003e 18 mg\/ml.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCalcium hydroxyapatite (CaHA):\u003c\/b\u003e present in the formulation; the manufacturer does not publish the concentration.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eGlycine and L-proline\u003c\/b\u003e in phosphate buffer solution.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNo anaesthetic:\u003c\/b\u003e the formulation does not contain lidocaine.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRheological profile:\u003c\/b\u003e low extrusion force, consistent with superficial injection through a 30G needle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eNon-cross-linked product.\u003c\/b\u003e Hydro Deluxe is the only reference in the Neauvia range without cross-linking: the hyaluronic acid is linear, so the PEGDE technology that characterises the Intense and Stimulate lines does not apply. Its function is not volumetric but the treatment of skin quality in the epidermis and dermis, and its persistence is correspondingly short: the manufacturer states up to 4 weeks, with a mean time of 2 weeks. This figure is the persistence of the implant, not the duration of the perceived clinical effect, and explains why the product is used in a scheme of repeated sessions rather than as a single application.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGlycine and L-proline.\u003c\/b\u003e Both proteinogenic amino acids are added to the buffer solution to adjust the viscoelastic properties and the swelling resistance of the hydrogel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Neauvia Organic range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eProduct\u003c\/th\u003e\u003ctd\u003e\u003cb\u003eHA\u003c\/b\u003e · cross-linking · extrusion force · plane · area\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eHydro Deluxe \/ Hydro Deluxe Man\u003c\/th\u003e\u003ctd\u003e18 mg\/ml · non-cross-linked (linear) + CaHA · low · epidermis and dermis · face and neck\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rheology\u003c\/th\u003e\u003ctd\u003e22 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Lips\u003c\/th\u003e\u003ctd\u003e24 mg\/ml · PEG · medium · vermilion and\/or perioral area · lips\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Flux\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense LV\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG · medium\/high · intradermal and\/or subcutaneous · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eStimulate \/ Stimulate Man\u003c\/th\u003e\u003ctd\u003e26 mg\/ml · PEG \u003cb\u003e+ calcium hydroxyapatite\u003c\/b\u003e · medium\/high · subdermis and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense \/ Intense Man\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · subcutaneous and\/or supraperiosteal · face\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIntense Rose\u003c\/th\u003e\u003ctd\u003e28 mg\/ml · PEG · high · intradermal · labia majora (gynaecological indication)\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe entire range shares the same formulation backbone: hyaluronic acid of biotechnological origin cross-linked with PEGDE (polyethylene glycol diglycidyl ether), buffered in phosphate solution and enriched with glycine and L-proline. The difference between references lies in the HA concentration, the resulting rheology and the intended injection plane, not in the cross-linking chemistry. Hydro Deluxe is the only non-cross-linked reference; Stimulate is the only one that incorporates calcium hydroxyapatite in the gel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBiodegradable linear hyaluronic acid hydrogel intended for the treatment of skin quality by injection into the epidermis and dermis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace\u003c\/li\u003e\n\u003cli\u003eNeck\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe manufacturer limits the injection area to the face and neck; it publishes no indication for the décolletage or the dorsum of the hands.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e epidermis and dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAreas:\u003c\/b\u003e face and neck.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e 30G, included in the pack.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e superficial microinjections (multiple puncture or nappage) distributed evenly over the treated area.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePersistence of the product:\u003c\/b\u003e up to 4 weeks, with a mean time of 2 weeks according to manufacturer data. Given this persistence, treatment is planned as repeated sessions; the manufacturer does not publish a fixed number of sessions or a standardised interval, so the regimen must be set according to clinical judgement.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCombination therapy:\u003c\/b\u003e the manufacturer integrates the reference into two of its own synergistic protocols, one for the mid third of the face and one for restoration of the epidermis, in combination with cross-linked fillers from the range.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMATEX LAB S.p.A. — via Carlo Urbani 2 ang. via Enrico Fermi, Brindisi (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid 18 mg\/ml + calcium hydroxyapatite\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCross-linking\u003c\/th\u003e\u003ctd\u003eNon-cross-linked (linear hyaluronic acid)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOther components\u003c\/th\u003e\u003ctd\u003eGlycine, L-proline; phosphate buffer solution\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAnaesthetic\u003c\/th\u003e\u003ctd\u003eNot contained\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e2 pre-filled syringes of 2.5 ml (5.0 ml in total)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNeedle\u003c\/th\u003e\u003ctd\u003e30G included\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eExtrusion force\u003c\/th\u003e\u003ctd\u003eLow\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eEpidermis and dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAreas\u003c\/th\u003e\u003ctd\u003eFace and neck\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePersistence\u003c\/th\u003e\u003ctd\u003eUp to 4 weeks; 2 weeks on average\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eClass III medical device with CE marking (EU Regulation 2017\/745, MDR)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only, trained in hyaluronic acid filler injection techniques\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 2 pre-filled syringes of 2.5 ml, 30G needle, package leaflet and traceability labels.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSterile pre-filled syringes, ready for use.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003eStore under the conditions indicated on the pack, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eThe traceability labels supplied must be attached to the patient record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eThe manufacturer restricts use to physicians acting in accordance with local legislation and trained in hyaluronic acid filler injection techniques.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMust not be applied in the case of:\u003c\/b\u003e known hypersensitivity to any of the components of the product; active skin infection, inflammation or lesion in the treatment area; pregnancy and breastfeeding; patients under the age of majority.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIndividual assessment:\u003c\/b\u003e autoimmune disease or immunosuppressive therapy; tendency to hypertrophic or keloid scarring; anticoagulant or antiplatelet therapy; presence of permanent implants in the area.\u003c\/p\u003e\n\u003cp\u003eDo not inject intravascularly. Sterile single-use product: do not reuse or re-sterilise; discard syringes and needles after the procedure.\u003c\/p\u003e\n\u003cp\u003eThe full contraindications, warnings and possible adverse effects are listed in the package leaflet accompanying the pack and must be consulted before each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of MATEX LAB S.p.A. (Neauvia product data sheets and the manufacturer's technical pages) and on peer-reviewed literature on PEG cross-linked hyaluronic acid hydrogels. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"MatexLab","offers":[{"title":"Default Title","offer_id":51909405802836,"sku":"NEA001","price":78.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/neauvia_hydro_deluxe_4648e023-3153-4f49-8cd9-540e0648ed1d.jpg?v=1753530389"},{"product_id":"aquashine-soft-filler-br-1x2ml","title":"Aquashine Soft Filler BR 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eAquashine Soft Filler BR, from the Revofil line of Caregen Co., Ltd. (South Korea), is the variant of the Aquashine range directed at pigmentation control. On the same base of non-cross-linked hyaluronic acid at 15 mg\/ml it incorporates a complex of four biomimetic peptides aimed at reducing melanin synthesis in the dermis, in addition to improving elasticity and texture. It is applied in the mid to deep dermis in a regimen of three sessions separated by four weeks.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 15 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eComplex\u003c\/b\u003e 4 biomimetic peptides\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOrientation\u003c\/b\u003e pigmentation\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3 sessions \/ 4 weeks\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 15 mg\/ml. It provides hydration and acts as a vehicle for the active complex.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePeptide complex:\u003c\/b\u003e oligopeptide-34, oligopeptide-51, decapeptide-23 and oligopeptide-72.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism declared by the manufacturer:\u003c\/b\u003e the peptide complex significantly reduces melanin synthesis in the dermis, which translates into an attenuation of hyperpigmentation, solar lentigines and ephelides. The peptides also act on elastin synthesis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApproach:\u003c\/b\u003e it combines the hydration typical of a soft hyaluronic acid filler with the delivery of actives characteristic of mesotherapy, in a single pre-filled syringe.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between Aquashine Soft Filler and Aquashine Soft Filler BR\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBoth references share the same base of non-cross-linked hyaluronic acid at 15 mg\/ml, the same 2.0 ml pre-filled syringe format and the same application protocol. What distinguishes them is the peptide complex incorporated.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eAquashine Soft Filler\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml + oligopeptide-24, multivitamin complex, minerals, coenzymes and amino acids. General revitalising orientation: fine wrinkles, elasticity, skin quality.\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAquashine Soft Filler BR\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml + oligopeptide-34, oligopeptide-51, decapeptide-23 and oligopeptide-72. Additional orientation towards the control of melanin synthesis in the dermis: hyperpigmentation, lentigines and ephelides.\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThis data sheet corresponds to \u003cb\u003eAquashine Soft Filler BR\u003c\/b\u003e, the reference in the range oriented towards pigmentation control.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable product indicated for dermal revitalisation with an orientation towards pigmentation control in adult patients.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDiffuse hyperpigmentation\u003c\/li\u003e\n\u003cli\u003eSolar lentigines and ephelides\u003c\/li\u003e\n\u003cli\u003eUneven skin tone\u003c\/li\u003e\n\u003cli\u003eLoss of elasticity and firmness\u003c\/li\u003e\n\u003cli\u003eFine wrinkles and uneven texture\u003c\/li\u003e\n\u003cli\u003eEnlarged pores\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTreatment areas:\u003c\/b\u003e face, neck, décolletage and dorsum of the hands.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAngle:\u003c\/b\u003e approximately 30°, with the needle parallel to the direction of the wrinkle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechniques:\u003c\/b\u003e retrograde linear threading, serial puncture, cross-hatching or serial threading, according to the area and the objective.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e fine-gauge sterile needle. The manufacturer does not publish a single gauge; use the one supplied with the product or the one indicated in the instructions for use.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e \u003cb\u003e3 sessions with an interval of 4 weeks\u003c\/b\u003e between them.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration of the result:\u003c\/b\u003e up to 6 months according to the manufacturer, with the possibility of maintenance sessions.\u003c\/li\u003e\n\u003cli\u003eSingle-use product: discard the remainder in the syringe after the session.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCaregen Co., Ltd. — South Korea (Revofil line)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid 15 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive complex\u003c\/th\u003e\u003ctd\u003eOligopeptide-34, oligopeptide-51, decapeptide-23, oligopeptide-72\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003e3 sessions, interval of 4 weeks\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e keep in the original packaging, protected from direct sunlight, under the temperature conditions indicated on it. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2.0 ml, package leaflet and 2 traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e pregnancy and breastfeeding; under 18 years of age; known hypersensitivity to hyaluronic acid or to any of the components of the formulation; active skin infection or inflammation in the treatment area; tendency to hypertrophic or keloid scarring; active autoimmune disease.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e do not apply in areas with previous permanent implants. Do not combine in the same session with ablative laser, deep peeling or dermabrasion. Assess individually in patients on anticoagulant or antiplatelet therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNever inject intravascularly.\u003c\/b\u003e Always consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eProduct intended exclusively for qualified healthcare professionals. Technical information based on the documentation of the manufacturer Caregen Co., Ltd. and of its official distribution. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Caregen","offers":[{"title":"Default Title","offer_id":51909450891604,"sku":"AQS003","price":46.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/aquashine_soft_filler.jpg?v=1747759839"},{"product_id":"aquashine-soft-filler","title":"Aquashine Soft Filler 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eAquashine Soft Filler, from the Revofil line of Caregen Co., Ltd. (South Korea), is an injectable dermal revitaliser that combines non-cross-linked hyaluronic acid at 15 mg\/ml with a complex of biomimetic peptides, multivitamins, minerals and amino acids. It is not a volumetric filler: it is applied in the mid to deep dermis as biostimulation of skin quality, in a regimen of three sessions separated by four weeks.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e 15 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eComplex\u003c\/b\u003e peptides + vitamins + amino acids\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 syringe × 2.0 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e mid to deep dermis\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3 sessions \/ 4 weeks\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked hyaluronic acid:\u003c\/b\u003e 15 mg\/ml. It provides hydration and acts as a vehicle for the active complex.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePeptide complex\u003c\/b\u003e with oligopeptide-24, directed at dermal revitalisation.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMultivitamins:\u003c\/b\u003e retinol, ascorbic acid, folic acid and thiamine nitrate.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMinerals and coenzymes:\u003c\/b\u003e sodium phosphate, magnesium sulfate, calcium chloride and potassium chloride.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAmino acids:\u003c\/b\u003e alanine, aspartic acid, glutamic acid and aminobutyric acid.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eApproach:\u003c\/b\u003e it combines the hydration typical of a soft hyaluronic acid filler with the delivery of actives characteristic of mesotherapy, in a single pre-filled syringe.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eDifferences between Aquashine Soft Filler and Aquashine Soft Filler BR\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eBoth references share the same base of non-cross-linked hyaluronic acid at 15 mg\/ml, the same 2.0 ml pre-filled syringe format and the same application protocol. What distinguishes them is the peptide complex incorporated.\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eAquashine Soft Filler\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml + oligopeptide-24, multivitamin complex, minerals, coenzymes and amino acids. General revitalising orientation: fine wrinkles, elasticity, skin quality.\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eAquashine Soft Filler BR\u003c\/th\u003e\u003ctd\u003eHA 15 mg\/ml + oligopeptide-34, oligopeptide-51, decapeptide-23 and oligopeptide-72. Additional orientation towards the control of melanin synthesis in the dermis: hyperpigmentation, lentigines and ephelides.\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThis data sheet corresponds to \u003cb\u003eAquashine Soft Filler\u003c\/b\u003e, the reference in the range with a general revitalising orientation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable product indicated for dermal revitalisation and the improvement of skin quality in adult patients.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFine wrinkles and superficial lines\u003c\/li\u003e\n\u003cli\u003eLoss of elasticity and firmness\u003c\/li\u003e\n\u003cli\u003eSkin dehydration\u003c\/li\u003e\n\u003cli\u003eUneven texture and enlarged pores\u003c\/li\u003e\n\u003cli\u003eDull skin and lack of radiance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eTreatment areas:\u003c\/b\u003e face, neck, décolletage and dorsum of the hands.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e mid to deep dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAngle:\u003c\/b\u003e approximately 30°, with the needle parallel to the direction of the wrinkle.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechniques:\u003c\/b\u003e retrograde linear threading, serial puncture, cross-hatching or serial threading, according to the area and the objective.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e fine-gauge sterile needle. The manufacturer does not publish a single gauge; use the one supplied with the product or the one indicated in the instructions for use.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e \u003cb\u003e3 sessions with an interval of 4 weeks\u003c\/b\u003e between them.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDuration of the result:\u003c\/b\u003e up to 6 months according to the manufacturer, with the possibility of maintenance sessions.\u003c\/li\u003e\n\u003cli\u003eSingle-use product: discard the remainder in the syringe after the session.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eCaregen Co., Ltd. — South Korea (Revofil line)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substance\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid 15 mg\/ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive complex\u003c\/th\u003e\u003ctd\u003eOligopeptide-24, multivitamins, minerals, coenzymes and amino acids\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 pre-filled syringe of 2.0 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eInjection plane\u003c\/th\u003e\u003ctd\u003eMid to deep dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eProtocol\u003c\/th\u003e\u003ctd\u003e3 sessions, interval of 4 weeks\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e keep in the original packaging, protected from direct sunlight, under the temperature conditions indicated on it. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 1 pre-filled syringe of 2.0 ml, package leaflet and 2 traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eContraindications:\u003c\/b\u003e pregnancy and breastfeeding; under 18 years of age; known hypersensitivity to hyaluronic acid or to any of the components of the formulation; active skin infection or inflammation in the treatment area; tendency to hypertrophic or keloid scarring; active autoimmune disease.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003c\/b\u003e do not apply in areas with previous permanent implants. Do not combine in the same session with ablative laser, deep peeling or dermabrasion. Assess individually in patients on anticoagulant or antiplatelet therapy.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNever inject intravascularly.\u003c\/b\u003e Always consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eProduct intended exclusively for qualified healthcare professionals. Technical information based on the documentation of the manufacturer Caregen Co., Ltd. and of its official distribution. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Caregen","offers":[{"title":"Default Title","offer_id":51909463572820,"sku":"AQS002","price":46.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/aquashine_soft_filler_6f23563b-324e-47f8-85ec-c5fe48c00f93.jpg?v=1747760231"},{"product_id":"newest-one-5x4ml","title":"Newest One 5x4ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eNewest® One is the large-volume presentation of the Newest line from Mastelli S.r.l.: 5 vials of 4 ml with PN-HPT® polynucleotides, non-cross-linked hyaluronic acid and mannitol. It reproduces the principle of Newest — biostimulation and hydration in a single solution — in a diluted formulation designed to treat extensive areas of the face and body.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eActives\u003c\/b\u003e PN-HPT® + non-cross-linked HA\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eWith mannitol\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 5 vials × 4 ml (20 ml)\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e intradermal\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol\u003c\/b\u003e 3–4 sessions \/ 14–21 days\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eDeclared composition:\u003c\/b\u003e water, PN-HPT® polynucleotides, sodium hyaluronate, mannitol, sodium chloride, sodium phosphate and disodium phosphate.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eDiluted formulation:\u003c\/b\u003e this is the low-concentration version of the Newest line, adjusted for the treatment of large surfaces. Mastelli does not publish a single, verifiable mg\/ml figure for this reference; the exact concentrations should be consulted on the pack data sheet. To know precisely the PN-HPT® and hyaluronic acid delivered per session, the documented reference in the line is Newest in a 2 ml syringe (PN-HPT® 10 mg\/ml + HA 10 mg\/ml).\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eOrigin of the polynucleotides:\u003c\/b\u003e trout gonads from aquaculture intended for human consumption, subjected to Mastelli's proprietary high-purification process, which removes proteins and contaminants of potential allergenic character.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMechanism of action:\u003c\/b\u003e the polynucleotides stimulate the fibroblast to synthesise glycosaminoglycans, collagen and elastin and bind water in the extracellular matrix; the non-cross-linked hyaluronic acid provides hydration without generating volume. Mannitol is included as an antioxidant excipient.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Mastelli range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003ePlinest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 20 mg\/ml (40 mg \/ 2 ml) — 1 syringe of 2 ml. High concentration: face, neck, décolletage and dorsum of the hands\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Fast\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml (15 mg \/ 2 ml) — 1 syringe of 2 ml. Low concentration for thin or sensitive skin and for skin preparation\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Eye\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Periocular indication\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest Hair\u003c\/th\u003e\u003ctd\u003ePN-HPT® 7.5 mg\/ml — 1 syringe of 2 ml. Indication for the scalp, eyebrows and beard\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePlinest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® 2 mg\/ml (8 mg per 4 ml vial) — 5 vials of 4 ml. Diluted formulation for large surfaces and the body\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest\u003c\/th\u003e\u003ctd\u003ePN-HPT® 10 mg\/ml + non-cross-linked HA 10 mg\/ml + mannitol — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eNewest One\u003c\/th\u003e\u003ctd\u003ePN-HPT® + non-cross-linked HA + mannitol in diluted formulation — 5 vials of 4 ml, body and large surfaces\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eIalest\u003c\/th\u003e\u003ctd\u003eNon-cross-linked HA 20 mg\/ml (2 %), without polynucleotides — 1 syringe of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eNewest One and Plinest One share the same format (5 vials of 4 ml) and large-surface indication; the difference is that Newest One incorporates non-cross-linked hyaluronic acid and mannitol, and Plinest One does not. Plenhyage XL Strong, which is marketed alongside this range, \u003cb\u003edoes not belong to the Mastelli family\u003c\/b\u003e: it is a brand of Bioformula S.r.l.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eDry, dehydrated or dull skin over extensive surfaces\u003c\/li\u003e\n\u003cli\u003eLoss of firmness and elasticity\u003c\/li\u003e\n\u003cli\u003eStretch marks and scars\u003c\/li\u003e\n\u003cli\u003eRevitalisation after procedures and in skin with irregular texture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eAreas:\u003c\/b\u003e face, neck, décolletage, dorsum of the hands, arms, abdomen, buttocks and inner thighs.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e intradermal.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microdeposits or micropapules, linear retrograde or fanning, according to the area.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eNeedle:\u003c\/b\u003e the consensus literature on PN-HPT® recommends 30 to 32G needles of 13 mm.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eVial presentation:\u003c\/b\u003e the product is drawn into a syringe before application; the pack does not include pre-filled syringes.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eProtocol:\u003c\/b\u003e 1 session every 14 or 21 days up to a total of 3 sessions; 4 sessions in advanced signs of ageing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eMastelli S.r.l., Sanremo (Italy)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substances\u003c\/th\u003e\u003ctd\u003ePN-HPT® polynucleotides + non-cross-linked hyaluronic acid (sodium hyaluronate)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOther components\u003c\/th\u003e\u003ctd\u003eMannitol, sodium chloride, sodium phosphate, disodium phosphate, water\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eOrigin of the polynucleotides\u003c\/th\u003e\u003ctd\u003eTrout gonads from aquaculture, highly purified\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e5 vials of 4.0 ml (20 ml in total)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eCE-marked medical device\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStorage:\u003c\/b\u003e between 2 °C and 25 °C, protected from direct sunlight and heat sources. Do not freeze.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the pack.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product: one vial per session. Do not reuse, re-sterilise or keep the remaining contents of an opened vial.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eThe pack contains:\u003c\/b\u003e 5 vials of 4 ml, instructions for use and traceability labels.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eKnown hypersensitivity to any of the components; pregnancy and breastfeeding; active autoimmune diseases; active skin infection or inflammation in the treatment area; coagulation disorders or anticoagulant therapy; ongoing oncological treatment; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eAs this is a product of fish origin, assess any history of fish allergy before application.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application. The binding contraindications are those set out in the official documentation accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the documentation of Mastelli S.r.l. and on the published clinical literature on PN-HPT®. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Mastelli","offers":[{"title":"Default Title","offer_id":51910452838740,"sku":"NEW001","price":92.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/newest_one_bac851a1-33c7-49bf-a28a-6cb88f0c8c65.jpg?v=1747773222"},{"product_id":"cytocare-532-10x5ml","title":"Cytocare 532 10x5ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eCytocare® 532 is the mesotherapy cocktail from Laboratoire Revitacare (France) that combines non-cross-linked hyaluronic acid with the CT50 rejuvenating complex, a set of 50 nutrients formulated by the laboratory: amino acids, B-group vitamins, minerals and sources of cellular energy. It is the highest concentration in the 502-516-532 numbered series, indicated for mature skin. Box of 10 vials of 5 ml.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eNon-cross-linked HA\u003c\/b\u003e + CT50 complex\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eCT50\u003c\/b\u003e 50 nutrients\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 10 vials × 5 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003ePlane\u003c\/b\u003e superficial and mid dermis\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eMedical device\u003c\/b\u003e class III\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eNon-cross-linked hyaluronic acid\u003c\/b\u003e combined with the \u003cb\u003eCT50 Rejuvenating Complex\u003c\/b\u003e, described by the manufacturer as a specific complex of 50 nutrients:\u003c\/p\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eAmino acids\u003c\/th\u003e\u003ctd\u003eBuilding blocks of proteins: L-alanine, glutamine, valine, L-cysteine, glutamic acid, L-arginine, among others\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eB-group vitamins\u003c\/th\u003e\u003ctd\u003eB1 (thiamine), B2 (riboflavin), B3 (niacinamide), B5 (calcium pantothenate), B6 (pyridoxine), B7 (biotin), B9 (folic acid), B12 (cyanocobalamin)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eMinerals and trace elements\u003c\/th\u003e\u003ctd\u003eMagnesium, zinc and manganese\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eEnergy sources\u003c\/th\u003e\u003ctd\u003eD-glucose and sodium pyruvate\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe numerical designation of the range identifies the hyaluronic acid load: 502, 516 and 532 share the same CT50 complex and differ in the hyaluronic acid concentration, increasing in that order. Revitacare does not publish the mg\/ml value in its public documentation, so no figure is given here.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003ePosition within the Cytocare® range\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eCytocare® 502\u003c\/th\u003e\u003ctd\u003eLower HA load + CT50 complex — 10 vials × 5 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCytocare® 516\u003c\/th\u003e\u003ctd\u003eIntermediate HA load + CT50 complex — 10 vials × 5 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCytocare® 532\u003c\/th\u003e\u003ctd\u003eHighest HA load in the series + CT50 complex — mature skin — 10 vials × 5 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eCytocare® S Line\u003c\/th\u003e\u003ctd\u003eHA + rejuvenating complex in a 3 ml syringe — 1 syringe per pack\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe three numbered references share the same active formulation and presentation; the choice between them is made according to the degree of photoageing and the need for dermal hydration.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eIndication declared by the manufacturer:\u003c\/b\u003e treatment of periorbital and perioral lines (vertical lip lines) by microinjections into the superficial and mid dermis; improvement of skin quality.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace — periorbital and perioral region\u003c\/li\u003e\n\u003cli\u003eNeck and décolletage\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eInjection plane:\u003c\/b\u003e superficial and mid dermis.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eTechnique:\u003c\/b\u003e microinjections (mesotherapy), on healthy, disinfected skin, under aseptic conditions.\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eAdministration:\u003c\/b\u003e by a physician only.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eRevitacare does not publish in its public documentation the needle gauge, the dose per point or the number of sessions and their interval. The applicable protocol is the one set out in the instructions for use accompanying the pack and in the manufacturer's training.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eManufacturer\u003c\/th\u003e\u003ctd\u003eLaboratoire Revitacare, France\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive substances\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid + CT50 Rejuvenating Complex (50 nutrients)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003eBox of 10 vials of 5 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — superficial and mid dermis\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eSterile class III medical device, single use\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003eBox of 10 sterile vials of 5 ml.\u003c\/li\u003e\n\u003cli\u003eSterile single-use product. Do not reuse or resterilise.\u003c\/li\u003e\n\u003cli\u003eStore as indicated on the packaging, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date shown on the packaging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eContraindications declared by the manufacturer: under 18 years of age; pregnancy and breastfeeding; autoimmune diseases; known allergy to any of the components.\u003c\/p\u003e\n\u003cp\u003eThe usual precautions for intradermal injectables should be added: active skin infection, inflammation or lesion in the treatment area and coagulation disorders.\u003c\/p\u003e\n\u003cp\u003eAlways consult the instructions for use included in the pack before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eMedical device intended exclusively for qualified healthcare professionals. Technical information based on the official documentation of Laboratoire Revitacare. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Revitacare","offers":[{"title":"Default Title","offer_id":51915892457812,"sku":"CYT001","price":210.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/cytocare_532.jpg?v=1747840054"},{"product_id":"geo-bio-revitalizing-60","title":"GEO Bio-Revitalizing 60 1x2ml","description":"\u003cstyle\u003e\n.pe-desc{\n  --pe-ink:#1C235C;\n  --pe-text:#5A6379;\n  --pe-muted:#8A92A6;\n  --pe-line:#E4E7EE;\n  --pe-soft:#F7F8FA;\n  --pe-green:#17564F;\n  --pe-bronze:#9C6B3F;\n  --pe-head:\"Josefin Sans\",\"Nunito\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",sans-serif;\n  color:var(--pe-text);\n  font-size:15px;\n  line-height:1.7;\n}\n.pe-desc *{box-sizing:border-box}\n\n.pe-lead{\n  font-size:16.5px;line-height:1.65;color:#3E465F;\n  margin:0 0 26px;padding:0 0 0 16px;\n  border-left:3px solid var(--pe-ink);\n}\n\n\/* ---- Datenkacheln ---- *\/\n.pe-chips{\n  display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));\n  gap:10px;margin:0 0 30px;padding:0;list-style:none;\n}\n.pe-chips li{\n  margin:0;padding:12px 14px;\n  background:var(--pe-soft);border:1px solid var(--pe-line);border-radius:8px;\n  font-size:15px;font-weight:600;color:var(--pe-ink);line-height:1.35;\n}\n.pe-chips li b{\n  display:block;\n  font-family:var(--pe-head);\n  font-size:10.5px;font-weight:600;letter-spacing:.09em;text-transform:uppercase;\n  color:var(--pe-muted);margin:0 0 5px;\n}\n\n\/* ---- Akkordeon ---- *\/\n.pe-acc{display:flex;flex-direction:column;gap:10px;margin:0}\n.pe-acc details{\n  border:1px solid var(--pe-line);border-radius:10px;\n  background:#fff;overflow:hidden;\n}\n.pe-acc details[open]{border-color:#D3D8E5}\n.pe-acc summary{\n  cursor:pointer;list-style:none;\n  padding:15px 18px;\n  font-family:var(--pe-head);\n  font-size:15.5px;font-weight:600;letter-spacing:.005em;color:var(--pe-ink);\n  display:flex;justify-content:space-between;align-items:center;gap:14px;\n  transition:background .15s ease;\n}\n.pe-acc summary:hover{background:var(--pe-soft)}\n.pe-acc summary::-webkit-details-marker{display:none}\n.pe-acc summary::after{\n  content:\"\";flex:0 0 20px;height:20px;border-radius:50%;\n  border:1.5px solid var(--pe-line);\n  background:\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat,\n    linear-gradient(var(--pe-ink),var(--pe-ink)) center\/1.5px 9px no-repeat;\n  transition:transform .2s ease,border-color .15s ease;\n}\n.pe-acc details[open] summary{background:var(--pe-soft);border-bottom:1px solid var(--pe-line)}\n.pe-acc details[open] summary::after{\n  background:linear-gradient(var(--pe-ink),var(--pe-ink)) center\/9px 1.5px no-repeat;\n  transform:rotate(180deg);border-color:#D3D8E5;\n}\n.pe-acc .pe-body{padding:18px}\n.pe-acc .pe-body\u003ep{margin:0 0 13px}\n.pe-acc .pe-body\u003ep:last-child{margin-bottom:0}\n.pe-acc .pe-body b,.pe-acc .pe-body strong{color:var(--pe-ink);font-weight:600}\n\n.pe-acc ul{margin:0 0 13px;padding:0;list-style:none}\n.pe-acc ul:last-child{margin-bottom:0}\n.pe-acc li{\n  margin:0 0 9px;padding:0 0 0 20px;position:relative;\n}\n.pe-acc li:last-child{margin-bottom:0}\n.pe-acc li::before{\n  content:\"\";position:absolute;left:2px;top:.62em;\n  width:6px;height:6px;border-radius:50%;\n  background:var(--pe-green);\n}\n\n\/* ---- Tabellen ---- *\/\n.pe-tbl{\n  width:100%;border-collapse:collapse;font-size:14.5px;margin:0 0 13px;\n  border:1px solid var(--pe-line);border-radius:8px;overflow:hidden;\n}\n.pe-tbl:last-child{margin-bottom:0}\n.pe-tbl th,.pe-tbl td{text-align:left;padding:11px 14px;vertical-align:top;line-height:1.55}\n.pe-tbl th{\n  font-family:var(--pe-head);\n  font-weight:600;color:var(--pe-ink);width:42%;\n  background:var(--pe-soft);border-right:1px solid var(--pe-line);\n}\n.pe-tbl tr+tr th,.pe-tbl tr+tr td{border-top:1px solid var(--pe-line)}\n\n\/* ---- Schlusshinweis ---- *\/\n.pe-note{\n  margin:24px 0 0;padding:14px 16px;\n  background:var(--pe-soft);border-radius:8px;\n  border-left:3px solid var(--pe-bronze);\n  font-size:13px;line-height:1.6;color:var(--pe-muted);\n}\n\n@media (max-width:600px){\n  .pe-chips{grid-template-columns:repeat(auto-fit,minmax(128px,1fr));gap:8px}\n  .pe-chips li{padding:10px 12px;font-size:14.5px}\n  .pe-acc summary{padding:14px 15px;font-size:15px}\n  .pe-acc .pe-body{padding:15px}\n  .pe-tbl th,.pe-tbl td{padding:10px 11px;font-size:14px}\n  .pe-tbl th{width:46%}\n}\n\u003c\/style\u003e\n\u003cdiv class=\"pe-desc\"\u003e\n\u003cp class=\"pe-lead\"\u003eGEO Bio-Revitalizing 60 is an injectable biostimulator from the GEO line, distributed by Medisepte, formulated with non-cross-linked hyaluronic acid combined with a multi-active complex. It is supplied in a single-dose 2 ml vial. This data sheet is deliberately limited to information we have been able to verify: the manufacturer does not publish accessible technical documentation for this reference, and therefore no concentrations or numerical protocols are stated here.\u003c\/p\u003e\n\n\u003cul class=\"pe-chips\"\u003e\n\u003cli\u003e\u003cb\u003eType\u003c\/b\u003e injectable biostimulator\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eBase\u003c\/b\u003e non-cross-linked HA + multi-active complex\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eContents\u003c\/b\u003e 1 vial × 2 ml\u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eRange\u003c\/b\u003e GEO — Medisepte\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cdiv class=\"pe-acc\"\u003e\n\n\u003cdetails open\u003e\n\u003csummary\u003eComposition and technology\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eGEO Bio-Revitalizing 60 consists of non-cross-linked hyaluronic acid in combination with a multi-active skin revitalisation complex, of the type commonly used in mesotherapy and dermal biostimulation.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNote on the figures:\u003c\/b\u003e it has not been possible to verify the hyaluronic acid concentration or the detailed composition of the complex (number and proportion of amino acids, vitamins, minerals, coenzymes and nucleotides) in manufacturer documentation. As a matter of editorial policy, these values are not reproduced here. For binding details, please consult the package insert accompanying the product or request the manufacturer's technical data sheet from us.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eIndications and treatment areas\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003e\u003cb\u003eUsual indications for this product category:\u003c\/b\u003e loss of firmness and skin density, dehydration, dull skin and early signs of ageing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFace\u003c\/li\u003e\n\u003cli\u003eNeck and décolleté\u003c\/li\u003e\n\u003cli\u003eDorsum of the hands\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnique and treatment protocol\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eInjectable product for intradermal administration by microinjection, on healthy, disinfected skin, under aseptic conditions and by a qualified healthcare professional.\u003c\/p\u003e\n\u003cp\u003eWe have no manufacturer documentation specifying the needle gauge, the dose per point, the number of sessions or the interval between them. The binding protocol is the one set out in the instructions for use included in the packaging.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eTechnical data\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003ctable class=\"pe-tbl\"\u003e\n\u003ctr\u003e\u003cth\u003eBrand \/ distributor\u003c\/th\u003e\u003ctd\u003eGEO — Medisepte\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eActive ingredients\u003c\/th\u003e\u003ctd\u003eNon-cross-linked hyaluronic acid + multi-active complex (detailed composition not verified)\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003ePresentation\u003c\/th\u003e\u003ctd\u003e1 vial of 2 ml\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eRoute of administration\u003c\/th\u003e\u003ctd\u003eInjectable — intradermal\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eClassification\u003c\/th\u003e\u003ctd\u003eNot verified in manufacturer documentation; please refer to the packaging labelling\u003c\/td\u003e\u003c\/tr\u003e\n\u003ctr\u003e\u003cth\u003eUse\u003c\/th\u003e\u003ctd\u003eQualified healthcare professionals only\u003c\/td\u003e\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eStorage and pack contents\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cul\u003e\n\u003cli\u003e1 sterile 2 ml vial.\u003c\/li\u003e\n\u003cli\u003eSingle-use product. Do not reuse or re-sterilise.\u003c\/li\u003e\n\u003cli\u003eStore as indicated on the packaging, protected from direct sunlight.\u003c\/li\u003e\n\u003cli\u003eDo not use after the expiry date stated on the packaging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003eContraindications and warnings\u003c\/summary\u003e\n\u003cdiv class=\"pe-body\"\u003e\n\u003cp\u003eGeneral precautions applicable to intradermal injectables: known hypersensitivity to any of the components; active infection, inflammation or skin lesion in the treatment area; coagulation disorders; autoimmune diseases; pregnancy and breastfeeding; patients under 18 years of age.\u003c\/p\u003e\n\u003cp\u003eThe binding contraindications are exclusively those set out in the official documentation accompanying the product. Always consult it before application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003c\/div\u003e\n\n\u003cp class=\"pe-note\"\u003eProduct intended exclusively for qualified healthcare professionals. No public technical documentation from the manufacturer has been located for this reference; this data sheet has been written restrictively and deliberately omits values that cannot be verified. This data sheet does not replace the instructions for use accompanying the product.\u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"Medisepte","offers":[{"title":"Default Title","offer_id":51916261196116,"sku":"GEO001","price":36.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/8943\/2916\/files\/geo_3f06d938-fe67-4ad6-ab87-757917843d51.jpg?v=1747847229"}],"url":"https:\/\/pieleterna.es\/en\/collections\/productos-para-el-rostro-1.oembed?page=3","provider":"Piel Eterna","version":"1.0","type":"link"}